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AIMS: Atrial fibrillation (AF) is a frequent co-morbidity in heart failure (HF) associated with increased mortality, but little is known about the mechanisms underlying AF onset in HF patients. We evaluated the association of cardiovascular and genetic risk factors with AF in HF patients. METHODS AND RESULTS: Individuals hospitalized for HF (n = 1040; 500 with AF) were identified from a large, pop

Background: Overweight and obesity during pregnancy raise the risk of gestational diabetes and birth complications. Lifestyle factors like physical activity may decrease these risks through beneficial effects on glucose homeostasis. Here we examined physical activity patterns and their relationships with measures of glucose homeostasis in late pregnancy compared to non-pregnant women. Methods: Nor

Purpose: We investigated the distribution of cannabinoid receptor subtypes 1 and 2 in the detrusor of different species and studied the effects of cannabinoid receptor 1 and 2 agonists on bladder function. Materials and Methods: Cannabinoid receptor 1 and 2 expression was studied with Western blot and immunohistochemistry in rat, monkey and human detrusors. Co-staining was done for markers of sens

This intermediate report presents some of the important findings of the research work carried out during the first three years of the CHRISGAS project. The report is aimed at a broad technical-oriented audience such as: engineers with a general interest in the state-of-the-art and new developments in the biomass-to automotive fuel sector, and/or to teachers/lecturers/students in technical subjects

Lactic acid exists as two optical isomers, D- and L-lactic acid. For the production of biodegradable poly-lactic acid an optically pure product is desirable, but a racemate of known and constant ratio can also be used. Lactic acid can be produced either synthetically or fermentatively. Fermentative production has some advantages: by choosing a lactic acid bacterium producing only one of the isomer

The research project "Exclusive metalworking in rural settings" was instigated in 2013 with funding from Berit Wallenbergs foundation. The projects objective is to survey sites housing remains of multimetal craftsmanship of the late Iron Age and medieval periods outside urban contexts. This article aims to contextualize preliminary results from the project by evaluating its chosen source material

The bio-economy has been put forward as a strategy to increase economic growth without this leading to increased emissions of greenhouse gases. A key concept behind the bio-economy is the increased use of biomass for applications such as the production of bio-based chemicals and materials but also an increased importance for biotechnology and biorefinery systems in the production of these products

This chapter provides a synthesis of three earlier published studies (Garmy et al. 2012a; Garmy et al. 2012b; Garmy et al. 2013) (survey I) as well as previously unpublished results from a survey conducted in 2013 among students aged 16 (survey II). Objective: The aim was to investigate the effects of sleep, television use and texting and computer habits on overweight, enjoyment of school and fee

The main ambition of companies is to deliver products (or services) to customers successfully in order to remain competitive. This requires an efficient and effective product development process, as well as cost reductions and higher service levels through improved logistics performance in the supply chain. Traditionally, these two areas, i.e. product development and logistics, have been treated s

Aims. The aims of this study were to: (1) compare older people care nursing staff's perceptions of their competence, work strain and work satisfaction in nursing homes and home-based care; and (2) to examine determinants of work satisfaction in both care settings. Background. The shift in older people care from hospitals to community-based facilities and home care has had implications for nursing

OBJECTIVE-Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired beta-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin processing pathway could provide new insights about T2D pathophysiology. RESEARCH DESIGN AND METHODS-We have conducted a meta-analysis of genome-wide as

Converging evidence indicates that women with pregnancy-associated breast cancer (PABC) have increased mortality compared to women with breast cancer not diagnosed near pregnancy (non-PABC). Our aim was to investigate if the stage distribution differs between PABC and non-PABC and if stage at diagnosis can explain the poorer prognosis observed among women with PABC. We identified 3,282 breast canc