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There is a great need to identify new and better prognostic and predictive biomarkers to stratify prostate cancer patients for optimal treatment. The aims of this study were to characterize the expression profile of pre-B cell leukemia homeobox (PBX) transcription factors in prostate cancer with an emphasis on investigating whether PBX3 harbours any prognostic value. The expression profile of PBX3
Recent studies indicate that patients experience pain after day surgery for a longer period than previously known. This requires verification. This was a prospective, descriptive correlational study. A convenience sample of 298 day surgery patients undergoing various surgical procedures was asked to report pain intensity and its interference with daily function 48 hours, seven days and three month
This article discusses the emergence of the episcopal see in Växjö. Contrary to previous research, which has been focused on written sources only, this article also discusses the archaeological record. The result implies that vivid connections between Scania, Denmark and southern Småland can be traced in the Late Iron Age and Early Middle Ages. This is shown by similarities in grave types, runic s
The performance of a dry sampler, with an impregnated denuder in series with a glass fibre filter, using di-n-butylamine (DBA) for airborne isocyanates (200ml min-1) is investigated and compared with an impinger flask with a glass fibre filter in series (1 l min-1). An exposure chamber containing 1,6-hexamethylene diisocyanate (HDI), isophorone diisocyanate (IPDI), and 2,4- and 2,6-toluene diisocy
Sonographers have a high risk of musculoskeletal disorders. This study explores the associations between working conditions and musculoskeletal pain based on the frequency and intensity of pain in the neck and upper extremities. A questionnaire was answered by 291 female sonographers. High prevalence of neck/shoulder pain was associated with eye complaints and headache related to work on the compu
A method is presented for the determination of aromatic amines in aqueous extracts of polyurethane (PUR) foam. The method is based on the extraction of PUR foam using aqueous acetic acid (0.1%, w/v) followed by determination of extracted aromatic amines using hydrophilic interaction liquid chromatography (HILIC) and tandem mass spectrometry (MS/MS) with positive electrospray ionisation. The inject
Aim: The purpose of this paper is to provide a broad-based overview of the current literature regarding patients' experiences of symptoms following day surgery. Background: The advent of new anaesthetic and anti-emetic agents, advanced surgical techniques and the need for reduced costs for inpatient hospital services, has resulted in about 70% of all surgical procedures being undertaken as day sur
A method for screening of triazine herbicides in surface and waste water is presented. The method is based on an enzyme flow immunoassay (EFIA) for the detection of the free fraction of a horse radish peroxidase (HRP)-labelled antigen (tracer). This was accomplished by trapping the bound tracer fraction in a Protein G column, allowing the residual free tracer fraction to pass and be detected spect
A new and improved Holocene tephra stratigraphy and tephrochronological framework for eastern and northern Iceland is presented. Investigations of a sediment sequence from Lake Lögurinn have revealed a comprehensive tephra record spanning the last 10.200 years. A total of 157 tephra layers have been identified, whereof 149 tephra layers have been correlated to its source volcanic system using geoc
Background Colic affects at least 10% of newborns and parents seek help. The aim of this study was to present why infants whose parents sought help for colic, where not included in two colic trials and to describe the use and perceived effect of simethicone and probiotics amongst those infants who were included. Method A quantitative, descriptive sub-study based on unpublished data collected in
This article reports a comprehensive review of the research conducted regarding occupational balance. A scoping study method was used to explore and describe current research about occupational balance and to identify research gaps. Twenty-two articles published between 2009 and 2014 met the inclusion criteria. The articles reported studies conducted in eight countries on four continents, but the
Semi-arid regions play an increasingly important role as a sink within the global carbon (C) cycle and is the main biome driving inter-annual variability in carbon dioxide (CO2) uptake by terrestrial ecosystems. This indicates the need for detailed studies of spatiotemporal variability in C cycling for semi-arid ecosystems. We have synthesized data on the land-atmosphere exchange of CO2 measured w
In this study the effect of the dispersed state of soy phosphatidylcholine on emulsification is investigated. The emulsifier is either dispersed in the aqueous phase (coarsely, as small vesicles, as large vesicles), or it is dispersed in the oil phase. Oil-in-water emulsions are prepared with the emulsifier present in the different dispersed states. High-pressure homogenization is used for the emu
Familial osteochondritis dissecans (FOCD) is an inherited skeletal defect characterized by the development of large cartilage lesions in multiple joints, short stature, and early onset of severe osteoarthritis. It is associated with a heterozygous mutation in the ACAN gene, resulting in a Val-Met replacement in the C-type lectin domain of aggrecan. To understand the cellular pathogenesis of this c
Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins with guanidine-HCl. However, an unextracted collagen-rich residual is left after extraction. In addition, the high abundance of anionic polysaccharide molecules extracted from cart
The determination of proteins utilising a polymer-based restricted access support material with ion exchange properties (IERAM) is outlined. Solid phase extraction coupled on-line with a microbore reversed phase HPLC system for the quantitation of small marker proteins is demonstrated. The cation-exchange restricted access packings were characterised with respect to their adsorption and desorption
The development of high-speed flow immunoassay techniques is described. The principles are based on heterogeneous flow immunoassay interactions. High sample throughput can be used for screening small analytes in a number of biological matrices originating from samples of water from environmentally polluted areas, or biological fluids such as urine and plasma. The immunochemical detection principle
Protein identification through peptide mass mapping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has become a standard technique, used in many laboratories around the world. The traditional methodology often includes long incubations (6-24 h) and extensive manual steps. In an effort to address this, an integrated microanalytical platform has been d
An integrated protein microcharacterization/identification platform has been developed. The system has been designed to allow a high flexibility in order to tackle challenging analytical problems. The platform comprises a cooled microautosampler, an integrated system for microcolumn HPLC, and a capillary reversed-phase column that is interfaced to matrix-assisted laser desorption ionization time-o
