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Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome

Genetic and epigenetic factors may predispose women to polycystic ovary syndrome (PCOS), a common heritable disorder of unclear etiology. Here we investigated differences in genome-wide gene expression and DNA methylation in adipose tissue from 64 women with PCOS and 30 controls. In total, 1720 unique genes were differentially expressed (Q < 0.05). Six out of twenty selected genes with largest exp

Influence of soil frost on the character and degradability of dissolved organic carbon in boreal forest soils

Recent studies suggest that increases in extent and duration of winter soil frost increases dissolved organic carbon (DOC) concentrations in boreal riparian soils and connected aquatic systems during the subsequent spring and summer. However, little is known about the impact of frost on DOC character and its degradability. We applied three experimental treatments to riparian soils in northern Swed

Does Collaboration Include or Exclude? Participatory Aspects of Collaboration between Welfare Agencies when Investigating Suspected Child Abuse

Varying degrees of collaboration and consultation in the area of child and family welfare in the public sector has grown rapidly since the 1980s, especially concerning children at risk. Collaboration is understood to provide a more holistic view of the individual's needs, lead to better care and treatment as well as increase knowledge in general. Collaboration in that sense constitute a flexible a

Framing the Problem: Knowledge Brokers in the Multiple Streams Approach

A lot of attention has been focused on the policy stream of the multiple streams framework (MSF). John Kingdon used the role of the policy entrepreneur to theorize what was going on when problems become political issues. In order to fully grasp this process we need to further theorize also the problem stream. What is going on in the problem stream is defining the conditions for coupling done by po

Past and Present Roles of Packages in Logistics and towards the Future

Throughout history packages are used to contain, store and transport goods and products. In early days it was a matter of gathering and storing locally, whereas in today’s global enterprises packaging is an important issue in the operational management in networks of functions and/or divisions, often separated geographically around the world. Packaging has become a part of the process of efficient

Being with others: The commodification of relationships in tourism

The myriad of interpersonal relationships in tourism, between tourists, between tourists and locals, and between tourists and the service providers, are essential, generic components of the tourist experience. However, interpersonal relationships are emerging as a commercial value in the tourism industry as well, expressed for example in rural commercial home type of businesses, and in wellness-or

Drug prescription attitudes and behaviour of general practitioners. Effects of a problem-oriented educational programme

A producer-independent, problem-oriented, group-education programme with 2-day meetings on drug treatment in primary health care (PHC) was developed and evaluated. Initially, it was tested on a selected group of general practitioners (district physicians), using a non-exposed group as control. A comprehensive questionnaire was used to test changes in attitudes. There was a significant change in at

Lost Worlds? : Heritage in a Cultural Economy

Discussions of the cultural economy often focus upon the movement of such things as signs, media images, fashion and their entanglement in economic processes, but less attention has been paid to the concrete ways in which cultural heritage is affected by the processes and conditions of commoditization. This paper focuses upon how two museums of Scandinavian heritage struggle with very different cu

French as cL2, 2L1 and L1 in pre-school children

Compared to monolingual first language acquisition (L1) and adult second language acquisition (aL2), relatively little research has been done on child second language acquisition (cL2). This is an unsatisfactory situation from both a practical and a theoretical point of view. The present study concerns cL2 acquisition of French and poses the question whether cL2 acquisition bears closer resemblanc

Stochastic Modeling and Operational Optimization in District Heating Systems

Operation of a district heating system is accomplished via a sequence of decisions by the operators controlling the system. These decisions are based on expectations of conditions in the system that are not known at decision time. The operators could be helped by a decision support system that computes predictions of future system variables and suggests appropriate control actions given the availa