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Clinical protein science and bioanalytical mass spectrometry with an emphasis on lung cancer
Detecting region transitions for human augmented mapping
In this paper, we describe a concise method for the feature-based representation of regions in an indoor environment and show how it can also be applied for door-passage-independent detection of transitions between regions to improve communication with a human user.
Parental history and venous thromboembolism: a nationwide study of age and sex-specific familial risks in Sweden.
Background: The value of parental history as a risk indicator for venous thromboembolism (VTE) has not been determined in a nationwide setting. Objectives: This is the first nationwide study of age and sex specific familial VTE risks in offspring of parents hospitalized for VTE. Patients/Methods: The Swedish Multigeneration Register of 0-75-year-old subjects was linked to the Hospital Discharge Re
Reduction of greenhouse gas emissions by wood ash application to a Picea abies (L.) Karst. forest on a drained organic soil
Wood ash additions of 3.3 and 6.6 t ha(-1) reduced greenhouse gas (GHG) emissions from a spruce forest (Picea abies) on a minerotrophic drained organic soil. Emissions of carbon dioxide (CO(2)), methane (CH(4)) and nitrous oxide (N(2)O) were measured using static dark chambers for two years following the ash treatment. The CO(2) emission from the soil was significantly reduced by 17-23% by both do
The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of A beta in different brain regions
Early-onset dominantly inherited forms of Alzheimer's disease (AD) are rare, but studies of such cases have revealed important information about the disease mechanisms. Importantly, mutations in amyloid precursor protein (APP), presenilin 1 (PSEN1) and PSEN2, alter the APP processing and lead to an increased amyloid beta-peptide (A beta) 42/40 ratio. This, together with other studies on pathogenic
Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function.
BACKGROUND AND AIMS: A pre-treatment determination of the thiopurine S-methyltransferase (TPMT) genotype or phenotype can identify patients at risk of developing severe adverse reactions from thiopurine treatment. The risk of misclassifying a patient might be dependent on the method used. The aim of this study was to investigate the concordance between TPMT genotyping and phenotyping. METHODS: T
Visual navigation in starfish: first evidence for the use of vision and eyes in starfish.
Most known starfish species possess a compound eye at the tip of each arm, which, except for the lack of true optics, resembles an arthropod compound eye. Although these compound eyes have been known for about two centuries, no visually guided behaviour has ever been directly associated with their presence. There are indications that they are involved in negative phototaxis but this may also be go
Hereditary Parkinson's Disease of Unknown Genetic Cause in Two Families from Southern Sweden
Forest water use and water use efficiency at elevated CO2: a model-data intercomparison at two contrasting temperate forest FACE sites
Predicted responses of transpiration to elevated atmospheric CO2 concentration (eCO2) are highly variable amongst process-based models. To better understand and constrain this variability amongst models, we conducted an intercomparison of 11 ecosystem models applied to data from two forest free-air CO2 enrichment (FACE) experiments at Duke University and Oak Ridge National Laboratory. We analysed
Learning about Climate Change: Finance Ministries in International Climate Change Politics
In the course of the last four years, finance ministries have increasingly been involved in the international climate change negotiations. The involvement has to a large degree been due to the framing of climate change as a market failure. The framing calls for an active climate change policy and has therefore been at odds with the framing of climate change policy previously predominant in finance
Recovery of struvite via coagulation and flocculation using natural compounds
One of the major setbacks of struvite recovery processes is the difficulty in harvesting struvite crystals. This study evaluates the use of different coagulants to improve precipitation of struvite (MgNH (4)PO(4)6H(2)O) crystals. Chitosan and poly(diallyldimethyl ammonium chloride) (Poly-DADMAC) as a coagulant-flocculent and alginate and bentonite as a coagulant aid have been examined in jar tests
The effect of intra- and inter-regional labour mobility on plant performance in Denmark: the significance of related labour inflows
This article investigates the impact of labour mobility on plant performance in Denmark. Our study shows that the effect of labour mobility can only be assessed when one accounts for the type of skills that flow into the plant and the degree to which these match the existing skills at the plant level. As expected, we found that the inflow of skills that are related to skills in the plant impacts p
Collaboration for transformation
The quinoline-3-carboxamide paquinimod (ABR-215757) reduces leukocyte recruitment during sterile inflammation: Leukocyte- and context-specific effects.
Quinoline-3-carboxamides (Q-compounds) are currently in clinical development for both autoimmune disease and cancer. We have previously shown that the Q-compound paquinimod (ABR-215757) significantly ameliorates disease symptoms in several mouse models of human inflammatory disease. Considering that recruitment of inflammatory cells into tissue is a common denominator of these models, we have in t
Masses, decay constants and electromagnetic form-factors with twisted boundary conditions
Using Chiral Perturbation Theory at one-loop we analyze the consequences of twisted boundary conditions. We point out that due to the broken Lorentz and reflection symmetry a number of unexpected terms show up in the expressions. We explicitly discuss the pseudo-scalar octet masses, axial-vector and pseudo-scalar decay constants and electromagnetic form-factors. We show how the Ward identities are
Patients With Knee Osteoarthritis Have a Phenotype With Higher Bone Mass, Higher Fat Mass, and Lower Lean Body Mass.
Although knee osteoarthritis (OA) is common, its etiology is poorly understood. Specifically, it is not known whether knee OA is associated with abnormal anthropometric and musculoskeletal characteristics known to be associated with OA in general. We recently studied this topic for patients with hip arthritis; however, it is important to evaluate it for knee OA separately, because there are report
Tighter Relaxations for Higher-Order Models based on Generalized Roof Duality
Many problems in computer vision can be turned into a large-scale boolean optimization problem, which is in general NP-hard. In this paper, we further develop one of the most successful approaches, namely roof duality, for approximately solving such problems for higher-order models. Two new methods that can be applied independently or in combination are investigated. The first one is based on cons
Distinct patterns of gained chromosomes in high hyperdiploid acute lymphoblastic leukemia with t(1;19)(q23;p13), t(9;22)(q34;q22) or MLL rearrangements.
Short term exposure to low amounts of airway irritants in a swine confinement building and inflammatory markers in blood and exhaled air.
Introduction and objective. Swine confinement buildings are known to contain large concentrations of airway irritants, and a number of studies have shown acute inflammatory effects in previously unexposed subjects when introduced to the environment in such buildings. However, studies comparing different methods of assessing such reactions are lacking, and it is not known if a measurable response c