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Low achromatic contrast sensitivity in birds : a common attribute shared by many phylogenetic orders

Vision is an important sensory modality in birds, which can outperform other vertebrates in some visual abilities. However, sensitivity to achromatic contrasts - the ability to discern luminance difference between two objects or an object and its background - has been shown to be lower in birds compared with other vertebrates. We conducted a comparative study to evaluate the achromatic contrast se

Detecting Weak Underwater Targets Using Block Updating of Sparse and Structured Channel Impulse Responses

In this paper, we considered the real-time modeling of an underwater channel impulse response (CIR), exploiting the inherent structure and sparsity of such channels. Building on the recent development in the modeling of acoustic channels using a Kronecker structure, we approximated the CIR using a structured and sparse model, allowing for a computationally efficient sparse block-updating algorithm

How to Detect Antibodies Against Babesia divergens in Human Blood Samples

Background. Today only indirect fluorescent antibody assays (IFAs) are commercially available to detect antibodies against Babesia divergens in humans. IFA is subjective and requires highly experienced staff. We have therefore developed an enzyme-linked immunosorbent assay (ELISA)-based method for measuring anti-B. divergens immunoglobulin G antibodies in human blood samples. Methods. Crude merozo

The galactic acceleration scale is imprinted on globular cluster systems of early-type galaxies of most masses and on red and blue globular cluster subpopulations

Context. Globular clusters (GCs) carry information about the formation histories and gravitational fields of their host galaxies. It was found before that the radial profiles of the volume number density of GCs in GC systems (GCSs) follow broken power laws, while the breaks occur approximately at the a0 radii. These are the radii at which the gravitational fields of the galaxies equal the galactic

Patient-reported outcomes in axial spondyloarthritis and psoriatic arthritis patients treated with secukinumab for 24 months in daily clinical practice

Objectives: In patients with axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA) initiating secukinumab, we aimed to assess and compare the proportion of patients achieving 6-, 12- and 24-month patient-reported outcomes (PRO) remission and the 24-month retention rates. Patients and methods: Patients with axSpA or PsA from 16 European registries, who initiated secukinumab in routine care w

Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites

Self-replication of amyloid fibrils via secondary nucleation is an intriguing physicochemical phenomenon in which existing fibrils catalyze the formation of their own copies. The molecular events behind this fibril surface-mediated process remain largely inaccessible to current structural and imaging techniques. Using statistical mechanics, computer modeling, and chemical kinetics, we show that th

Digital PCR quantification of ultrahigh ERBB2 copy number identifies poor breast cancer survival after trastuzumab

HER2/ERBB2 evaluation is necessary for treatment decision-making in breast cancer (BC), however current methods have limitations and considerable variability exists. DNA copy number (CN) evaluation by droplet digital PCR (ddPCR) has complementary advantages for HER2/ERBB2 diagnostics. In this study, we developed a single-reaction multiplex ddPCR assay for determination of ERBB2 CN in reference to

From gesture to Sign? : An exploration of the effects of communicative pressure, interaction and time on the process of conventionalization

This study explored how non-signers exploit their gestural repertoire during a process of handshape conventionalisation. We examined how communicative context, interaction and time affect the transition from iconically-motivated representations to linguistically-organised, generalised forms. 100 non-signers undertook a silent gesture-elicitation task, describing pictures in one of four conditions:

Health and safety management of hand-arm vibration : preconditions and outcomes

The overall aim of the research presented in this thesis was to gain increased knowledge and understanding of aspects and actors that contribute to the preconditions and outcomes for proactive health and safety managementregarding vibration exposure. The main objectives were: 1) to investigate carpenters´ perceptions of the proactive health and safety management at their work sites, and 2) to carr

A Population-Based Study on the Incidence, Risk Factors, and Outcome of Salmonella Bloodstream Infections in South Sweden 2012–2022

IntroductionInvasive infections caused by Salmonella are a significant global health concern. This population-based study aimed to comprehensively analyze invasive Salmonella infections in South Sweden, focusing on incidence, clinical presentation, risk factors, and outcomes.MethodsThis population-based observational cohort study, conducted from 2012 to 2022, included all patients with Salmonella

Association between dietary pesticide exposure profiles and body weight change in French adults : Results from the NutriNet-Santé cohort

BACKGROUND: Pesticides cause a wide range of deleterious health effects, including metabolic disorders. Little is known about the effects of dietary pesticide exposure on body weight (BW) change in the general population. We aimed to investigate the role of dietary pesticide exposure in BW change among NutriNet-Santé participants, focusing on potential sexual dimorphism.METHODS: Participants compl

Selective and Concentrative Enteropancreatic Recirculation of Antibiotics by Pigs

Antibiotics that are efficacious for infectious pancreatitis are present in pancreatic exocrine secretion (PES) after intravenous administration and above minimal inhibitory concentrations. We measured concentrations of four antibiotics by tandem liquid chromatography–mass spectroscopy in plasma and PES after enteral administration to juvenile pigs with jugular catheters and re-entrant pancreatic-

Being a non-native English speaker in science and medicine

The use of English language as the official language in science had an undoubtable role in moving science forward but posed an extra challenge for people whose first language is not English. In this Viewpoint, six non-Native English speakers share their experience as academics, clinicians, researchers and editors who carry out the core tasks of their jobs in a second language, and suggest potentia

Vitamin D insufficiency in infants with increased risk of developing type 1 diabetes : A secondary analysis of the POInT Study

Background Vitamin D insufficiency (VDI) may be a factor in the development of type 1 diabetes (T1D). The aim of this study is to investigate the presence and persistence of VDI in a large cohort of infants with increased risk of developing T1D, in light of the differences in local supplementation guidelines. Methods In the POInT Study, a multicentre primary prevention study between February 2018

The association between water intake and future cardiometabolic disease outcomes in the Malmö Diet and Cancer cardiovascular cohort

The aim of this study was to explore the longitudinal association between reported baseline water intake and incidence of coronary artery disease (CAD) and type 2 diabetes in the Malmö Diet and Cancer Cohort (n = 25,369). Using cox proportional hazards models, we separately modelled the effect of plain and total (all water, including from food) water on CAD and type 2 diabetes risk, whilst adjusti

Terahertz permittivity parameters of monoclinic single crystal lutetium oxyorthosilicate

The anisotropic permittivity parameters of monoclinic single crystal lutetium oxyorthosilicate, Lu2SiO5 (LSO), have been determined in the terahertz spectral range. Using terahertz generalized spectroscopic ellipsometry (THz-GSE), we obtained the THz permittivities along the a, b, and c ⋆ crystal directions, which correspond to the ϵ a , ϵ b , and ϵ c ⋆ on-diagonal tensor elements. The associated

Diagnostic Accuracy of the Swedish Version of the Multicultural Cognitive Examination for Cognitive Assessment in Swedish Memory Clinics

Background: Cognitive assessment for foreign-born individuals is suboptimal. The Multicultural Cognitive Examination (MCE) was developed for use in culturally, linguistically and educationally diverse populations. The MCE includes the Rowland Universal Dementia Assessment Scale (RUDAS) and performs assessment of memory, verbal fluency, and visuospatial function. Objective: To compare the psychomet