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Air pollution is increasingly discussed as a risk factor for dementia, but the biological mechanisms are not yet fully understood. Biological markers like telomere length are relevant to study with air pollution, as they are associated with aging and dementia. The study aimed to investigate the relationship between source-specific air pollution exposure and telomere length in a low-level air pollu

Because of increasing pressures on marine life and habitats, the overall health of the global ocean has over the latter years received attention internationally. It is therefore of relevance to analyse how the type of human-nature relationship towards the ocean is presented through what can be coined as Blue Growth. The aim of this research is to critically discuss what human-nature relationships

Vegetation on land is globally taking up about 30% of the CO2 that is emitted by human activities (oceans take up 30%, while 40% remains in the atmosphere). This ability to store carbon in the vegetation and in the soil is very important to mitigate the climate changes, but all land based ecosystems are not carbon sinks. Ecosystems that are losing carbon needs to be further investigated, so we can

Background: Childhood cancer predisposition (ChiCaP) syndromes are increasingly recognized as contributing factors to childhood cancer development. Yet, due to variable availability of germline testing, many children with ChiCaP might go undetected today. We report results from the nationwide and prospective ChiCaP study that investigated diagnostic yield and clinical impact of integrating germlin

In this study, a literature review was conducted to identify indicators that can be utilised to assess and visualise the potential of the geophysical environment to deliver geosystem services. The literature review identified 24 studies and 22 technical reports, resulting in a list of 75 geosystem services indicators for 23 geosystem services associated with the subsurface. Building upon these fin

Background: Guidelines recommend neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC). Current recommendations do not consider genomic profiles, although the Basal/Squamous (Ba/Sq) subtype is less likely to respond to NAC compared to Urothelial-like (Uro) and Genomically Unstable (GU) subtypes. The aim of this study is to perform cost-effectiveness a

Background: Real-World evidence on mesenchymal-epithelial transition exon 14 skipping mutations (METex14) in lung cancer remains limited. With an incidence of 3–4% across histological subtypes, METex14 is now an actionable target for MET inhibitors (METi) in advanced lung cancer, demonstrating response rates between 30–70%. Yet, its role in early stages and sensitivity to immune checkpoint inhibit