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From nanoLEDs to the realization of RGB-emitting microLEDs

MicroLED technology is expected to be the technology of choice for next-generation displays. Its advantages in various applications are reviewed. The challenges of microLED manufacturing, including red microLED realization, adequate efficiency, mass transfer, and structure and process design from a system perspective, are discussed with a special emphasis on how nano-scale material science may ope

Quantum and Approximation Algorithms for Maximum Witnesses of Boolean Matrix Products

The problem of finding maximum (or minimum) witnesses of the Boolean product of two Boolean matrices (MW for short) has a number of important applications, in particular the all-pairs lowest common ancestor (LCA) problem in directed acyclic graphs (dags). The best known upper time-bound on the MW problem for n× n Boolean matrices of the form O(n2.575) has not been substantially improved since 2006

Politicization of EU Development Policy: The Role of External Perceptions (Case of Ukraine)

This article highlights the role of external audiences and their perceptions in analysing the politicization of EU development policy. We analyse how EU foreign assistance is understood in two different intermediary arenas of politicization – elites in different societal sectors and media – within Ukraine, a major recipient of EU aid. By investigating to what extent EU assistance is perceived to b

Spreading a Norm-based Policy? Sweden's Feminist Foreign Policy in International Media

Since 2014, Sweden has pursued the world's first Feminist Foreign Policy (FFP). However, the effectiveness of its policy promotion depends on how Sweden's efforts to spread this norm-based policy are perceived and evaluated by other states. We argue that a policy promotion effort has to be perceived as legitimate, coherent and salient by target populations in order to be effective. We investigate

Being, belonging, and borders : Scandinavian creation theology as political theology

Desire for life and protecting lives has come to the fore during the pandemic. Borders have been closed to stop the spread of Covid-19. The virus does not respect borders, yet physical distance is crucial. Three things have become clear. One is the level of uncertainty about which measures are most efficient. The other is that the neo-liberal philosophy with “just in time” deliveries on a global m

Randomized Phase II trial of combination chemotherapy with panitumumab or bevacizumab for patients with inoperable biliary tract cancer without KRAS exon 2 mutations

Biliary tract cancers (BTC) are rare and often diagnosed in late stages with advanced, nonresectable disease. The targeted agents panitumumab and bevacizumab have shown promising outcomes in combination with chemotherapy in other gastrointestinal (GI) cancers. We wanted to investigate if panitumumab or bevacizumab was the most promising drug to add to chemotherapy. Eighty-eight patients were rando

Swedish national guidelines for chronic pancreatitis

Chronic pancreatitis (CP) should be suspected in the case of recurrent upper abdominal pain of unknown origin and/or clinical signs of exocrine pancreatic insufficiency (EPI). Alcohol is the most common etiological factor associated with CP, others being smoking, male gender, and hereditary forms. CP is often associated with recurrent episodes of acute exacerbations. As of today, there is no accep

Risk-adapted starting age of breast cancer screening in women with a family history of ovarian or other cancers : A nationwide cohort study

BACKGROUND: There is a lack of evidence-based recommendations for the age at which women with a family history of cancers other than breast cancer should start breast cancer screening. METHODS: Using Swedish family cancer data sets, the authors conducted a nationwide cohort study including 5,099,172 Swedish women born after 1931 (follow-up, 1958-2015). Accounting for calendar time, they calculated

Identification, isolation and analysis of human gut-associated lymphoid tissues

Gut-associated lymphoid tissues (GALTs) comprise key intestinal immune inductive sites, including the Peyer’s patches of the small intestine and different types of isolated lymphoid follicle (ILF) found along the length of the gut. Our understanding of human GALT is limited due to a lack of protocols for their isolation. Here we describe a technique that, uniquely among intestinal cell isolation p

Sinonasal Symptoms and Self-Reported Health before and after Endoscopic Pituitary Surgery-A Prospective Study

Objectives Despite the limited invasiveness of endoscopic transsphenoidal surgery (ETSS), some degree of nasal structure destruction is unavoidable. Our objective was to evaluate sinonasal morbidity and self-reported health before and 6 months after ETSS for pituitary tumors, and to identify possible predictive factors for deterioration in sinonasal health. Design Prospective observational cohort

The generative relationship between job quality, innovation, and employment

Recent qualitative and quantitative research on the interrelationships between innovation, job quality and employment shows a strong association between job quality and product, process, and to a lesser extent organizational innovation. This is theorized as the interaction of two systems – job quality and innovation systems. Increased employment and improved job quality are found to result from inRecent qualitative and quantitative research on the interrelationships between innovation, job quality and employment shows a strong association between job quality and product, process, and to a lesser extent organizational innovation. This is theorized as the interaction of two systems – job quality and innovation systems. Increased employment and improved job quality are found to result from in

Abundances of disk and bulge giants from high-resolution optical spectra : IV. Zr, La, Ce, Eu

Context. Observations of the Galactic bulge suggest that the disk formed through secular evolution rather than gas dissipation and/or mergers, as previously believed. This would imply very similar chemistry in the disk and bulge. Some elements, such as the α-elements, are well studied in the bulge, but others like the neutron-capture elements are much less well explored. Stellar mass and metallici

The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms

Dermatan sulfate epimerase 1 (DS-epi1, EC 5.1.3.19) catalyzes the conversion of d-glucuronic acid to l-iduronic acid on the polymer level, a key step in the biosynthesis of the glycosaminoglycan dermatan sulfate. Here, we present the first crystal structure of the catalytic domains of DS-epi1, solved at 2.4 Å resolution, as well as a model of the full-length luminal protein obtained by a combinati

Multinodal Acoustic Trapping Enables High Capacity and High Throughput Enrichment of Extracellular Vesicles and Microparticles in miRNA and MS Proteomics Studies

We report a new design of an acoustophoretic trapping device with significantly increased capacity and throughput, compared to current commercial acoustic trapping systems. Acoustic trapping enables nanoparticle and extracellular vesicle (EV) enrichment without ultracentrifugation. Current commercial acoustic trapping technology uses an acoustic single-node resonance and typically operates at flow

Long-Haul Post–COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrome: The Swedish Experience

Major clinical centers in Sweden have witnessed an inflow of patients with chronic symptoms following initial outpatient care for coronavirus disease-2019 (COVID-19) infection, suggestive of postural orthostatic tachycardia syndrome. This report presents the first case series of 3 Swedish patients diagnosed with postural orthostatic tachycardia syndrome more than 3 months after the primary COVID-2