This thesis covers aspects of the mature human B cell and its different guises on its way to become a fully differentiated antibody forming plasma cell (AFC), the key player in the humoral immune system. The understanding of the complex molecular mechanisms taking place in the B cell, as it first encounters antigen, enters the germinal center (GC) reaction, giving rise to memory cells and plasma c

The nineteenth century’s long term planning and successive construction of new burial grounds and new ways of burial, with the help of among others scientific, technical and ideological strategies, have been quite successful in institutionalising a consciousness of what a proper place of death should be like. For the architect Augustus Welby Pugin the promotion of a revival of the Gothic style in

The genetic systems in mitochondria and plastids differ both structurally and functionally from the nuclear genome and its gene expression. On the other hand, mitochondria share several genetic features with bacteria. For example, several genes are transcribed together and the ribosomes are of a prokaryotic type. This is in line with the evolutionary origin of the mitochondrion as an endosymbiont

29 sermons for the celebration of the Norwegian St. Olof/Olaf (July 29) have been preserved in medieval manuscripts of Swedish provenance. 27 of these were composed by friars of Vadstena Abbey. The article discusses what they tell us about the Saint, what sources the preachers used, and which characteristics of the Saint they emphasize. Finally, the main contents of a sermon on St. Olaf by the Vad

This thesis concerns paragraph 30, 31 and 32 of the Consumer Insurance Act. The Consumer Insurane Act was adopted in 1981. It is applicable to combined insurance policies covering fire, burglery, liability, and certain other risks when the insured party is a consumer. In these cases, the Consumer Insurance Act is applicable to motor vehicle-, yachting- and travelling insurance contracts as well.

Abstract is not available

The only proven genetic risk factor for Chronic Obstructive Pulmonary Disease (COPD) is an inherited Z (Glu342¡úLys) deficiency of alpha-1-antitrypsin (AAT), a major inhibitor of neutrophil elastase. In vivo, AAT is found in both native (inhibitory) and modified (non-inhibitory) forms. There is now increasing evidence that the different forms of AAT may exhibit biological activities independent of

This paper presents a method for translation of Java bytecode sequences into synthesizable hardware, using the Bluespec System Verilog (BSV) environment. At the core of our approach lies a BSV description of a subset of Java bytecodes, that can be used to directly translate bytecode sequences into a BSV specification. The result is intended as an accelerator for existing Java processors (JOP, Blue

Öppna digitala lärresurser (Open Educational Resources - OER) är resurser som finns tillgängliga på Internet och som kan användas fritt och i många fall också bearbetas fritt. Universitet världen över lägger ut sitt kursmaterial fritt på nätet, t ex MIT, Stanford och Open University. Lunds universitet har nyligen skapat en egen YouTube kanal och kommer snart att finnas på iTunesU och blir alltmer

Håller Sverige på att glida isär, fragmenteras eller är sprickorna i välfärden få och begränsade? Det är svårt att bortse från att de senaste 30 årens utveckling har inneburit stora förändringar i den välfärdsstat som utvecklades främst efter andra världskriget. I vissa avseenden har skyddsnäten blivit glesare. Utvecklingen har varit särskilt markant efter den ekonomiska krisen i början av 1990-ta

Popular Abstract in Swedish Grupp A streptokocker är bakterier som orsakar halsfluss, svinkoppor och rosfeber. Även allvarligare sjukdomstillstånd kan följa, t ex toxiskt schocksyndrom och nekrotiserande fasciit, som ibland har dödlig utgång. En annan vanlig bakterie är pneumokocken, som ger upphov till lunginflammation, mellanöreinflammation och hjärnhinneinflammation. Dessa vanliga bakterier utgDespite the availability of antibiotics and modern health care, infectious diseases continue to cause great suffering and costs. Bacterial surface proteins are important for the interaction between host and pathogen. This thesis gives an overview of the importance of bacterial surface proteins in Gram-positive bacteria, particularly Streptococcus pneumoniae and Streptococcus pyogenes. A novel cont