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The thermophilic bacterium Rhodothermus marinus produces several thermostable glycoside hydrolases. The studies presented in this thesis were performed on two enzymes, belonging to glycoside hydrolase families 10 and 12, produced by this microorganism. The family 10 xylanase, Xyn10A, is modular in architecture consisting of five domains or modules. The two isolated N-terminal modules were p

Purpose: To identify and evaluate possible causes of poor patient-reported visual function after cataract surgery. Methods: We obtained retrospective data from the Swedish National Cataract Register on patient self-assessed visual function before and after cataract surgery based on the Catquest-9SF questionnaire. We identified patients who self-reported similar or more difficulties postoperatively

Objectives: Patients with antineutrophil cytoplasmatic antibodies-associated vasculitides (AAV) exhibit higher mortality than the general population. In the current study, we assessed whether cluster affiliation based on clinical presentation might predict mortality. Methods: With case record review, the outcomes for a population-based cohort of patients diagnosed with AAV in southern Sweden (catc

Human brown fat tumors (hibernomas) display concomitant loss of the tumor suppressor genes MEN1 and AIP. In the present study, we hypothesized that the brown fat phenotype is attributed to these mutations. Accordingly, we demonstrate that silencing of AIP in human brown preadipocytic and white fat cell lines results in the induction of the brown fat marker UCP1. In human adipocytic tumors, loss of

Introduction: Central venous access devices facilitate home treatment in boys with haemophilia. These are usually fully implanted lines, referred to as ports. Caregivers are taught to manage the port using sterile techniques and maintaining patency by flushing with saline or heparin solution. National and international guidelines for the home care of ports are lacking. Aim: To evaluate if infectio

Background: The Autism Diagnostic Interview-Revised (ADI-R) is considered a first choice assessment tool in autism spectrum disorder. Nevertheless, despite its wide use in psychiatric practice and recommendations by various clinical guidelines, its interrater reliability has predominantly been confirmed in research settings by specially trained, research reliability interviewers. The reliability o

Late medieval towns have often been neglected within the urban archaeological paradigm. This article tries to discuss the medieval urbanization from the perspective of small late medieval towns in relation to other types of central places by using a regional perspective. The towns of Vimmerby and Eksjö, and the central places of Värnamo and Vetlanda in Småland are used as examples. In this region,

Denna bok är avsedd att vara en vägledning och fördjupning till utställningen Skatter i Skåneland. Boken innehåller dels en kronologisk översikt över såväl det historiska som det numismatiska skeendet i Skåneland under den tid när man där präglade mynt, och dels spännande historier kring de myntfynd som visas i utställningen. Tanken är att boken skall vara besökaren till nytta i utställningen men

This book is intended as a guide to the exhibition "Treasures in Skåneland”, providing further information. The book contains a chronological survey of general and numismatic history in Skåneland during the time when coins were minted here, as well as descriptions of the coin finds on show in the exhibition. The idea is that the book will be of use to visitors in the exhibition, while also making

Solid tumors in childhood are extremely rare entities, which are usually treated in specialized centers. Diagnosis and therapy are carried out according to a joint European protocol, whereby the pathological evaluation and therapy are carried out according to international guidelines. For the correct diagnosis and/or therapy of most tumors, analysis of specific genetic changes is mandatory; theref

We present the suggested temperature control system of the future ESS phase-reference line. The poster describes modeling, simulation, choice of hardware components, control algorithm, and measurement results from a 4.5 meter prototype developed at the Department of Automatic Control at Lund University in close collaboration with the European Spallation Source (ESS). The measurement results indica

Background: Lung cancer is the leading cause of cancer death. Little is known about whether prediagnostic nutritional factors may affect survival. We examined the associations of prediagnostic calcium intake from foods and/or supplements with lung cancer survival. Methods: The present analysis included 23,882 incident, primary lung cancer patients from 12 prospective cohort studies. Dietary calciu