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Scapular osseous free flap in head and neck reconstruction : An assessment of the postoperative function of the donor site

Background: The scapular osseous free flap (SOFF) has become an important reconstructive option for complex head and neck defects. Postoperative donor site function is, however, an important consideration. The objective of this study was to prospectively investigate SOFF donor site morbidity and to relate the findings to hand dominance and neck dissection. Methods: Objective assessment included bi

Revisiting the Concrete Security of Goldreich's Pseudorandom Generator

Local pseudorandom generators are a class of fundamental cryptographic primitives having very broad applications in theoretical cryptography. Following Couteau et al.’s work at ASIACRYPT 2018, this paper further studies the concrete security of one important class of local pseudorandom generators, i.e., Goldreich’s pseudorandom generators. Our first attack is of the guess-and

Gender-Based Differences and Associated Factors Surrounding Excessive Smartphone Use Among Adolescents: Cross-sectional Study

Background: Excessive smartphone use is a new and debated phenomenon frequently mentioned in the context of behavioral addiction, showing both shared and distinct traits when compared to pathological gaming and gambling. Objective: The aim of this study is to describe excessive smartphone use and associated factors among adolescents, focusing on comparisons between boys and girls. Methods: This st

Large-eddy simulation of the injection timing effects on the dual-fuel spray flame

Large-eddy simulations (LES) coupled with a partially-stirred reactor model and a finite-rate chemistry are carried out to investigate the effects of n-heptane injection timing on the methanol fueled dual-fuel (DF) combustion. Methanol is premixed with air in a constant volume chamber (T=1000 K, ρ=14.8 kg/m3) to form a homogeneous mixture (equivalence ratio ϕm of 0.3). Liquid fuel n-heptane is pro

External validation of postoperative pancreatic fistula prediction scores in pancreatoduodenectomy : a systematic review and meta-analysis

Background: Multiple risk scores claim to predict the probability of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy. It is unclear which scores have undergone external validation and are the most accurate. The aim of this study was to identify risk scores for POPF, and assess the clinical validity of these scores. Methods: Areas under receiving operator characteristic curve (A

Displacement Patterns in Magnetomotive Ultrasound Explored by Finite Element Analysis

Magnetomotive ultrasound is an emerging technique that enables detection of magnetic nanoparticles. This has implications for ultrasound molecular imaging, and potentially addresses clinical needs regarding determination of metastatic infiltration of the lymphatic system. Contrast is achieved by a time-varying magnetic field that sets nanoparticle-laden regions in motion. This motion is governed b

Analys och värdering av räddningstjänstens operativa förmåga

Att analysera och värdera räddningstjänstens operativa förmåga är nödvändigt för att tydligt och transparent kunna dimensionera verksamheten. I den här rapporten presenterar vi ett förslag på hur sådana analyser och värderingar kan genomföras med fokus på skydd mot olyckor och kommunal räddningstjänst. Rapporten är framtagen på uppdrag av Malmö stad och Lunds kommun, vilket innebär att den data so

Milk intake and incident stroke and coronary heart disease in populations of European descent : A Mendelian Randomization study

Higher milk intake has been associated with a lower stroke risk, but not with risk of coronary heart disease (CHD). Residual confounding or reverse causation cannot be excluded. Therefore, we estimated the causal association of milk consumption with stroke and CHD risk through instrumental variable (IV) and gene-outcome analyses. IV analysis included 29,328 participants (4,611 stroke; 9,828 CHD) o

Simple diameter measurements with ultrasound can be safely used to follow the majority of patients after infrarenal endovascular aneurysm repair

Background: The optimal imaging follow-up after infrarenal EVAR is still undefined. The aim of this study was to analyze the outcome of a personalized follow-up program after infrarenal EVAR based on ultrasound AAA diameter measurements for low-risk patients. Methods: All consecutive patients followed-up locally after elective and acute infrarenal EVAR between 2010 and 2015 were retrospectively re

Nonmonotonic Reasoning, Expectations Orderings, and Conceptual Spaces

In Gärdenfors and Makinson (Artif Intell 65(2):197–245, 1994) and Gärdenfors (Knowledge representation and reasoning under uncertainty, Springer-Verlag, 1992) it was shown that it is possible to model nonmonotonic inference using a classical consequence relation plus an expectation-based ordering of formulas. In this article, we argue that this framework can be significantly enriched by adopting a

The effects and possible mechanism of action of apolipoprotein M on the growth of breast cancer cells

Background: To investigate the effects and mechanism of action of apolipoprotein M (ApoM) on the growth of breast cancer (BC) cells. Methods and results: Bioinformatics, cell experiments and animal experiments were used to verify the effect of ApoM on breast cancer cell lines and breast tumor growth in vivo. ApoM expression was significantly reduced in BC tissues, and patients with lower ApoM mRNA

Pre- and Postnatal Maturation are Important for Fentanyl Exposure in Preterm and Term Newborns : A Pooled Population Pharmacokinetic Study

Background and Objective: Fentanyl is an opioid commonly used to prevent and treat severe pain in neonates; however, its use is off label and mostly based on bodyweight. Given the limited pharmacokinetic information across the entire neonatal age range, we characterized the pharmacokinetics of fentanyl across preterm and term neonates to individualize dosing. Methods: We pooled data from two previ

Effects of pin fins and vortex generators on thermal performance in a microchannel with Al2O3 nanofluids

This paper performs a comparative analysis to obtain the optimal cross-section shape and parameters of both pin fins and vortex generators. A novel combined structure with pin fins and vortex generators is proposed to enhance thermal performance of an integrated microchannel heat sink. Effects of nanoparticle diameter and volume fraction are investigated using Al2O3 nanofluid and DI-water as worki

ICF Core Sets for the assessment of functioning of adults with cerebral palsy

Aim: To report on the results of the online international consensus process to develop the comprehensive and brief International Classification of Functioning, Disability and Health (ICF) Core Sets for adults with cerebral palsy (CP). Method: An online iterative decision-making and consensus process involved 25 experts, including clinicians and researchers working with adults with CP, an adult wit

Shared genetic and environmental etiology between substance use disorders and suicidal behavior

Background Previous studies have demonstrated substantial associations between substance use disorders (SUD) and suicidal behavior. The current study empirically assesses the extent to which shared genetic and/or environmental factors contribute to associations between alcohol use disorders (AUD) or drug use disorders (DUD) and suicidal behavior, including attempts and death. Methods The authors u

Transposable elements mark a repeat-rich region associated with migratory phenotypes of willow warblers (Phylloscopus trochilus)

The genetic basis of bird migration has been the focus of several studies. Two willow warbler subspecies (Phylloscopus trochilus trochilus and Phylloscopus trochilus acredula) follow different migratory routes to wintering grounds in Africa. Their breeding populations overlap in contact areas or “migratory divides” located in central Scandinavia and in eastern Poland. Earlier analyses demonstrated

We can’t let markets decide the future of removing carbon from the atmosphere

Net zero emission pledges by countries and companies are everywhere at the moment. Most of these pledges rely on massive amounts of carbon removal, yet details on how this will transpire remain largely absent. The COP26 agreement suggests that markets will play a central role, but there are significant problems with this approach.