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Methods for ensuring that the intended volume receives the intended absorbed dose in radiotherapy have been investigated. In order to optimise radiation treatment of cancer, geometric variations in the treatment chain need to be controlled. Furthermore, hazards potentially leading to unintended irradiation need to be controlled. While the required methods for optimisation of irradiation are divers
Several optically active organometallic Phe-AAn-Phe peptidomimetics and macrocyclic Phe-(Phe)n peptides have been synthesized by either intra- or intermolecular peptide bond formation of the corresponding bis(amino acid) derivatives. The key bis(amino acid) derivatives were available from an improved multi-step synthetic route, utilising Horner-Wadswort-Emmons olefination of organometallic aldehyd
A considerable part of chemistry in nature and industry, takes place in an environment of other molecules. Reactions, transitions, interactions or other chemical processes are almost always modified by the environment. These modifications or environment effects depend ultimately on the interactions between the molecules, the so called intermolecular interactions. The special case of effects induce
Tröger’s base was synthesized for the first time in 1887. The molecule is rigid, C2-symmetric and has a 90° angle, forming a chiral hydrophobic pocket. In this thesis, the synthesis of new analogues of Tröger’s base is described. 2- and 3-halo-substituted anilines have for the first time been condensed to Tröger’s base analogues. It has also been shown that anilines without substituents in para-po
Bob Dylan (b. 1941) became known as an enfant terrible and a regenerator of rock lyrics already in the tumultuous 60´s. His constantly shifting roles as musician and songwriter, combined with his notable reserve, have led to the growth of a plethora of myths surrounding his person and work. His lyrics, accompanied by an increasingly original rock backing, based on folk music and rhythm & blues
One of the main trends in the polymer industry today is the increasing importance of polymer blends. Combining two or more immiscible polymers in a polymer blend often leads to multi-phase materials with desirable properties. The typical poor morphological stability and low interfacial adhesion in these blends can be eliminated by adding compatibilizing graft copolymers. Well-defined graft copoly
During the past twenty years, considerable efforts have been invested in fundamental research on the thermochemical conversion of alternative solid fuels and on its areas of application. Today, the attempt is being made to develop processes for upgrading those fuels to become easy accessible energy sources of high efficiency. The thesis concerns thermochemical means for utilizing biomass. Light i
Shusaku Endo (1923-1996) is a Roman Catholic, Japanese novelist. From 1950 to 1953, he studied French literature in Lyon, France. Returning from Lyon, Endo began his career as a novelist. His early works include: White Men, Yellow Men(1954), A Wonderful Fool(1959), The Women in the Bible(1960), Foreign Studies(1965), etc. The present study analyses his work from the perspective of the inculturati
This thesis seeks to explore critically the idea of corporate criminal responsibility. The criminal responsibility of corporations is constructed as a criminal responsibility of legal persons. As an expression of criminal policy, criminal responsibility of corporations is often understood as a response to harms and risks stemming from the economic and industrial sectors of society. The central the
In vitro generation of antibody fragments of desired specificity and affinity plays an important role since it permits the generation of reagents which may be valuable for diagnostic and therapeutic applications. Furthermore, the kinetic parameters for an antibody-antigen interaction, rather than the affinity, has shown to correlate with biological functions like virus neutralization. This points
Political Culture and Social Engagement. An ethnological study of everyday parliamentary life in Helsingborg. The goal of my thesis is to, by examining foundational features which support political culture, make visible prerequisites for political engagement. Using diverse everyday situations, the thesis describes how one “does” politics. I follow two committee chairpersons in the municipality of
This thesis investigates structure-acoustic systems by use of finite element analysis. The systems studied here are limited to those that consist of an enclosed acoustic fluid cavity, which is coupled to a flexible structure and/or a porous sound absorbing material domain. This type of analysis is applicable to a wide range of engineering problems, for example, studying the interior noise in a ve
The significance of physical capital is often mentioned in general terms in economic history literature. In this study the amount of physical capital is calculated and its significance for industrial growth is analysed for the period 1870-1930. The largest and most important part of this thesis consists of constructions of capital stocks for industry as a whole and on the branch level. These cons
This study is built around the following research question: "How do student nurses conceptions regarding their future profession change during their training in the three year nursing programme?" The study is longitudinal in character and consists of qualitative interviews conducted with eighteen students belonging to the same nursing class. The students were interviewed on four occasions during
Viruses have developed several strategies to evade the complement system, a part of the immune system. The fourth open reading frame of the human virus Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a type 1 transmembrane protein. This contains four complement control protein domains (CCP domains), and is thus structurally similar to human complement inhibitors. We named it KSHV complement
Road profiles are studied from a vehicle fatigue point of view. A wide range of roads have been measured: from smooth motorways to very rough gravel roads. It is observed that the road profiles consist of irregular sections, which makes the stationary Gaussian model unsuitable (Paper A). In Paper B, a method for automatic identification of such irregularities is presented. It is verified that the
This volume is a new edition with a parallel English translation of eight Greek stories related to Daniel of Sketis: 1) Abba Daniel from Sketis; 2) Abba Mark the Fool; 3) The blind man; 4AB) A holy and chaste young woman; 5) The woman who pretended to be a drunkard; 6) Eulogios the Stone-cutter; 7) Andronikos the Money-dealer and his wife Athanasia; 8) Anastasia Patrikia. The stories deal with se
Abstract Centering on notation is a characteristic of Western tonal music. The printed scores are expected to provide the necessary information on musical expression. In this study, strategically selected contemporary musicians’ ways of under-standing the printed scores are investigated. All participants are thoroughly familiar with musical practice in Western tonal tradition. The intention is to
