Similar to other malignancies, urothelial carcinoma (UC) is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is less clear. We applied tiling resolution array CGH to 146 cases of UC and identified a number of re

Popular Abstract in Swedish Ofrivilligt urinläckage, urininkontinens, omfattar mer än 50 miljoner människor i världen, varav cirka 500 000 i Sverige. Av dessa beräknas 2/3 vara kvinnor. Ofrivilligt urinläckage är ett medicinskt och socialt handikapp för den drabbade, operation och hjälpmedel förorsakar samhället stora kostnader. Risken för urininkontinens ökar med stigande ålder. I svenska studierAbstract Pelvic floor disorders (PFD) represent a major public health issue worldwide. Aims of this work Study I: to investigate associations between preoperative resting urethral parameters (MUCP, FL and CA) and objective outcome of laparoscopic colposuspension and, if possible, to identify cutoff values useful in clinical practice. Study II: to investigate a group of perimenopausal women reporti

Popular Abstract in Swedish Det religiösa landskapet i Europa genomsyras av rituell kreativitet - inom teater, psykoterapi och religiösa samfund laborerar individer och grupper med rituella former under mer eller mindre obundna förutsättningar. En stor del av det rituella nyskapandet återfinns emellertid utanför de etablerade religiösa institutionerna och traditionens ortopraxi. Här ses ritualer oRitual creativity may seem like a contradiction in terms, yet the religious landscape in contemporary Euro-America is permeate with experimentation of ritual forms, different modalities of action, imagination and play as routes to authenticity. The present study examines different settings in Europe involved in such ritual creativity, which would commonly be classified as postmodern spirituality,

Regulation of mRNAs is one way to control protein levels and thereby important cellular processes such as growth, invasion and apoptosis. G3BPs constitute a family of mRNA-binding proteins, shown to be overexpressed in several cancer types, including breast, colon and pancreas cancer. G3BP has been reported to both stabilize and induce degradation of specific mRNAs.

Results from the excursion of the 20th biennial symposium in Vadstena 11–15 August 2013 are presented. Eight localities in and around Vadstena were visited. Forty-three species are reported as new to the province Östergötland [Ostrogothia], three of which are new to the Nordic countries: Lecanora compallens, Polycoccum kerneri and Tremella caloplacae, five are new to Sweden: Cornutispora ciliata,

Recent theoretical analysis suggests that a reduction in the cost of exporting increases the degree of assortative matching between workers and firms in export-oriented industries. Changes that reduce the cost of imports have an ambiguous impact on matching. We combine detailed Swedish matched worker-firm data from 1995 – 2005 with tariff data to test these hypotheses. The data cover 94 sectors su

Dose conversion coefficients relating the kerma free-in-air to effective dose have been studied. In order to do so a sampling scheme encompassing all the risk organs and tissues was developed for the Alderson RANDO phantom. Preliminary results are shown for some specific organs irradiated with a point source in the laboratory.

The formation of various aluminides and intermetallic compounds in the Al-Ni-Ti ternary system offers great potential for a wide variety of applications. In the present work, reactions occurring during the heating of compacted ternary Al-Ni-Ti elemental powder mixtures were studied using differential scanning calorimetry (DSC). The effect of composition on the reaction behavior was studied by vary

Aims: To study mortality rates among patients with diabetes and concomitant atrial fibrillation (AF), prescribed different cardiovascular drugs in primary health care. Methods: Study population consisted of men (n = 1319) and women (n = 1094) aged = >= 45 years from a database including 75 primary care centres in Sweden. Cox regression analysis, with hazard ratios (HRs), 95% confidence interval (9

BACKGROUND: Differences in the estrogen receptor (ER) status of tumors may explain ambiguities in epidemiologic studies between the blood concentrations of enterolactone and breast cancer. To our knowledge, the association between enterolactone and ERbeta-defined breast cancer has previously not been examined.METHODS: A nested case-control study within the Malmö Diet and Cancer cohort used 366 cas

Phage display technology has emerged as a leading approach to select proteins with improved properties for many different types of applications. The selection typically selects not only for improved binding properties but also for other factors such as efficiency of protein production and folding in Escherichia coli, the host in which the proteins and the phage are produced. Furthermore, the selec

Aims To compare change in dietary intake, with an emphasis on food groups and food intake behaviour, over time across treatment arms in a diabetes prevention trial and to assess the differences in dietary intake among demographic groups within treatment arms. Methods Data are from the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. Participants were randomized to a life

The streaming instability is a promising mechanism to overcome the barriers in direct dust growth and lead to the formation of planetesimals. Most previous studies of the streaming instability, however, were focused on a local region of a protoplanetary disk with a limited simulation domain such that only one filamentary concentration of solids has been observed. The characteristic separation betw

Abstract in Undetermined In the global market of air transport, the integration of products and services is seen as being necessary for the long-term success of engine manufacturers. A flow of in-service information to designers is crucial for minimising in-service issues. A literature review showed that there are no studies that have proposed or developed methods or tools to support designers in

It has been widely observed that there exists a fundamental tradeoff between the minimum (Hamming) distance properties and the iterative decoding convergence behavior of turbo-like codes. While capacity-achieving code ensembles typically are asymptotically bad in the sense that their minimum distance does not grow linearly with block length, and they therefore exhibit an error floor at moderate-to

Recent work on geometric vision problems has exploited convexity properties in order to obtain globally optimal solutions. In this paper we give an overview of these developments and show the tight connections between different types of convexity and optimality conditions for a large class of multiview geometry problems. We also show how the convexity properties are closely linked to different typ

We report on a setup for the investigation of proton acceleration in the regime of target normal sheath acceleration. The main interest here is to focus on stable laser beam parameters as well as a reliable target setup and diagnostics in order to do extensive and systematic studies on the acceleration mechanism. A motorized target alignment system in combination with large target mounts allows fo

The aim of this study is to develop better understanding on organized self-help housing as an enabling shelter and development strategy to overcome poverty and build more resilient communities. The study addresses organized self-help housing from three different perspectives: a) current practice in developing countries; b) institutional approaches; and, c) the organized self-help housing process.