Popular Abstract in Swedish Forskning kring biomarkörer har revolutionerat cancersjukvården. Några av de mest kända exemplen är PSA-testet som kan användas för att identifiera patienter med ökad risk för prostata cancer eller de nya antikroppsbehandlingarna, t.ex mot HER2 (trastuzumab/Hercepin) eller CD20 (rituximab/Rituxan), som gör att man nu ofta kan förlänga eller bota patienter som tidigare hThe goal of biomarker discovery is to identify disease defining molecules, which could be used to improve early detection and/or to predict survival and response to treatment. This thesis is about the transcription factor SOX11, a protein discovered in the context of mantle cell lymphoma in 2008, which shows great potential to be used as a clinical relevant biomarker. The aim of this thesis is to

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Forskningscirkel om handelsanställdas förbund inför Handels 100 år.

Abstract in UndeterminedSubject-specific finite element models have been used to predict stress-state and fracture risk in individual patients. While many studies analysed quasi-axial loading configurations, only few works simulated sideways load configurations, such as those arising in a fall. The majority among these latter directly predicted bone strength, without assessing elastic strain predi

The lichen flora of the Nordic countries, containing about 2000 species, is regarded as one of the best known in the world. Lichenological research of the region has been continuous since the days of Erik Acharius (1757–1819), the ”father of lichenology”, but it is a sad fact that there is no modern flora treatment of the region's impressive lichen flora, the last attempt in the 1870s being that o

Popular Abstract in Swedish The Third Gospel for the First Time beskriver en förstagångsupplevelse av Lukasevangeliet, en uppläsning inför adressaten Teofilus vänner, vid ett tillfälle då evangeliet var nyskrivet. Den förutsätter att någon av Teofilus vänner kände till antika biografier och uppfattade Lukasevangeliet som en sådan. Dessutom hade han fått en grundläggande undervisning om den kristnaIf Luke’s first audience understood the Gospel as a biography, what would their experience of the text have been? This book invites the reader to accompany the first readers or hearers of Luke’s Gospel and to experience the narrative about the life of Jesus alongside them. It utilises Wolfgang Iser’s theory about reading and readers and focuses on gaps and vacancies in the text. The most important

Energy security has become a key priority in EU policy but climate change mitigation commitments live on in parallel. The purpose of this paper is to analyse the extent to which EU climate change mitigation policies and energy security policies are coherent – a relationship that is far from clear cut since both areas are both complex and wide ranging. We use a simple policy-analytical framework fo

Hösten 2008 startade Nationella forskarskolan i socialt arbete (RSSW), som ett samarbete mellan de lärosäten som ger forskarutbildning i ämnet. I den här rapporten beskrivs doktorandgruppen i socialt arbete och doktorandernas eventuella erfarenheter av deltagande i forskarskolans kurser.

This thesis deals with processes coupled to injury in the peripheral nervous system (PNS), with a general aim to investigate the role of phospholipase A2 (PLA2) enzymes in axonal outgrowth. The axonal outgrowth of dorsal root ganglia (DRG) neurons in vitro was reduced by several different inhibitors of PLA2 activity and enhanced by an activator of this enzyme. The PLA2 inhibitors acted locally in