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Background/Objectives: Undergoing intensive cancer treatment, such as allogeneic haematopoietic stem cell transplantation, challenges the entire life situation of patients and their family caregivers. A prerequisite for effective care is that interventions are tailored to the unique circumstances of each individual. The aim of this study was to examine the feasibility of a developed person-centred
Objectives: Patients with acute type A aortic dissection (ATAAD) presenting with cerebral malperfusion have significantly poorer postoperative outcomes, making the decision whether to perform acute surgery difficult. The aim of this study was to investigate types of neurological symptoms and radiological findings and their association with permanent neurological injury and mortality following ATAA
Context: Adhesion G protein-coupled receptor (GPCR)-G1 (ADGRG1) is the most abundant GPCR in human pancreatic islets, but its role in islet function is unclear. Objective: Investigate how ADGRG1 expression and activation by its ligand, collagen III, impacts β-cell function in normal and type 2 diabetic (T2D) islets. Design: Genes associated with the ADGRG1 in human islets was probed by RNA-sequenc
Vitamin A-derived retinoic acid (RA) signals are critical for the development of several organs, including the pancreas. However, the tissue-specific control of RA synthesis in organ and cell lineage development has only poorly been addressed in vivo. Here, we show that retinol dehydrogenase-10 (Rdh10), a key enzyme in embryonic RA production, has important functions in pancreas organogenesis and
The importance of sexual selection in population divergence is of much interest, mainly because it is thought to cause reproductive isolation and hence could lead to speciation. Sexually selected traits have been hypothesized to diverge faster between populations than other traits, presumably because of differences in the strength, mechanism or dynamics of selection. We investigated this by quanti
The aim was to investigate healthcare consumption in men and women aged 65 and above in the two years preceding decision about long-term municipal care at home or in special accommodation and to investigate determinants for healthcare consumption. The study comprised 362 people (aged 65 or over), all subject to a decision about municipal care and/or services during 2002-2003, drawn from the Swedis
This thesis considers the design of PID controllers, the extensions of these controllers to improve their performance, and the applications of these design methods to industrial processes. New tuning methods for PI and PID controllers have been presented. These methods uses a model of the process to be controlled, given as a transfer function. The methods captures essential requirements of a cont
ABSTRACT Background We explored the impact of anastomotic leakage (AL) on the oncological outcome after anterior resection (AR) for rectal cancer which is still controversial.. Local recurrence (LR) and overall recurrenc(OAR) and cancer-specific survival were analysed. Method Patients undergoing AR for rectal cancer with a registered AL between 1995 and 1997 and a control group were identified in
OBJECTIVES: To examine whether the decrease in IMT progression rate in the carotid bulb induced by metoprolol CR/XL treatment (25mg once daily) observed in the β-blocker Cholesterol-lowering Asymptomatic Plaque Study (BCAPS) was accompanied by an effect on carotid plaque echogenicity. METHODS: Gray scale median (GSM) in carotid plaques, used as a score of echogenicity, was measured at baseline and
The transformation from analogue to digital recording techniques has not only changed the ways of working for the studiotechnician, but affects the musician in the way he thinks about performance and sound, and therefore also his actual performance. The signal processing and the staging of the singing voice in the studio is both influenced by, and influences the estethics of popular song performa
Competitiveness of city regions has gained a more and more central position in regional development and regional planning within the last decades. A reason for this is that globalisation has caused pressure on industrial structures forcing firms to increase their competitiveness by more actively promoting innovation and knowledge creation. Access to knowledge has therefore become vital for most ty
Teaching design history to future designers poses great challenges to me as an academic in the design field. There is a constant need to further describe and analyze how design and its history continuously are being made. The role of the designer implies the crafting of artefacts or at least an ability to communicate the possibility of them being materialized. Design history has mainly focused on
As home care increases and care is moving from nursing homes and hospitals into people’s homes, there are problem areas that need to be addressed and solved in a better way than today. Nurses and other home care workers are exposed to serval risks when the patients’ home environment becomes their workplace. There are also serval risks for the patients when their homes are transferred into “small h
