Search results

Background:Support, Monitoring, and Reminder Technology for Mild Dementia (SMART4MD), a customized tablet app, was developed to improve or maintain the quality of life of people with mild cognitive impairment (MCI) and their informal caregivers.Objective:This study conducts an 18-month economic evaluation of the SMART4MD app, in addition to standard care, compared with standard care alone in Swede

Does the human animal have an exclusive access to the realm of religious devo-tion? While both scholars and scientists are beginning to speak of and recognizeagency among nonhuman species, we have yet to explore the field of nonhumanreligiosity. The following article takes a first step in this direction by exploringhow especially Ambrose of Milan, in his Hexaemeron sermons, ascribed religiousagenc

Abstract in FrenchL’architecture éminente scandinave à la fin du Moyen-Âge sur terre et en mer. Une étude spatiale du château de Glimmingehus et du navire de guerre Gribshunden Par MARTIN HANSSON et BRENDAN FOLEYCe papier compare l’utilisation sociale de l’espace dans les châteaux et les navires de guerre à la fin du Moyen-Âge. Les principales études de cas utilisées sont le château de GlimmingehuTHIS PAPER COMPARES THE SOCIAL USE OF SPACE in late-medieval castles and warships. The main case studies used are the noble castle of Glimmingehus in present-day Sweden, built 1499 to 1505, and the royal warship Gribshunden, in use from the mid-1480s until its sinking in 1495; we also refer to the later and fully excavated warships Mary Rose and Vasa. Both castles and warships are examples of elit

The proline-rich domain (PRD) of the tumor suppressor p53 plays a central role in modulating conformational dynamics and molecular interactions, yet its intrinsic structural behavior remains incompletely understood. Here, we combine extensive all-atom molecular dynamics simulations with biophysical validation to characterize the conformational ensemble of the p53 PRD. The domain behaves as an intr

OBJECTIVE: To evaluate the association between metformin use and incident osteoarthritis (OA) in people with diabetes and the impact of dosing. DESIGN: Nested case-control study within a cohort of >1.4 million individuals from Sweden. PARTICIPANTS: Participants were aged 35-80 years in 2005, without diabetes or OA. We identified persons with incident diabetes between 2006 and 2016 and excluded tho

Immunoglobulin G subclass deficiencies (IgGSD) are associated with recurrent respiratory tract infections. Tools to identify patients with IgGSD who benefit from immunoglobulin G replacement therapy (IgGRT) are lacking. This crossover study evaluated the number of antibiotic-demanding infections on and after up to 18 mo off IgGRT in 28 patients with IgGSD. Pneumococcal antibodies against 21 seroty

This chapter explores the links between climate change, environmental degradation, and protracted armed conflicts, focusing on how international law can facilitate effective environmental interventions. It examines how international law, particularly the work of the UN International Law Commission on the Protection of the Environment in relation to Armed Conflicts (PERAC) Principles, international

Introduction: Ultra-severe traumatic brain injury (us-TBI), defined as Glasgow Coma Scale score (GCS) of five-three, is associated with high mortality and severe morbidity amongst survivors. However, in selected patients a favourable recovery may still be achieved. Research question: We aimed to characterise what clinical parameters can be used as prognosticators in us-TBI patients. Material and m

AIMS: To investigate the prevalence of diastolic dysfunction and associated risk factors in pre-diabetes and diabetes in the general population.METHODS: Diastolic function was assessed by transthoracic echocardiography in a cross-sectional sample of 3840 men and women aged 50-64 years from the Swedish CArdioPulmonary bioImage Study. Anthropometry, medical history, blood pressure, biochemistry and

Background: Photon-counting computed tomography (PCCT) is an emerging technique under evaluation for temporal bone imaging. Its capacity for radiation dose reduction while maintaining diagnostic image quality (IQ) requires further study. Purpose: To evaluate how PCCT compares to energy-integrating CT (EICT) in temporal bone imaging in terms of IQ and visualization of anatomical landmarks, at a cli

Background Carotid and coronary atherosclerosis are critical determinants of cardiovascular risk, yet their interrelationship in middle-aged populations is incompletely understood. This study assessed carotid plaque composition, risk-factor associations, coronary disease, and sex differences in a subclinical cohort. Methods Within the Swedish CArdioPulmonary bioImage Study, 533 asymptomatic indivi

Despite its promise, biodiesel production via the supercritical methanol (SCM) process has stalled due to limited understanding of interactions among key operating parameters and process-modeling gaps, resulting in contradictory techno-economic (TEA) and life-cycle carbon footprint assessments. In the present study, we integrate experimental optimization with techno-economic, carbon footprint, and

Environmental peacebuilding has emerged as an interdisciplinary field that integrates environmental governance with conflict resolution and post-conflict recovery. This chapter argues that this emerging field should be understood as a new paradigm in international law in two respects. First, it is a paradigm of legal ordering. In the absence of a single coherent regime for post-conflict environmen

Introduction: Long-term pelvic floor symptoms after childbirth may impair women's quality of life. The aim of this study was to assess the prevalence of self-reported pelvic floor symptoms 1 year postpartum in primiparous women by degree of perineal tear, with a focus on minor and major second-degree tears, and their association with quality of life. Material and Methods: This prospective cohort s

The unusually broad and intense visible (Vis) absorption band observed in naphthalenediimide–bithiophene (NDI-T2) co-polymers reflects complex electronic and vibronic interactions between donor and acceptor units. While the charge-transfer character arising from electronic coupling across the moieties likely contributes to the red-shifted absorption, the pronounced spectral broadness may also orig