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2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)-acetamide labeled with [F-18]-fluorine ([F-18]EF5), a promising tracer for tumor hypoxia, has previously been synthesized in low yields and low specific radioactivity. In pharmacokinetic evaluations, in the presence of non-radioactive EF5, a uniform and low background uptake and high in vivo stability of [F-18]EF5 have been demonstrated.
The Bayan Har Shan, a prominent upland area in the northeastern sector of the Tibetan Plateau, hosts an extensive glacial geological record. To reconstruct its palaeoglaciology we have determined Be-10 exposure ages based on 67 samples from boulders, surface pebbles, and sediment sections in conjunction with studies of the glacial geology (remote sensing and field studies) and numerical glacier mo
Background: The aim of this study is to estimate ovarian volume, number and volume of antral follicles, and ovarian power Doppler vascular indices as assessed by three-dimensional (3D) transvaginal grayscale and power Doppler ultrasound in women using combined oral contraceptives (COC). Study Design: Two hundred thirteen gynecologically asymptomatic women 20-39 years old using COC were examined wi
BACKGROUND: Fetal exposure to maternal diabetes mellitus (DM) is associated with high birth weight, congenital heart malformations, childhood adiposity, DM, hypertension and dyslipidemia. The long term cardiovascular consequences of fetal exposure to maternal DM during pregnancy and high birth weight are not known. METHOD: All individuals born in Sweden 1973-1988 (n=1,551,603) were included in the
In a gravel pit near Hultsfred, at the eastern margin of the South Swedish Upland, gravelly, sandy and silty-sandy beds covered by a thick, stratified gravelly diamicton are exposed. Large folds and shear-planes indicate post-depositional deformation of the sorted sediments, which according to OSL dating have a maximum Middle Weichselian (60ka) age. The sand and gravel are interpreted as glacioflu
Mediated mega-events are essentially projects of belonging: about imagining communities and about creating attachment to such collective selves. However, events like the Olympic Games are not only an opportunity for states to reinforce official constructions of belonging but can also be sites for the articulation and dissemination of contesting identity narratives. This article investigates Russia
The macroscopic phase behavior and other physicochemical properties of dilute aqueous mixtures of DNA and the cationic surfactant hexadecyltrimethylammounium bromide (CTAB), DNA and the polyamine spermine, or DNA, CTAB, and (2-hydroxypropyl)-β-cyclodextrin (2HPβCD) were investigated. When DNA is mixed with CTAB we found, with increasing surfactant concentration, (1) free DNA coexisting with surfac
Radiative lifetimes of 17 excited levels of Nb i, in the energy range 27 400-47 700 cm-1 (5p y 6D degrees(9/2), 5p x 6D degrees(7/2), 5p w 4G degrees(7/2,9/2,11/2), 5s5p v 4D degrees(1/2,3/2,5/2,7/2), 5s6p n 4D degrees(1/2,3/2,5/2,7/2), 5s6p o 4F degrees(3/2,5/2,7/2,9/2)), have been measured. For 15 of these levels, the lifetimes are obtained for the first time. The lifetimes were measured using t
We examined oxygen three-isotope ratios of 48 extraterrestrial chromite (EC) grains extracted from mid-Ordovician sediments from two different locations in Sweden, and one location in south-central China. The ages of the sediments (similar to 470 Ma) coincide with the breakup event of the L chondrite parent asteroid. Elemental compositions of the chromite grains are generally consistent with their
In this work, influence of hydrogen and temperature on the fracture toughness parameters of unirradiated, cold worked and stress relieved (CWSR) Zr-2.5Nb pressure tube alloys used in Indian Pressurized Heavy Water Reactor is reported. The fracture toughness tests were carried out using 17 mm width curved compact tension specimens machined from gaseously hydrogen charged tube-sections. Metallograph
Recent research in entrepreneurship has examined factors that could reduce the challenges facing new businesses (the so-called ‘liabilities of newness’). Seeking to contribute to this research, this study examines the potential role of a financial bootstrapping approach (finding ways of securing resources on favourable terms). Even though financial bootstrapping has received increased attention in
Climate change (CC) is one of the major and most encompassing threats in the world today. While the facts and high-consensus predictions among natural scientists are increasingly well-known, the understanding of CC as a socio-ecological issue is much less clear and uncontroversial. This paper summarizes the available climate science expertise and then discusses the genesis of CC as a socio-ecologi
Each fall, eastern North American monarch butterflies (Danaus plexippus) use a time-compensated sun compass to migrate to their overwintering grounds in central Mexico. The sun compass mechanism involves the neural integration of skylight cues with timing information from circadian clocks to maintain a constant heading. The neuronal substrates for the necessary interactions between compass neurons
Removal of six active pharmaceutical ingredients in wastewater was investigated using chlorine dioxide (ClO2) or peracetic acid (PAA) as chemical oxidants. Four non-steroidal anti-inflammatory drugs (ibuprofen, naproxen, diclofenac and mefenamic acid) and two lipid-regulating agents (gemfibrozil and clofibric acid, a metabolite of clofibrate) were used as target substances at 40 mu g/L initial con
We present the description of the exponentiated diagrams in terms of generating function within the universal diagrammatic technique. In particular, we show the exponentiation of the gauge theory amplitudes involving products of an arbitrary number of Wilson lines of arbitrary shapes, which generalizes the concept of web diagrams. The presented method gives a new viewpoint on the web diagrams and
Spectral measurements of visible coherent transition radiation produced by a laser-plasma-accelerated electron beam are reported. The significant periodic modulations that are observed in the spectrum result from the interference of transition radiation produced by multiple bunches of electrons. A Fourier analysis of the spectral interference fringes reveals that electrons are injected and acceler
We hypothesized that a targeted temperature of 33 °C as compared to that of 36 °C would increase survival and reduce the severity of circulatory shock in patients with shock on admission after out-of-hospital cardiac arrest (OHCA).
Vertical range-resolved measurements of atmospheric pollutants were performed in a major city in southern China, employing a lidar system operating with an optical parametric oscillator transmitter. Recordings of atomic mercury (Hg) and nitric oxide (NO) absorbing in the deep-UV region were taken, yielding concentration profiles only attainable with lidar techniques. In particular, the potential i
Product innovation in highly complex and technological areas, such as medical technology, puts high requirements on the innovation capability of an organisation. Previous research and publications have highlighted organisational issues and learning matters as important and necessary for the development of innovation capability. Action learning requires reflections of the ways things are carried ou
