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Biodegradation of the Recalcitrant Endocrine Disruptor Nonylphenol

Currently, over 100 high-volume chemicals have been classified as endocrine disrupters. One of these is nonylphenol, which was used as the model compound in this study. This substance originates mainly from the degradation of non-ionic surfactants (nonylphenol ethoxylates) which are widely used in industrial and domestic applications. Hence, nonylphenol is widespread in the environment. Under anae

Place Attachment and Climate-Related Hazards in Small Remote Communities in the Nordic Countries

Global climate change is characterized by increasing and differentiated exposure to climate-related hazards such as floods, landslides, avalanches, storms, and wildfires (IPCC 2018, 2022). There is a significant volume of research on the effects of such events, and over the last decade, much of this research has been directed at where most lives and values can be saved by protective measures (e.g.

Renaissance of a CRM system – Successful re-implementation out of an after market perspective

Problem: Today Frigoscandia Equipment Europe, FSEE, is not sure how their CRM-system, MSMS, is used along with other solutions at the different regions throughout Europe. The company is interested in a usage evaluation describing by who and how the system is used. FSEE is also concerned about the users opinions of future development and improvements. Management is also concerned about how MSMS wou

Renewable diesel fuels and emission control strategies : Implications for occupational exposure, human health, and the environment

Combustion of fossil diesel is a major environmental problem for both the climate and human health. Renewable diesel fuels have been developed and introduced to the market to reduce the net CO2 emissions. Emission control strategies, such as aftertreatment systems, have been implemented to reduce the health hazardous particulate matter (PM) and nitrogen oxides (NOx) emissions. The overall aim of t

Automatic identification of poorly performing substations and meter devices : The future of district heating

The district heating sector in Sweden is today facing several challenges due to competition from other heating alternativesas well as decreasing heat demand in buildings. To increase its competitiveness, the district heating companieshave to find ways to keep their production costs at a more or less constant level. One way of doing this is to increasethe efficiency of the district heating systems.

Voicing on the borders of language

My research engages with the varieties of relationship between verbal and non-verbal forms of language and communication. I approach the issue through three people who live or work with non-verbal people on the autistic spectrum: Phoebe Caldwell, Fernand Deligny and Iris Johansson. Their practices bring singular perspectives to my core question: How can we (re)conceive and engage with non-verbal f

Human enteroviral infection impairs autophagy in clonal INS(832/13) cells and human pancreatic islet cells

Aim/hypothesis: Human enteroviral infections are suggested to be associated with type 1 diabetes. However, the mechanism by which enteroviruses can trigger disease remains unknown. The present study aims to investigate the impact of enterovirus on autophagy, a cellular process that regulates beta cell homeostasis, using the clonal beta cell line INS(832/13) and human islet cells as in vitro models

Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

Importance: There are limitations in current diagnostic testing approaches for Alzheimer disease (AD). Objective: To examine plasma tau phosphorylated at threonine 217 (P-tau217) as a diagnostic biomarker for AD. Design, Setting, and Participants: Three cross-sectional cohorts: an Arizona-based neuropathology cohort (cohort 1), including 34 participants with AD and 47 without AD (dates of enrollme

Geometrical controls on spectral induced polarization in time and frequency domain

What can we learn by transmitting electrical currents through electrodes in the ground? Geophysical methods can help us to locate the bedrock, valuable mineral ores, remains of ancient buildings and many other secrets hiding below the surface. However, it is not only the universal interest for the unknown that drives the geophysical research forward. Knowledge of, for example, fractured bedrock, c

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies : a genome-wide linkage and sequencing study

Background: Most patients with Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies do not carry mutations in known disease-causing genes. The aim of this study was to identify a novel gene implicated in the development of these disorders. Methods: Our study was done in three stages. First, we did genome-wide linkage analysis of an Italian family with dominantly inherit

What Encourages Academic Staff to Engage in Systematic, Sustained Change in Teaching Practices?

Representing an international, multi-institutional research team, the panel presents a theoretical framework for understanding what prompts academic staff/faculty to change towards sustained use of pedagogies that make a meaningful difference in student learning. The theory grows out of a synthesis of literature on: the role of leadership and resources in emerging changes to teaching practices (Gi

Macro- and microvascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclerosis and vascular dysfunction in diabetes.

Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. Previous work fro

Physiotherapy in primary care for working-age patients with early back and neck pain. Screening tools, interventions and outcomes.

Besvär från rörelseorganen, framför allt från rygg och nacke är en av de vanligaste anledningarna till sjukfrånvaro i västvärlden. Patienter med dessa besvär utgör en stor andel av de som söker primärvården där fysioterapi ofta är första linjens vård. Rygg och nacksmärta kan orsaka nedsatt funktion och aktivitetsförmåga vilket ofta innebär en betydande förlust av livskvaliteten samt ekonomiska konPatients with back and neck pain are frequently seen in primary care, where they are directed to physiotherapy as first-line treatment. The condition affects both the individual, by causing pain and disability, and society, because of high costs caused by work disability and health care consumption. Clinicians need tools to identify, at an early stage, patients at risk of poor outcome, in order to

Advances in time–domain induced polarisation tomography : Data acquisition, processing and modelling

Vad står vi på – hur tar man reda på det? Kanske man kan titta på en geologisk karta, borra ett hål eller gräva en grop? Det kan gå bra, men ibland finns det inte tillräckligt detaljerade kartor och att gräva upp allt man är intresserad av är ingen lysande idé. Tänk om man kunde forska fram en metod som gör att man kan se rakt igenom marken, som röntgenundersökningar på sjukhus! På sätt och vis kaWhat would you find below your feet – how do you find out? Perhaps you could look at a geological map, drill, or dig? That could work, but sometimes the maps are not detailed enough, and digging everywhere to find out is impractical. Imagine if you could develop a method that allows you to see straight through the ground, as x–rays through the body! To some extent, such methods already exist; you

Narrative and Emotion in Education : Reading Literature as an Exercise in Affective Expression

General AbstractTraditionally, affects do not belong in the academic world, are not seen as compatible with science,the domain of objectivity. We have few teaching hours at our disposal and a large mass of content toput into them. This is true for academic literature classes, too, despite the fact that the "affectiveturn” at the beginning of the 21st century, thanks to scholars like Patrick Colm H

Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries : an analysis from the Global Burden of Disease Study 2016

BACKGROUND: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016), we measured 37 of the 50 health-relate

Primary and Secondary Outcomes from a Double Randomized Clinical Preference Trial of two Panic-Focused Psychotherapies

I Sverige kommer ungefär 2-3 % av befolkningen någon gång att drabbas av paniksyndrom med eller utan agorafobi (PS/A), ett tillstånd som består av plötsliga, oväntade panikattacker som följs av ihållande rädsla för nya attacker och/eller betydande livsstilsförändringar. PS/A debuterar oftast i slutet av tonåren eller i tidig vuxenålder och ger om den förblir obehandlad ofta kroniska psykiska besvä

High versus low-added sugar consumption for the primary prevention of cardiovascular disease

Background: High intake of added sugar have been suggested to impact the risk for cardiovascular disease (CVD). Knowledge on the subject can contribute to preventing CVD. Objectives: To assess the effects of a high versus low-added sugar consumption for primary prevention of CVD in the general population. Search methods: We searched Cochrane Central Register of Controlled Trials (CENTRAL) in the C