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Cervical cancer is the second most common cancer in females. The treatment, based on clinical FIGO stage, carries a significant risk of side effects. FDG-PET enables non-invasive studies of glucose metabolism. Cancer cells show an increased glucose uptake and metabolism that can be visualised and further analysed. The aims of this thesis were to evaluate FDG-PET in the clinical management of cerv
Different models and statistical mechanical approximations for titrating polyelectrolytes are studied and the results compared with Monte Carlo simulations and experimental data. Three types of models have been used in the simulations: i) rigid structures and freely jointed chains with ii) rigid bonds and iii) flexible, harmonic bonds. Sampling is facilitated for the latter two by the use of pivot
This thesis presents the research performed within two different research groups using heavy-ion induced nuclear reactions. They offer the opportunity to investigate different properties of nuclear matter. The results are based on measurements using a variety of different experimental techniques. The PHENIX experiment measured the production of deuteron and anti-deuterons at mid-rapidity in gold-
The search for polymeric materials with new property profiles has stimulated a great interest into polymer blends and reactive processing. During recent years many new blends have reached the market. Although some of these are homogeneous mixtures of polymers, most commercial blends are composed of immiscible polymers, and contain two or more polymeric phases. The properties of such blends depend
The most central question in the strategic management literature is why some firms are more successful than others, often expressed as an aim to understand sources of competitive advantage. In this thesis, an empirical observation is made that a number of manufacturing plants belonging to the same firm show sustainable differences in financial success, and the question is why. The main theoretical
The aim of this study is to contribute to an increased understanding of the demands that the operation’s character places on management control. The study’s point of departure is the assumption that management control must be adapted to the operation’s character in order to be able to support strategy implementation and the achievement of objectives (contingency theory). The study deals with the d
The analysis of the recorded electrical activity of the heart during an exercise test is a valuable method for investigating a patient's circulatory and respiratory system. But the disturbances that occurr during a test often make it difficult to interpret the signal in order to detect changes evoked by the increased workload and related to for instance coronary artery diseases. Suppression of dis
The final step in aerobic respiratory pathways is catalyzed by terminal oxidases. Bacteria generally have two or more terminal oxidases. Aerobically grown Bacillus subtilis synthesize three terminal oxidases: one cytochrome c oxidase, cytochrome caa3 and two quinol oxidases, cytochrome aa3 and cytochrome bd. In addition, a fourth cytochrome of bd-type has been predicted from the genome sequence. C
With the discovery of antibiotics, several diseases that were previously lethal is today readily cured, or so we thought. Some degree of resistance to one or several antibiotics can be found among many strains of clinical important bacteria. The problem has been somewhat kept at bay for the last few decades by altering already existing antibiotics, and thereby prolonging their usage. It is clear t
Synthesis and characterization of new transition metal carbonyl clusters has been undertaken, and evaluation of the new clusters to act as catalysts/catalysts precursor in asymmetric reactions has been carried out. The catalytic hydrogenation of tiglic acid under relatively mild conditions, using diastereomeric clusters of the general formula [(µ-H)2Ru3(µ3-S)(CO)7(µ-1,2-L)] (L= chiral diphosphine
The development in society and school activities that have taken place during the past twenty years, form the background to the problem in this thesis. Liberal democratisation in the society as a whole and the global explosion of knowledge have made it necessary for teachers continuously to develop new knowledge. The over all aim of the thesis concerned the development of knowledge of variations
The studies presented in Papers I to IV illustrate the importance of soil moisture in soil solution chemistry and response of native plants to the changes induced by change in moisture regime. With the help of glasshouse experiments I tried to study the influence of different treatments of soil moisture conditions on the mineral uptake by native plants of calcareous soil. I also tried to find the
Complex I is the mitochondrial enzyme complex that oxidizes NADH produced in the citric acid cycle and reduces quinone in the membrane, coupled to proton pumping out of the mitochondrial matrix, creating a membrane potential. This process generates about 40% of the energy used by living organisms. High-resolution structures of complex I recently became available, but the molecular mechanism behind
The free volume in polymers is coupled to several important physical properties, such as density, viscosity and gas diffusivity. The physical properties of polymers close to a solid surface have been shown to be significantly perturbed as compared to their bulk state. The behavior of polymers close to surfaces comes into play within the field of polymer composites, where the properties of the inte
Dyes are commercially indispensable and the expanding industry offers a complete palette of colors. Azo dyes constitute the largest chemical class of synthetic dyes because of their versatility, low price, and ease of production. These dyes may, however, pose health risk to humans due to formation of mutagenic/carcinogenic aromatic amines upon reductive cleavage of their azo groups (-N=N-). Theref
Radio systems, along with the ever increasing processing power provided by computer technology, have altered many aspects of our society over the last century. Various gadgets and integrated electronics are found everywhere nowadays; many of these were science-fiction only a few decades ago. Most apparent is perhaps your ``smart phone'', possibly kept within arm's reach wherever you go, that prov
The aim of this thesis is to examine interaction between the business community and academia, and consider the Science Park as a brokering environment and actor. The bulk of park-oriented research, like park-related practice, is based on network theory and thinking. Taking such an approach, it is natural to study the intensity and nature of the interactions of the involved parties – in this case,
Jahai, a language belonging to the Aslian branch of the Mon-Khmer language family, is spoken by a group of about 1,000 hunter-gatherers in the montane rainforests of northern Peninsular Malaysia. Drawing on linguistic data collected in the field, the present dissertation is a study of the grammar of Jahai. The work begins with an introduction to Jahai and its speakers, and subsequent chapters char
In this thesis different aspects of gel free procedures for mass spectrometry based proteome analysis are addressed, with emphasis on labelling techniques. It is based on three original articles where the effects imposed onto peptides upon modification are investigated, and the development of a new type of labelling strategy is described. Chemical modification has been of great importance for the
