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Bus Rapid Transit (BRT) has predominantly been implemented in major urban areas worldwide, but interest is growing in its application within small and medium-sized cities. In these contexts, enhanced bus-based public transport is often essential for promoting more sustainable transport systems. However, limited research has explored how BRT can be adapted to smaller cities, particularly in Europe,
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Insulin resistance (IR) contributes to atherogenic dyslipidemia and elevated ASCVD risk. Apolipoprotein A1 (ApoA1)-associated lipoproteins have diverse anti-atherogenic functions, but it is unclear whether IR drives adverse changes in their proteomic composition. We hypothesized that IR is associated with an atherogenic ApoA1 proteome and that insulin-sensitizing interventions would improve its co
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Purpose: Direct laryngoscopy (DL) is the standard technique for endotracheal intubation. Video-assisted laryngoscopy (VL) has emerged as an alternative, particularly for difficult airway management. Nevertheless, DL and VL have not been systematically compared for simulation-based endotracheal intubation by inexperienced operators. Method: A prospective, randomized cross-over study was carried out
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Aims: This study compares the associations of Life's Simple 7 (LS7) and Life's Essential 8 (LE8) with all-cause and cardiovascular mortality in cardiovascular-kidney-metabolic (CKM) syndrome populations. Methods: This cohort study analyzed 11,487 participants aged ≥20 years with CKM syndrome from NHANES 2005–2018. Participants were categorized into non-advanced (stages 0–2) and advanced (stages 3–
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The technical development, involving digitalization, artificial intelligence, automation, and machine learning, can challenge the current tax system and consequently the means to finance public sector activities in several ways. If technology replaces labor, a tax base that is taxed relatively hard will be replaced by a tax base (capital) that generates less tax revenue, and consequently, less tot
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Timely diagnosis of type 1 diabetes (T1D), especially in high-risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases, having either those diseases or a family history of th
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Microglia exhibit targeted responses to different stimuli, including lipids, which can differ depending on the environmental conditions they encounter. These responses involve inflammatory mediators and are crucial for maintaining brain homeostasis. This study investigated whether inflammatory, metabolic, and phagocytic responses of microglia to the saturated fatty acid palmitate depend on extrace
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Bullying is increasingly understood as a group-based phenomenon in which bystanders play a critical role, yet little is known about how witnessing bullying affects bystanders’ self-esteem and academic motivation. The aim of this study was to explore adolescents’ perspectives on how witnessing bullying in school may be linked to their self-esteem and academic motivation. This qualitative study expl
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The downscaling of environmental responsibilities poses new challenges for regional governments, necessitating an evolution in their roles to manage environmental policy alongside traditional local development duties. This paper draws on the concept of the entrepreneurial state and on the idea of the ‘entrepreneurial region’ to explore how local and regional governments implement bioeconomy polici
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Purpose: Surgical repair of parastomal hernias (PH) is challenging, mainly due to high recurrence rates. The Local Parastomal repair (LoPa) is a novel technique utilizing a retromuscular synthetic mesh with an outward-facing collar. This study describes the LoPa technique and evaluates its outcomes. Methods: This single-centre study retrospectively reviewed 39 consecutive patients who underwent Lo
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Wastewater-based surveillance (WBS) allows the analysis of pathogens, chemicals or other biomarkers in wastewater to derive unbiased epidemiological information at population scale. After re-gaining attention during the SARS-CoV-2 pandemic, the field holds promise as a surveillance and early warning system by tracking emerging pathogens with pandemic potential. Expanding the current toolbox of ana
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Introduction: Child abuse is a global public health problem. It poses a threat to both physical and psychosocial well-being, resulting in serious consequences for the child, the family, and society. Radiographers are in a unique position to identify children at risk. In clinical practice, they may observe unusual interactions between children and their caregivers during radiographic procedures or
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Epithelial-to-mesenchymal transition (EMT), driven by cues from the tumor microenvironment, is a critical initiator of metastatic progression. In breast cancer patients, elevated expression of cartilage oligomeric matrix protein (COMP) is associated with shorter survival and increased metastatic risk. Here, we investigated the role of COMP in regulating EMT in breast cancer. Breast cancer cells tr
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Walking is a primary mode of transport in urban Africa, yet it remains unsafe, challenging, and unpleasant. In contrast, several European countries have implemented systematic policies to promote walking through Safe System principles. This study compares pedestrian safety in three African countries (Tanzania, Ghana, Zambia), with three European countries with excellence in road safety and Safe Sy
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Denna forskningsrapport inom ramen för ett MSB uppdrag identifierar och kartlägger relevanta datamängder för att bedöma tvärsektoriella sårbarheter för samhällsviktiga verksamheter och kritiska infrastrukturer på nationell svensk nivå. Totalt identifierades 108 datamängder, varav 49 bedöms vara relevanta för analyser på nationell nivå, 54 på regional nivå och 37 på lokal nivå. Identifierad och sam
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Micropollutant removal is a key component of the revised Urban Wastewater Treatment Directive (UWWTD) and can be achieved with ozonation. During ozonation, the composition of the wastewater matrix and the targeted treatment level for individual micropollutants or groups of such compounds affect ozone consumption. In this work, it was hypothesized that nitrite scavenging, the point of dosing (befor
