TNP-470 is an acknowledged anti-angiogenic factor, and was studied clinically as an anti-cancer drug. We previously reported on an additional property of this molecule: the intracellular generation of reactive oxygen species in B16F10 melanoma cells. We showed that a massive generation of ROS occurred in the first few hours after treatment with TNP-470 and that this event was critical to subsequen

Popular Abstract in Swedish Vanligt viloelektrokardiogram (EKG) med 12 avledningar är ett av de mest använda redskapen för diagnostik av hjärtsjukdom. Tidigare forskning har visat att detta EKG ej är optimalt, men att nya EKG-metoder kan ge viktig tilläggsinformation. En metod som i flera tidigare studier visat sig innehålla diagnostisk potential är analys av de högfrekventa signalkomponenterna i The standard 12-lead electrocardiogram (ECG) is one of the most commonly used methods for diagnosing heart disease. Standard ECG is not always optimal, however, and new ECG methods can provide additional information. Analysis of high-frequency QRS components (HF-QRS) has been shown to increase the diagnostic performance of the ECG. Since the amplitudes of the HF-QRS are low compared with those vis

A new immunoassay for the detection of hepatitis C core antigen (HCVcoreAg) in peripheral blood during serological window-phase was evaluated among healthy blood donors, commercially available hepatitis C virus (HCV) seroconversion panels and in-house specimens from individuals undergoing seroconversion. Among 1964 low-risk blood donor samples, seven samples were initially reactive but only one wa

Background and Objectives Reagent red blood cells (RBCs) for antibody detection should express certain important antigens as a double dose, that is, the donors must be homozygous for the corresponding alleles. Traditionally, dose is determined by serological typing and known allele frequencies. However, RHD zygosity cannot be predicted serologically owing to the absence of an antithetical antigen,

We discuss LS-forbidden Delta S = 2 transitions of Fe Pi that appear as strong lines in ultraviolet stellar and laboratory spectra. The lines occur because of indirect lever mixing-two close energy levels, w(2)P(3/2) and x(6)P(3/2), are mixed through a third level acting as a catalyst. In transition multiplets, that involve either the w(2)P(3/2) or the x(6)P(3/2) level the normal component is acco

A non-iterative time-domain method for solving the inverse scattering problem for the temporally dispersive, linear, homogeneous, and bi-isotropic slab at normal incidence is presented. The inverse scattering problem is to determine (finite time traces of) the susceptibility kernels of the medium given (finite time traces of) the reflection and transmission kernels, which are obtained by deconvolu

Data avseende bakgrund, sjukdomsbild; både fysisk och psykisk med data hämtades ur ADAD och DOK och genom intervjuer, social- och sjukvårdsjournaler i ett konsekutivt material om 216 klienter som vårdats på Lunden mellan januari 1997 till juni 2000. Totalt 115 flickor/kvinnor (80 LVM- och 52 LVU-flickor) testades med två test BCT och CMPS, psykiska symtom (SCL-90) och personlighetsstörning enligt

The reactions between chalcocite, synthetic copper(I) sulfide, acanthite and synthetic silver(I) sulfide, and aqueous and acetone solutions of potassium ethylxanthate have been studied. Qualitative analysis of the ethylxanthate species present on the surfaces of the sulfide minerals and the synthetic metal sulfides has been made by means of diffuse reflectance infrared Fourier transform (DRIFT) sp

This thesis concerns two interrelated subjects of heat and mass transfer processes. The first one concerns mainly experimental measurements, with a subsequent development of a calculation procedure, of the thermal and hydraulic performances, experimental methods and evaluation procedures applied on various plate heat exchangers (PHEs) as evaporators with the refrigerant ammonia as working medium.

This study examines the determinants behind the restructuring of China's SOEs in the late 1990s. We have reached two major findings. First, we find that the degree of labor retrenchment is negatively related to enterprise performance, suggesting that poor performance is a major force driving labor restructuring. Second, we offer evidence that decisions on labor retrenchment in traditional SOEs are

NADH:quinone oxidoreductase, or Complex I, is a multi-subunit membrane-bound enzyme in the respiratory chain of many pro- and eukaryotes. The enzyme catalyzes the oxidation of NADH and donates electrons to the quinone pool, coupled to proton translocation across the membrane, but the mechanism of energy transduction is not understood. In bacteria the enzyme consists of 14 subunits, seven membrane

Artikeln bygger på föredrag som hållits i Göteborg, Oslo, Malmö och Torpa. Den hävdar att såväl ”Bibelsyn och bibelbruk” som dess opponenter stannat vid bibelsynen utan att egentligen behandla bibelns bruk i kyrkan och hos den enskilde. I Giertz författarskap – med tonvikt på de historiska romanerna Stengrunden, Tron allena, och Riddarna på Rhodos – är däremot Bibelns bruk av central och avgörande