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Projekteffektivisering i ABB:s 800xA; Framtagning av labbmiljö och demosystem i ABB:s 800xA

Rapporten behandlar framtagningen av en labbmiljö i ABB:s 800xA. Labbmiljön ämnar effektivisera testning av Distributed Control Systems (DCS) och på så sätt effektivisera uppstarten och genomförandet av industriskaliga processystem. Konceptet för labbmiljön är att ge möjligheten att snabbt kunna sätta upp ett system i 800xA som kan användas till testning, processutveckling och kompetensutvecklingThe report deals with the development of a lab environment in ABB's 800xA. The lab environment aims to streamline the testing of Distributed Control Systems (DCS) and thus streamline the start-up and implementation of industrial-scale process systems. The concept of the lab environment is to provide the opportunity to quickly set up a system in 800xA that can be used for testing, process dev

Två fynd. Tre städer: En jämförande studie av tre arkeologiska utställningar

This thesis explores how different museums choose to present the same type of material. The study focuses on Anglo-Saxon material, from between 500 and 800 A.D. The exhibitions that have been selected deal with the Sutton Hoo ship burial, which is exhibited at the British Museum in London, and the Staffordshire Hoard, which has been exhibited both at the Birmingham Museum & Art Gallery and at

Wind power forecasting using random forests

The present thesis investigated using the random forest machine learning algorithm for wind power forecasting. Meteorological prognoses for wind speed, wind direction, gust winds, and humidity were used. For historical data, wind minimum and temperature was also included. The results were evaluated using root means square error (RMSE), mean absolute error (MAE), normalized mean absolute error (NMA

Visualizing Local Identity : Artistic Expression in the Post-2020 Hong Kong

Hong Kong’s art scene has been subject to relevant changes in recent years due to unprecedented events that characterised the years of 2019 and 2020 (large-scale protests, implementation of the National Security Law, and the Pandemic). These changes have affected the production and self-perception of local artists. In this thesis, a constructionist life story interview is used to investigate how t

Energy in the Transportation System - A comparison of charging infrastructure scenarios

A functioning charging infrastructure is crucial for achieving full-scale national electrification within the transport sector. The system is likely to consist of different charging technologies, all with the main objective of providing efficient energy replenishment services. Careful planning for the deployment of this infrastructure is of high importance. The consumer segments are diverse, each

Förutsättningar för existentiella samtal. En kvalitativ studie om kuratorernas upplevelse av samtal med patienter om existentiella frågor vid kvinnokliniken

The aim of the study was to examine how counselors at the women's clinic relate to existential questions in the meeting with patients related to social work in a healthcare setting. The intention was to look closer at what challenges the staff faces, as well as what they find obstacles that stop or make it difficult to talk about existential issues. This was investigated through semi-structure

Selective justice within the International Criminal Court and global inequalities

Afrikanska stater har nyligen hävdat att internationell rätt är i processen att förvandlas till en ny form av kolonialism och en hegemonisk makt vilket tidigare maskerats som the rule of law. I föreliggande avhandling undersöks Internationella brottmålsdomstolens partiskhet mot den tredje världens afrikanska stater, i samband med den mänskliga rättigheten till en rättvis rättegång. Avhandlingens öAfrican states have recently claimed that international law is transforming into a new form of colonialism and a hegemonic power masquerading as the international rule of law. The International Criminal Court's bias against the Third World African states in correlation to the human right to a fair trial is investigated. The thesis overarching question addresses the Court's selective justic

Generation and characterisation of human and non-human primate cerebral organoids for the study of transposable elements

Generering och karakterisering av hjärnorganoider från människa och primater för analys av hoppande gener Människans hjärna har under evolutionen ökat i storlek och har blivit betydligt mycket större än hjärnan hos våra närmaste levande släktingar, schimpanserna. Trots denna drastiska skillnad så delar vi ca 98% av våra proteinkodande DNA sekvenser med schimpanserna. Detta indikerar att förändrinDuring evolution the human brain has increased drastically in size compared to that of other primates. However, little is known about primate brain development as it is difficult to study human and primate brains in the laboratory due to the scarcity of tissues. Yet, it is essential to study primate brains and understand the molecular features leading to the human brain’s unique cognitive function

Virulence variation of Mycobacterium avium in myeloid cells

A better understanding of Mycobacterium avium for a better treatment? Nontuberculous mycobacteria (NTM) are common bacteria found in water and soil. They are opportunistic pathogens of humans and animals. Among them, a group called Mycobacterium avium complex (MAC) is a major cause of pulmonary diseases. These infections are very hard to treat and have high mortality rates. Mycobacterium avium is

Role of Tumor Suppressor protein CSMD1 along with its effect on Trastuzumab treatment in HER-2 positive Breast adenocarcinoma and its regulation by miRNAs in Gliomas

Background: Cancer, which is known for its high mortality rate, can affect several tissue types. Among these, breast cancer is the most prevalent form worldwide and gliomas has one of the highest mortality rates among all cancer types. CSMD1 is a complement inhibitor with known tumor suppressor properties, whose down-regulation and deletion has been identified in several cancer types. In this stud

Prime editing to correct disease causative mutations in patient-derived Gaucher iPSC lines

Prime editing to correct disease causative mutations in patient derived Gaucher iPSC lines Lysosomes are the recycling bins of our cells, but what happens if they stop working? Do we get sick? Why would they stop working? Dysfunctions in lysosomes can be due to genetic mutations, changes in our genome that can lead to brain disease and premature death. Recently, the CRISPR/Cas9 system, that works

Molecular and functional characterization of lung cancer initiating cells

Lung cancer is one of the most aggressive diseases in the whole world, claiming millions of people each year. Nobody has yet found a successful cure for it and, therefore, there is an urgent need for more research to discover how patients could be saved. Lung cancer is so hard to diagnose since it grows quietly and it’s often detected when it has spread to other organs, meaning that it has invaded

Investigating RNA toxicity using sister sRNAs OmrA & OmrB

Bacteria have harnessed a variety of self-acting toxic mechanisms to regulate plasmid maintenance, phage defense, expression of virulence factors, and antimicrobial resistance. It was thought that the expression of toxic proteins was the sole source of toxicity in bacteria. Recent studies have shown the potential for RNA to cause toxic growth phenotypes independent of toxic protein expression. How

Krishantering, beredskap och lärdomar av tsunamifallen vid Indiska Oceanen 2004 & Japan 2011 Förebyggande åtgärder för människor och bebyggelse

Krishantering och förebyggande arbete inför naturkatastrofer, som i detta examensarbete avgränsas till tsunamis, har identifierats som bristande genom tiderna. Här studeras tsunamikatastroferna i Indiska Oceanen 2004 och Japan 2011 för att identifiera brister hos varningssystemen som används för att skydda samhällena som befinner sig i dessa riskzoner och dess befolkning. Först visade det sig att

Understanding how endothelial cells affect necrotizing soft tissue infections using an in vitro organotypic soft tissue infection model

Köttätande bakterier – från ofarlig till livshotande Bakterier är små levande ting som inte är synliga för blotta ögat. Alla bakterier orsakar inte sjukdom och vissa bakterier gör det om de befinner sig på fel plats i din kropp. Köttätande bakterier har fått sitt namn från att dom gör att vävnad i kroppen dör och när det sker orsakar dessa bakterier en mycket sällsynt och livshotande infektion. I

Den samtida och framtida brassbandskompositionen

Den samtida och framtida brassbandskompositionen" är ett examensarbete som syftar till att, utifrån ett tonsättarperspektiv, undersöka musik som är komponerad för brassbandstävlingar och identifiera de komponenter som behövs i både komposition och instrumentation för att skapa såväl en konstnärlig produkt som tävlingsförutsättningar. För att genomföra detta har författaren Daniel Möllås - tiThe contemporary and future brass band composition" is a thesis which, from a composers point of view, aims to investigate music composed for brass band competitions and to identify the components needed in both composition and instrumentation, in order to create an artistic product as well as conditions for competing. To accomplish this, the author Daniel Möllås - also a composition student

Unravelling the Tensions; Impact of the Common Foreign and Security Policy of the EU on Fundamental Rights and the Intricacy of Freedom of Movement

The CFSP has become a focal point of legal and political analysis, particularly concerning its impact on fundamental rights and the free movement of capital. Departing from that situation, the thesis attempts to delve into the complex question as its research question to find out how the EU balance its collective interests in pursuing sanctions with national sovereignty, the fundamental rights of

Investigating Innate Tolerization of Myeloid Cells to Mycobacterium tuberculosis Glycolipids

Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (Mtb) remains a global health threat, claiming 1.6 million lives in 2021 alone and infecting an estimated quarter of the world’s population in a latent or controlled infection. Glycolipids make up a large part of the bacterial cell wall and closely interact with innate immune cells, influencing their response upon infection. Th

Examining the effects of MLC1 mutations in induced astrocytes and on development of neuroglia using cerebral organoids

Megalencephalic leukoencephalopathy with subcortical cysts (MLC), is a congenital leukodystrophy with childhood onset. It is an extremely rare genetic disorder of the brain that affects less than 1 per 1,000,000 live births. Patients typically present macrocephaly during early childhood and later develop symptoms like decreased motor and cognitive functions, and epileptic seizures, all of which us