Cell physiology and cellular responses to external stimuli are partly controlled through protein binding, localization, and expression level. Thus, quantification of these processes is pivotal in understanding cellular biology and disease pathophysiology. However, it can be methodologically challenging. Immunofluorescence is a powerful technique, yet quantification by this method can be hampered b

Lignin is the most abundant aromatic biopolymer on earth and has the potential to play an important role in the transition from an oil-based refinery to a biorefinery-based industry. The isolation of lignin from the biomass can be achieved by several different technical processes and isolated lignins are referred to as technical lignins in literature. During the last decades, the conversion of tec

Culturally oriented consumer research has predominantly been framed by two ideal types of reflexivity, which we characterize as existential and critical reflexiv-ity. Drawing from our research on divorced women who have been displaced from their domestically oriented, middle-class lifestyles, we develop an alternative con-ceptualization-reactive reflexivity-that highlights a different relationship

Huntington’s disease (HD) is a progressive, multifaceted neurodegenerative disease associated with weight loss and gut problems. Under healthy conditions, tight junction (TJ) proteins maintain the intestinal barrier integrity preventing bacterial translocation from the intestinal lumen to the systemic circulation. Reduction of TJs expression in Parkinson’s disease patients has been linked with inc

Tumor cell behaviors associated with aggressive tumor growth such as proliferation, therapeutic resistance, and stem cell characteristics are regulated in part by soluble factors derived from the tumor microenvironment. Tumor-associated astrocytes represent a major component of the glioma tumor microenvironment, and astrocytes have an active role in maintenance of normal neural stem cells in the s

This paper examines astrology, a concept that is considered unscientific by broad segments of the population in the western world. Despite this, astrology remains for some an important source for advice regarding choices in a range of different matters, including career and relationships. The continuing popularity of astrology may at least partly be linked to an insufficient body of empirical rese

Background: People with severe mental illness (SMI) living in supported housing (SH) struggle in everyday life and we currently lack a comprehensive body of knowledge concerning how the residents experience their day. This paper aimed to gain knowledge about how people with SMI describe a day in SH in Sweden, in particular the activities they most frequently engage in and how they experience what

Background: The receptors for advanced glycation end products (RAGE) are increased in atherosclerotic plaques. Soluble (s)RAGE decreases, whereas the extracellular newly identified receptor for advanced glycation end products (EN-RAGE) increases inflammatory responses mediated by RAGE. The aims were to explore whether sRAGE, EN-RAGE and the EN-RAGE/sRAGE ratio, were associated with the use of lipi

In this paper, pure paraffin was mixed with CuO (high thermal conductivity) and Span-80 (as a dispersant). The CuO/paraffin nanocomposite phase-change materials (PCMs) were synthesized with mass fractions of 0.3%, 0.6%, and 1.2%, by a two-step method. Heat-transfer characteristics of the heat-pipe-PCMs module and effects of fan power and heating power on the performance of the cooling module in a

This study aimed to compare patient outcomes following case method learning and traditional lectures as methods for continuing medical education (CME) about chronic obstructive pulmonary disease (COPD) for general practitioners (GPs) in Sweden. In a pragmatic cluster randomized controlled trial, COPD patients (n = 425; case method group n = 209, traditional lectures group n = 216) from 24 primary

Background: This study is designed to provide detailed knowledge on cognitive impairment after out-of-hospital cardiac arrest (OHCA) and its relation to associated factors, and to validate the neurocognitive screening of the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2-trial), assessing effectiveness of targeted temperature management after OHC