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OBJECTIVE: Biomarkers predicting risk of type 1 diabetes (stage 3) among children with islet autoantibodies are greatly needed to prevent diabetic ketoacidosis and facilitate prevention therapies.RESEARCH DESIGN AND METHODS: Children in the prospective The Environmental Determinants of Diabetes in the Young (TEDDY) study (n = 707) with confirmed diabetes-associated autoantibodies (GAD antibody, IA

Background: Disperse dyes (DDs) are the most prevalent causes of textile-related allergic contact dermatitis and are used for colouring synthetic textile materials based on fibres such as polyester, acrylic, acetate and polyamide. Eight DDs are included in a textile dye mix (TDM) 6.6% petrolatum (pet.) in the European baseline patch test series. Objectives: The aim of this study was to patch test

Background: Dioxins and polychlorobiphenyls (PCBs) are persistent organic pollutants that have demonstrated endocrine disrupting properties. Several of these chemicals are carcinogenic and positive associations have been suggested with breast cancer risk. In general population, diet represents the main source of exposure. Methods: Associations between dietary intake of 17 dioxins and 35 PCBs and b

Introduction: Air pollution is associated with increased risk of cardiovascular disease, possibly through chronic systemic inflammation that promotes the progression of atherosclerosis and the risk of cardiovascular events. This study aimed to investigate the associations between air pollution and established biomarkers of inflammation and cardiovascular disease. Methods: The Cardiovascular Subcoh

Components of the extracellular matrix (ECM), when exposed to body fluids may promote local complement activation and inflammation. Pathologic complement activation at the glomerular basement membrane and at the Bruch’s membrane is implicated in renal and eye diseases, respectively. Binding of soluble complement inhibitors to the ECM, including factor H (FH), is important to prevent excessive comp

Archivists tackle a variety of problems in their daily work, among them are issues concerning privacy-based material. This work demands a good understanding of the laws which govern this practice, laws comprising the Freedom of the Press Act (tryckfrihetsförordningen SFS 1949:105), the Public Access and Security Act (offentlighets- och sekretsslagen SFS 2009:400), and the Archival Law (arkivlagen

Background: The relationship between growth differentiation factor 15 (GDF-15) and the development of chronic kidney disease (CKD) is still unclear. We sought to examine whether plasma GDF-15 was related to incident CKD and kidney function decline using a large prospective cohort study. Methods: 4318 participants of the Malmö Diet and Cancer Study-Cardiovascular Cohort were examined in 1991-1994.

Background: The impact of body mass index (BMI) on mortality varies with age and disease states. The aim of this research study was to analyse the associations between BMI categories and short- and long-term mortality in patients with or without diabetes seeking care at the emergency department (ED) with acute dyspnoea. Population and methods: Patients aged ≥18 years at ED during daytime on weekda

BackgroundAssessment and treatment of the acutely ill patient have improved by introducing systematic assessment and accelerated protocols for specific patient groups. Triage systems are widely used, but few studies have investigated the ability of the triage systems in predicting outcome in the unselected acute population. The aim of this study was to quantify the association between the main com

Introduction: Umbilical cord blood measurement is the gold standard of evaluating neonatal metabolic status at birth. Dual sampling of cord blood vessels is clinical routine, yet the long-term value of venoarterial differences(ΔpH) is undetermined. The objective was to investigate the association of ΔpH, to long-term mortality and morbidity up to 20 years.Material and methods: This was a retrospecIntroductionUmbilical cord blood measurement is the gold standard of evaluating neonatal metabolic status at birth. Dual sampling of cord blood vessels is clinical routine, yet the long-term value of venoarterial differences (ΔpH) is undetermined. The objective was to investigate the association of ΔpH, to long-term mortality and morbidity up to 20 years.Material and methodsThis was a retrospectiv

Background: The prevalence of mental health problems is increasing, placing growing pressure on mental healthservices to provide care that is meaningful, accessible, and supportive for those who require it. However, currentpractices often do not fully meet individuals’ needs for person-centred, recovery-oriented, and integrated care andsupport. As these care and support models are being introduced

Global water scarcity requires innovative treatment solutions. This presentation explores three membrane-based concepts advancing from idea to pilot scale: stormwater harvesting with micro-/ultrafiltration (MF/UF), direct membrane filtration (DMF) for wastewater treatment, and a hybrid forward osmosis (FO), membrane distillation (MD), and nanofiltration (NF) system for seawater desalination.The EU