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A model for self-organization of sensorimotor function : The spinal monosynaptic loop

Recent spinal cord literature abounds with descriptions of genetic preprogramming and the molecular control of circuit formation. In this paper, we explore to what extent circuit formation based on learning rather than preprogramming could explain the selective formation of the monosynaptic projections between muscle spindle primary afferents and homonymous motoneurons. We adjusted the initially r

Treatment seeking for alcohol-related issues during the COVID-19 pandemic : An analysis of an addiction-specialized psychiatric treatment facility

The COVID-19 pandemic and its societal impact may cause long-term behavioral changes in alcohol use due to increased psychological distress, unemployment, and time spent home. The purpose of this study was to determine whether or not the COVID-19 pandemic had a significant impact on treatment seeking for alcohol use disorders and related problems in a Swedish psychiatric treatment facility. Using

Kring Fakiren

Den lundensiske 1800-talshumoristen, diktaren och journalisten Axel Wallengren (1865–96) är mest känd under signaturen Falstaff, fakir. Den här boken anlägger skilda perspektiv på personen Wallengren själv, på hans texter och på en rad personer som direkt eller indirekt kan ha inspirerats av honom. Det handlar dels om sådana som ingick i den mycket kreativa miljö som 1890-talets Lund utgjorde, del

Preliminary studies on the role of ten-a during CNS and eye development of Drosophila.

ten-a is one of the two Drosophila genes whose products belong to the Ten M protein family. TheTen-a protein is a type II transmembrane protein. This protein was found to be mainly expressed in the CNSof the embryo and in the compound eye of the pupa. No report about the function of ten-a has beenpublished to date. Here, we showed, in a preliminary report, that ten-a has a function in the developm

Splice variants of the Drosophila PS2 integrins differentially interact with the extracellular ligands Tiggrin, D-laminin alpha 2 and Ten-m.

Two new potential ligands of theDrosophila PS2 integrins have been characterized by functional interaction in cell culture. These potential ligands are a new Drosophila laminin α2 chain encoded by the wing blister locus and Ten-m, an extracellular protein known to be involved in embryonic pattern formation. As with previously identified PS2 ligands, both contain RGD sequences, and RGD-containing f

Diagnosis and treatment of the rare procedural complication of malpositioned pacing leads in the left heart: a single center experience

Objectives. This study assessed the management approach and outcome of the pacemaker or implantable cardioverter-defibrillator (ICD) leads malpositioned in the left heart. Malpositioned leads (MPLs) may have deleterious consequences, and appropriate management remains uncertain. Methods. The study population included all patients referred to a single institution for MPL in the left side of the hea

Anatomy of the coronary sinus with regard to cardiac resynchronization therapy implantation

Knowledge of the coronary sinus (CS) anatomy is crucial for implantation of cardiac resynchronization therapy (CRT). Obstacles to CS entry, such as the Eustachian ridge and Thebesian valve, as well as within the CS, such as Vieussen’s valve and the vein of Marshall, are important to understand and differentiate during implantation or to identify earlier by imaging. Anatomic knowledge is mandatory

The Influence of Age on Cerebral Tissue Oxygenation in Vasovagal Syncope and Orthostatic Hypotension

Age-related physiological impairment increases susceptibility to syncope. We tested the hypotheses that cerebral oxygenation during orthostatic provocation, as well as the level at which syncope occurs, differs according to age. Non-invasive hemodynamic monitoring and cerebral oximetry were applied during a head-up tilt test in 139 patients with vasovagal syncope (mean (SD) 45, (17) years, 60%-fem

Acute Hemodynamic Effects of Simultaneous and Sequential Multi-Point Pacing in Heart Failure Patients With an Expected Higher Rate of Sub-response to Cardiac Resynchronization Therapy : Results of Multicenter SYNSEQ Study

The aim of the SYNSEQ (Left Ventricular Synchronous vs. Sequential MultiSpot Pacing for CRT) study was to evaluate the acute hemodynamic response (AHR) of simultaneous (3P-MPP syn) or sequential (3P-MPP seq) multi-3-point-left-ventricular (LV) pacing vs. single point pacing (SPP) in a group of patients at risk of a suboptimal response to cardiac resynchronization therapy (CRT). Twenty five patient

Selection of Weather Files and Their Importance for Building Performance Simulations in the Light of Climate Change and Urban Heat Islands

Building performance predictions and their reliability rely heavily on weather data inputs. Climate is affected by spatial and temporal differences related to climate change and urban heat island effects, but the weather files used in building performance simulations (BPS) often remain unchanged and may represent weather observations generated from inadequate space and time for their application.

Reliability of data on percent consonants correct and its associated quality indicator in the Swedish cleft lip and palate registry

BACKGROUND: Data in national health care quality registries must be valid and reliable in order to enable open comparisons of results.AIM: To assess the reliability of data on percent consonants correct (PCC) and its associated quality indicator ≥86% correct consonants in the Swedish quality registry for patients born with cleft lip and palate (CLP) registry.METHODS: Six independent speech-languag

Inter-centre comparison of data on surgery and speech outcomes at 5 years of age based on the Swedish quality registry for patients born with cleft palate with or without cleft lip

BACKGROUND: The objective of the Swedish cleft lip and palate registry (CLP registry) is to promote quality control, research and improvement of treatment, by the comparison of long-term results. The aim was to compare data from the CLP registry among the six treatment centres, regarding data on surgery and speech outcomes at 5 years of age.METHODS: The participants were 430 children born in Swede