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High-energy breakfast with low-energy dinner decreases overall daily hyperglycaemia in type 2 diabetic patients: a randomised clinical trial

Aims/hypothesis High-energy breakfast and reduced-energy dinner (Bdiet) significantly reduces postprandial glycaemia in obese non-diabetic individuals. Our objective was to test whether this meal schedule reduces postprandial hyperglycaemia (PPHG) in patients with type 2 diabetes by enhancing incretin and insulin levels when compared with high-energy dinner and reduced-energy breakfast (Ddiet). Me

A Common SCN5A Variant Is Associated with PR Interval and Atrial Fibrillation Among African Americans

rs7629265 and AF Risk ObjectiveWe examined the association of rs7626962 (S1103Y) or rs7629265, a variant in high linkage disequilibrium with S1103Y (r(2) = 0.87 - 1), with sudden cardiac death (SCD) and atrial fibrillation (AF) among African Americans. BackgroundThe SCN5A missense variant S1103Y has been associated with SCD among African Americans in small case-control studies, but larger populati

Genetic Determinants of Trabecular and Cortical Volumetric Bone Mineral Densities and Bone Microstructure

Most previous genetic epidemiology studies within the field of osteoporosis have focused on the genetics of the complex trait areal bone mineral density (aBMD), not being able to differentiate genetic determinants of cortical volumetric BMD (vBMD), trabecular vBMD, and bone microstructural traits. The objective of this study was to separately identify genetic determinants of these bone traits as a

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

Mitochondrial dysfunction has been observed in skeletal muscle of people with diabetes and insulin-resistant individuals. Furthermore, inherited mutations in mitochondrial DNA can cause a rare form of diabetes. However, it is unclear whether mitochondrial dysfunction is a primary cause of the common form of diabetes. To date, common genetic variants robustly associated with type 2 diabetes (T2D) a

The occurrence of noncoagulating milk and the association of bovine milk coagulation properties with genetic variants of the caseins in 3 Scandinavian dairy breeds

Substantial variation in milk coagulation properties has been observed among dairy cows. Consequently, raw milk from individual cows and breeds exhibits distinct coagulation capacities that potentially affect the technological properties and milk processing into cheese. This variation is largely influenced by protein composition, which is in turn affected by underlying genetic polymorphisms in the

FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals.

FTO is the strongest known genetic susceptibility locus for obesity. Experimental studies in animals suggest the potential roles of FTO in regulating food intake. The interactive relation among FTO variants, dietary intake and body mass index (BMI) is complex and results from previous often small-scale studies in humans are highly inconsistent. We performed large-scale analyses based on data from

Jämställdhet genom lag eller avtal?

Uppsatsen behandlar förhållandet mellan jämställdhetslagstiftningen och principen om arbetsmarknadsparternas självständighet, och förlängningen motsättningen mellan de båda styrsystemen politik och marknad. Över tid har jämställdhetslagstiftningens innehåll och omfattning skärpts i flera omgångar, vilket åtminstone principiellt sett har inskränkt parternas självständighet. Trots detta präglas lagsThis essay concerns the relation between sex equality legislation and the independence of the labour market organisations. The relation can also be recognised as the opposition between the two steering systems politics and markets. Over the years the sex equality legislation has been sharpened several times, which has led to a limitation of the organisations’ independence – at least in a principle

Among "other" Citizens: Denizens and Anti-citizens - a Study of Exclusion of Undocumented Migrants at three Authorities in Helsingborg Municipality

The aim of this paper is to expand the debate on undocumented migrants' social rights from a theoretical perspective emphasizing social and political practices of inclusion and exclusion. We examine how processes of exploitation and stigmatization contribute to a categorization and positioning of undocumented migrants as non-citizens. We explore this in a dialogue with three authorities workin

"Jag går på soc" En kvalitativ undersökning om försörjningsstödtagares uppfattning om hur samhället ser på dem

Abstract Author: Charlotte Edvinsson Title: I support myself on welfare-A qualitative study of social assistance recipients idea of how society perceive them Supervisor: Agneta Hedblom Assesor: Torbjörn Hjort The need of social assistance has increased dramatically during the 1990s. In large due to the unemployment. A large number of studies have been made which look into how the clients have ex

Våtrum - Krav och regler

Wet room - demands and rules This paper explains how the legislative system is built concerning wet rooms within the construction industry. Legislation is developed by all involved authorities. The state has created laws and regulations through parliament and government. These laws are used as a foundation for Boverket, who has produced BBR, which specifies the minimum requirements for the propert

On the Legal Frameworks and Substantive Standards Governing the Granting of Interim Measures in International Commercial Arbitration

Interimistiska säkerhetsåtgärder är en viktig komponent i internationella skiljeförfaranden. Emellertid är institutet förenat med en rad oklarheter. Ett sådant element är de regelverk som reglerar beviljandet av interimistiska säkerhetsåtgärder meddelade av skiljemän. Vilka förutsättningar som ska vara uppfyllda för att en skiljenämnd ska bevilja säkerhetsåtgärder är inte fastställt, och olika tilThe institute of interim measures is an integral component in international commercial arbitration. However, there are uncertainties in terms of the procedural aspects of these measures. One pertinent issue is the legal frameworks that govern the granting of arbitral interim measures. The matter of what substantive standards and requirements to apply on requests for interim measures is unresolved,

Företagshemligheter & konkurrensklausuler - en intresseavvägning

Då Sverige har gått från ett industrisamhälle till ett kunskapssamhälle, har även behovet av ett starkare skydd för näringsidkaren uppstått. Dagens kunskapssamhälle har medfört att kunskap och kompetens fått en allt viktigare betydelse i företagens verksamhet. Det har skett en förskjutning från kunskap bunden i realkapital och maskiner till kunskap bunden till personer och personal. De anställda f

En inledande miljöutredning, Sparbanken Öresund

This thesis consists of an initial environmental investigation of the Sparbanken Öresund. The Bank currently has an environmental policy and ambitions from 2011 but no one has been responsible for implementation of them. In addition, upon my review of the policy and ambition list I found that there were neither measurable objectives nor procedures for how those objectives will be met, thereby crea

Uncertainty and sensitivity analysis in soil strata model generation for ground settlement risk evaluation

Scientific summary: Ground settlement due to groundwater drainage during construction is important to be considered since ground settlement may cause severe building damages. The calculation of ground settlement contained several parameters with different magnitude of uncertainties. Thus a risk evaluation of ground settlement is necessary. The aim of this thesis was first to build a soil strata mo

"Jag hade ett fängelse i mitt hjärta" - analys av en livsberättelse av en före detta kriminell person.

“I had a prison in my heart” – an analysis of a life story of a former criminal. The purpose of this study was to investigate stories featured in an autobiography written by a former criminal, based on theories of social psychology and interactionism. More specifically the aim was to study the reasoning and motives in the stories regarding the person’s relationships with significant others during