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The Problems of Inflation Targeting Originate in the Monetary Theory of Knut Wicksell

The theoretical foundation of inflation targeting was laid out by the Swedish economist Knut Wicksell (1851-1926) in his groundbreaking treatise, Interest and Prices, published originally in German in 1898. Here he proposed price stability as the rule for monetary policy. Today, inflation targeting is considered the best-practice approach to monetary policy across the world. It has contributed to

Wanted : a low-carbon and fair reset

A piece about a just transition to a low-carbon future (contribution to UNESCO Inclusive Policy Lab 'Think pieces' that explores emerging issues in inclusive policies as well as offering cutting edge solutions).

App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden

The app-based COVID Symptom Study was launched in Sweden in April 2020 to contribute to real-time COVID-19 surveillance. We enrolled 143,531 study participants (≥18 years) who contributed 10.6 million daily symptom reports between April 29, 2020 and February 10, 2021. Here, we include data from 19,161 self-reported PCR tests to create a symptom-based model to estimate the individual probability of

Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema

Cerebral oedema develops after anoxic brain injury. In two models of asphyxial and asystolic cardiac arrest without resuscitation, we found that oedema develops shortly after anoxia secondary to terminal depolarizations and the abnormal entry of CSF. Oedema severity correlated with the availability of CSF with the age-dependent increase in CSF volume worsening the severity of oedema. Oedema was id

The Impact of Physical Distancing on the Evacuation of Crowds

One of the key implications of COVID-19 is the adoption of physical distancing provisions to minimise the risk of virus transmission. Physical distancing can have significant consequences on crowd movement both in normal conditions and during emergencies. The impact of physical distancing is discussed in this chapter by first presenting an overview of its implications on crowd dynamics and space u

Concept design of electric cruise and startability axles for long haul heavy vehicles to maximise driving range

Electrification of commercial heavy vehicles has led to the offer of different electric drive-based powertrain architectures, most of them with the adaptation of the diesel engine based architecture. Due to the limited driving range possible, optimal configuration of the powertrain becomes a vital task with the battery as the energy source, which also takes a significant portion of payload capacit

A Local Atomic Mechanism for Monoclinic-Tetragonal Phase Boundary Creation in Li-Doped Na0.5K0.5NbO3Ferroelectric Solid Solution

ABO3 perovskites display a wide range of phase transitions, which are driven by A/B-site centered polyhedral distortions and/or BO6 octahedral tilting. Since heterogeneous substitutions at the A/B-site can locally alter both polyhedral distortions and/or tilting, they are often used to create phase boundary regions in solid solutions of ABO3, where the functional properties are highly enhanced. Ho

A randomized phase II trial of efficacy and safety of the immunotherapy ALECSAT as an adjunct to radiotherapy and temozolomide for newly diagnosed glioblastoma

Background: There is an urgent need for effective treatments against glioblastoma (GBM). In this trial, we investigated the efficacy and safety of an adoptive cell-based immunotherapy. Methods: Patients with newly diagnosed GBM were recruited at 4 study sites in Sweden. The patients were randomized 1:2 to receive either radiotherapy (RT), 60 Gy/30 fractions, with concomitant and adjuvant temozolom

Protocol summary and statistical analysis plan for the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial

Background: Targeted therapeutic mild hypercapnia may attenuate brain injury in comatose adults resuscitated from out-of-hospital cardiac arrest. Objective: To describe the study protocol and statistical analysis plan for the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial. Design, setting, participants and interventions: TAME is a phase 3, multicentre, paralle

Effects of Particle Size and Mainstream Inlet Angle on Deposition in a Turbine Cascade

Based on the critical velocity model, impact and capture efficiencies in an AGTB turbine cascade are investigated numerically under various inlet angles of mainstream, blowing ratios, particle sizes, and particle densities. The effect of hole configuration on deposition is analyzed based on comparisons of results from combined hole and cylindrical hole. The impact efficiency increases with the inc

Multiple mechanisms of minor moraine formation in the Schwarzensteinkees foreland, Austria

This paper presents a detailed sedimentologic data set of minor moraines (heights ≤2.0 m, widths ≤14 m, lengths ≤108 m) that formed beginning near the end of the Little Ice Age by Schwarzensteinkees, a valley glacier in Austria. Sorted sediment and stratified diamict dominate five exposures, and compact massive diamict exists in one exposure. This sediment is interpreted as proglacial outwash and

Gender Bias in Academia

Gender, being an identity contingency as coined by Claude M. Steele in his book Whistling Vivaldi, is not self-chosen, is virtually impossible to escape, and comes with expectations, prejudice and – most importantly – uneven pre-conditions for our choices in life. Gender inequality is a wide-spread problem, causing much harm on theindividual and societal levels, and the academic world is no exempt

A low-eccentricity migration pathway for a 13-h-period Earth analogue in a four-planet system

It is commonly accepted that exoplanets with orbital periods shorter than one day, also known as ultra-short-period (USP) planets, formed further out within their natal protoplanetary disks before migrating to their current-day orbits via dynamical interactions. One of the most accepted theories suggests a violent scenario involving high-eccentricity migration followed by tidal circularization. He

Assessment of sustainability aspects when making pre-renovation decisions

En betydande del av Europas byggnadsbestånd behöver renoveras. De vanligaste anledningarna till att man genomför renoveringar är akuta tekniska problem eller en byggnads eller dess komponenters utgående livslängd. Andra vanliga skäl för byggherrar att genomföra renoveringar i sitt byggnadsbestånd är höga kostnader för underhåll och drift samt ett högt energibehov. Dessutom har bygg- och fastighetsA considerable amount of Europe’s building stock needs to be renovated. The most common reasons for carrying out renovations are acute technical issues or the expiring life span of a building or its components. Other common reason for building owners to carry out renovations in their building stock are high costs for maintenance and operation, and a high energy demand. Furthermore, the constructio

Are cortical microvascular raspberries caused by cerebral hypoperfusion? An exploratory pathological study

Introduction: This retrospective study investigated a cortical microvascular formation, termed a ‘raspberry’ due to its appearance under a bright-field microscope. We examined whether there is support for the hypothesis that raspberry formation is an angiogenic process induced by cerebral hypoperfusion. Materials and Methods: Raspberries were manually quantified in haematoxylin and eosin-stained c

Factors predicting recurrence in rectal cancer

Background: Rectal cancer treatment has improved through important incremental surgical and oncological developments over the past decades. Localized disease is highly treatable with multimodal surgical and oncological therapy. Prognosis is dependent on several factors with tumour stage at diagnosis being the most important. Furthermore, curative treatment is highly dependent on radical surgical r

Protection from herbivores varies among ant genera for the myrmecophilic plant Leea aculeata in Malaysian Borneo

Some plants use food bodies to attract ants that then provide protection from herbivory. A brief report from 1898 describes the myrmecophilic plant Leea aculeata Bl. as bearing food bodies on its young shoots, which accumulate when they are not harvested by ants. However, ant efficacy in deterring herbivores and consequences for herbivory rates remain unknown. Here we investigate (1) which ant tax

Maximum Radiation Efficiency of Implanted Antennas Employing a Novel Hybrid Method

A hybrid combining T-matrix method and electric field integral equation is used to formulate fundamental bounds on radiation efficiency of an implanted antenna. Resulting quadratic optimization problem is solved using a dual formulation. The results present the versatility of the described computational scheme and show the optimal current densities that are the least impaired by dissipation in the