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Mean and variance of absorption time in a population genetics model: Comparison between Markov chain and diffusion process methods.

Den matematiska teorin för populationsgenetik utvecklades av Sewell Wright och Ronald Fisher under 1920-30 talet. Wright-Fishers modell för evolution beskriver hur frekvenser av gener i en generation kan beräknas från frekvenserna i den föregående generationen. Förändringar i frekvenserna, evolution, uppkommer på grund av mutationer och selektion, men även på grund av slumpen, så kallad drift. Så Finding the expected number of generations it takes before every individual in a population (of constant size) only has one type of gene at a particular locus of a chromosome, can be formulated as computing the mean absorption time in a Markov chain. However, the Markov chain approach is inappropriate when the population is large. This is commonly solved by approximating the Markov chain with a di

Evaluation of FIWARE’s Business API Ecosystem

The modern society is getting more and more digitalized and the concept Internet of Things is growing. The data being collected and digital services require a place to be accessed and sold, thus setting the demand for a new kind of marketplace; an online IoT focused marketplace. The large EU supported open source platform for Smart Solutions, FIWARE, has created such a marketplace, namely the Busi

Basal body temperature curves and fitting with periodic smoothing splines

Fertility tracking phone apps are widely used by women today, in order to both achieve or prevent conception. Due to the health risks of hormone based contraceptions, many women opt for non-invasive methods, such as fertility tracking. Most of the algorithms for tracking fertility use parameters such as the basal body temperature (BBT), cycle length and days of menstruation. The widely used "

Betydelsefulla faktorer för drogfrihet : de professionellas perspektiv

Title: Significant factors for drug freedom -the perspective of the professionals(translated title) The purpose of this study was to investigate how social workers in the addiction care experienced what factors might be important when it comes to leaving the abuse and achieving drug freedom. The study follows the qualitative method in which four social workers on a support housing for adult addic

Utmattningssyndrom bland socialarbetare: En kvalitativ studie av socialarbetarens hantering av utmattningssyndrom

During the recent years there have been an increase in sick leave due to mental health issues all over Europe. In Sweden it started to rise in the 90’s and have not stopped since then. Today mental health disorders are the most common reason for sick-leave in Sweden. This applies especially among people working within human services, including social workers. Social workers have a high risk for st

Implementation of an 8-bit Dynamic Fixed-Point Convolutional Neural Network for Human Sign Language Recognition on a Xilinx FPGA Board

The goal of this thesis work is to implement a convolutional neural network on an FPGA device with the capability of recognising human sign language. The set of gestures that the neural network can identify has been taken from the Swedish sign language, and it consists of the signs used for representing the letters of the Swedish alphabet (a.k.a. fingerspelling). The motivation driving this projec

OECD-riktlinjerna och korrigeringsreglerna - Riktlinjernas rättskällevärde i svensk och tysk intern rätt

Uppsatsen undersöker rättskällevärdet för OECD:s riktlinjer om internprissättning för multinationella företag och skattemyndigheter vid tolkning av de s.k. korrigeringsreglerna i svensk och tysk lagstiftning. Genom internprissättning (transfer pricing) avgörs priserna vid transaktioner av fysiska varor och immateriella värden samt utförande av tjänster internt mellan närstående företag i multinatiThis paper examines the legal value of the OECD Transfer Pricing Guidelines for Multinational Enterprises and Tax Administrations as a source of law for the legal systems of Sweden and Germany with regards to internal law regulations enforcing compliance to the arm´s length principle in transfer pricing. Transfer prices are the prices at which enterprises transfer physical goods and intangible pr

Remittances and Household Expenditure - a Field Study in Addis Ababa, Ethiopia.

This study uses primary survey data to analyze the impact of international remittances on household expenditure across four different districts in the capital city of Ethiopia, Addis Ababa. The impact was explored by testing whether the share of different expenditure categories varies across recipient and non-recipient households. OLS methods were used to assess the impact of international remitta

Raggen går! En musiketnologisk studie av raggarkulturen i Venjan

Den svenska raggarkulturen är en av våra absolut mest seglivade subkulturer. Från att ha varit en stadsburen, beryktad ungdomskultur på 50-talet till att idag blivit en symbol för landsbygden. Syftet med den här musiketnologiska studien är att undersöka musikens roll och funktion för raggarkulturen i byn Venjan i norra Dalarna. I teorikapitlet förklarar jag olika musiketnolgiskabegrepp och perspek”Raggare” is one of Swedens most long-lived subcultures. From a city based, notorious youth culture in the 50s to a symbol today associated with the countryside. The purpose with this essay is to study the musical part in raggarkulturen in the village of Venjan in northern Dalarna. In the theory chapter I explain different ethnomusicology perspective and terminology such as emic and etic, music as

Undersökning av ett alternativt Nobelcenter

Det finns några pågående projekt som provocerar fram väldigt många och starka åsikter men få har involverat så många kvalificerade och uttalanden som Nobelcenter som planerades att byggas på Blasieholmen i Stockholm. Jag vill därför utforska projektet, läsa in vad som utmärkte vinnaren, vad som nu bromsade det samt utforska hur ett alternativ hade sett ut som jobbar med kritiken men ändå är placerIn this thesis I’m investigating the project to build a Nobel centre in central Stockholm. By first studying the competition, the winner and the critique it faced I then want to explore what a Nobel centre that tries to meet both critique and program might look like. The focus of the thesis lies in the investigation and the learning by exploring, the result in the end should be regarded as how far

Medborgarskapets symboliska betydelse

The contrasting perspectives of citizenship, as either participating in the national community through a common language or common values, contra the juridical meaning of citizenship as an upholding of ones rights and obligations towards the state, has in the last years gained strong foothold in the Swedish debate. This has led to an incertitude in how to interpret the term, and has made communita

Dealing with Death: The Romanticising of Tuberculosis in Three Victorian Novels

The purpose of this essay is to investigate whether the characters of Charlotte Brontë’s and Elizabeth Gaskell’s novels Jane Eyre, North and South and Ruth romanticise tuberculosis, how the disease was romanticised, and what qualities the affected characters had to possess to die from the disease. Major and minor characters who contract the disease are scrutinised, as well as the characters surrou

Aspects of Control in Donna Tartt's The Secret History

In literature there is a great variety of detective novels and The Secret History is one that presents the whydunnit-plot pattern, as the murderers are exposed early on. Another extensive part of The Secret History is its connection to Greek tragedies and Dionysian influences. Therefore these are considered and part of the formulation of this paper. I aim to establish ‘control’ as a unifying theme

Se men inte röra - Före detta gymnasieelevers upplevelser av fysisk kontakt och relationen med deras sångpedagoger

Denna studie utforskar sånglektionens sociala klimat. Speciellt fokus läggs på den fysiska interaktionen mellan sångpedagog och elev. Bakgrunden till studien finns i spåren efter #metoo då bland annat ett par pedagoger från svenska musikhögskolor fick lämna sina tjänster efter anklagelser om sexuella trakasserier under lektionstid. Syftet är att studera hur sångpedagoger på svenska gymnasieskolor This essay explores the social climate of the singing lesson. Particular attention is given to the physical interaction between singing teacher and student. The motive for this line of enquiry lies in the traces of the #metoo-movement when, amongst others, a couple of teachers were forced to leave their positions at Swedish music colleges due to accusations of sexual harassment during lessons. The

On the divergence of the Rogers--Ramanujan continued fraction on the Salem points

På divergensen av Rogers-Ramanujans kedjebråk i Salem punkter. Rogers-Ramanujans kedjebråk konvergerar inuti enhetscirkeln och divergerar utanför den. Dess beteende på enhetscirkeln är subtil, det finns en uppräknelig tät mängd där det konvergerar, en uppräknelig tät mängd där det divergerar, och för den återstående överuppräkneliga mängden är frågan om konvergens mestadels olöst. Bowman-McLaughlThe Rogers-Ramanujan continued fraction converges inside the unit circle and diverges outside of it. Its behavior on the unit circle is subtle, there is a countable dense set where it converges, a countable dense set where it diverges, and for the remaining uncountable set the question of convergence is mostly unsolved. The Bowman-McLaughlin conjecture says that we have divergence almost everywher

Expression and purification of Alpha-1-microglobulin-bikunin-precursor in E. coli

Syntes av AMBP i E. coli Vår kropp gör en proteinprodukt som heter Alfa-1-Mikroglobulin-Bikunin-Prekursor (AMBP) som sedan klyvs och blir två aktiva proteiner innan de lämnar cellen. Det ena proteinet kallas Alfa-1-Mikroglobulin (A1M) och det andra kallas bikunin. Dessa två proteiner kan inte syntetiseras separat, utan kommer alltid som ett paket. Dessa två proteiner har heller ingen fysiologisk

En moralisk erkännandepolitik? - En idéanalys om svensk moralsyn i erkännandet av Angola, Kosovo och Palestina

The significance of morality as an important variable for the analysis of international relations has been emphasized only in recent times. Therefore, this approach has not yet in Swedish scientific studies been used to cover the many branches in the field of Sweden’s foreign policy. As such, moral beliefs in Swedish recognition politics of states, as one of these branches, remains a gap in the po

Functional characterization of genetic loci identified in a genome-wide association study of blood lipid levels

Blood lipid levels are linked to the development of many metabolic and cardiovascular disease phenotypes, such as coronary heart disease and diabetes mellitus. Acquiring an understanding of the genetic variation that regulates lipid levels is important to elucidate the underlying biological pathways. In the present study, we performed a functional characterization for 103 independent SNPs that re

Mer feminism i utrikespolitiken? - En jämförande analys av Sveriges utrikespolitik före och efter deklarationen av den feministiska utrikespolitiken

In 2014, Sweden became the first country to promote and implement what became known as a “feminist foreign policy”. The concept was entirely new and was heavily discussed and questioned by both media and the international society at the time. This study seeks to explain whether the declaration of a feminist foreign policy agenda has brought any difference in the government’s policies. Is the forei