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OBJECTIVE-Human blood glucose levels have likely evolved toward their current point of stability over hundreds of thousands of years. The robust population stability of this trait is called canalization. It has been represented by a hyperbolic function of two variables: insulin sensitivity and insulin response. Environmental changes due to global migration may have pushed some human subpopulations

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Background Patients who have suffered from tuberculosis are at risk of respiratory failure with hypercapnea from chest wall deformity and hypoxia from pulmonary sequelae. The combination of hypercapnea and hypoxia justifies both mechanical ventilation and oxygen therapy as treatment options. We aimed to study which treatment mode is associated with the best survival in patients with the combinatio

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The clover seed weevils Apion fulvipes Geoffroy, 1785 and Apion trifolii L., 1768 (Coleoptera: Apionidae) cause major losses to seed production of white clover (Trifolium repens L.) and red clover (Trifolium pratense L.), respectively. Clover is important as animal forage and an alternative to inorganic fertilizers. Because clover is mainly pollinated by bees, the use of insecticides in management

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Background: Identification and adequate management of individuals at risk for hereditary nonpolyposis colorectal cancer (HNPCC) is crucial since surveillance programmes reduce morbidity and mortality. We investigated knowledge about key features of HNPCC in at risk individuals and physicians in surgery, gynecology and oncology. Methods: Data were collected using a questionnaire which was answered

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When designing innovations for the silver age, it is not sufficient to discover old people’s needs only. In addition, one also has to discover old peoples’ new roles as consumers, citizens and innovators. Since this is a group that until recently has been given few opportunities to make their voices heard, there is a need for methods that identify their needs and demands. More importantly, we need

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Stylistic Fronting (SF) is a process that fronts various types of non-subjects to the preverbal position in subjectless clauses (“that gone have”, etc.). With the exception of Icelandic and to some extent Faroese, SF has disappeared from Scandinavian varieties. It is commonly assumed that even in Icelandic it is formal and old fashioned, indicating that it might be on its way out of this language

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The purpose of building classification systems is to provide the sector with agreed and standardised ter¬minology and semantics, e.g. in systems for technical specification, cost calculation, and exchange of information. There is a growing need to use classification systems in a BIM context. In inter¬¬national construction projects and international construction product trade there is a need both

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One of the most important goals on solar collector development is to increase the system’s annual performance without increasing overproduction. The studied collector is formed by a compound parabolic reflector which decreases the collector optical efficiency during the summer period. Hence, it is possible to increase the collector area and thus, the annual solar fraction, without increasing the o

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Whilst Building Information Modelling (BIM) promises significant improvements in construction quality and efficiency, current contractual models do not encourage its use; indeed actively inhibit the collaboration at its core. To help bring BIM into the mainstream, it is claimed we need to re-craft existing contractual relationships to facilitate collaborative decision making and to equitably alloc

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According to Silvan Tomkins’ (1963, 1965) Polarity Theory, all ideologies are polarized by a fundamental conflict between Humanism, which idealizes and glorifies humanity, and Normativism, which portrays human beings as inherently worthless and able to attain value only through achievement of external norms. Research has shown that Humanism and Normativism do indeed form two coherent and negativel

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The objective of this thesis is to develop a strategy for statistical/econometric inferences applicable to systemwise testing of econometric models. A common deficiency in many applied econometric studies is the absence of statistical diagnostic testing. A model is only as good as the assumptions being used, and if these assumptions are incorrect then the model can be as good as worthless. In the

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The thermal insulation of clothing is commonly determined by dry thermal manikins either made of plastic or metal. For the determination of evaporative resistance of clothing ensemble, there exist three types of manikin methods: pre-wetted underwear or “skin” covered on dry manikins, the manikin with regulated constant water supply to the “skin” surface and the sweating fabric manikin based on a w

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Yesterday’s sole hardware product is becoming more and more rare. Today, the original products are increasingly surrounded by value adding services, software or control systems, all bundled together to a “total offer”. Christopher (1998) states that it is the totality of the offer which delivers customer value, and that adding value through differentiation and/or service is a powerful means of ach

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The paper describes measurements performed in three district heating (DH) substations in semidetached houses. In all these houses more than 40 % of the domestic hot water (DHW) tappings turned out to be shorter than 10 s. The fraction of total energy used to heat this water varied between 2.4 % and 10.2 %, indicating a large influence of households' daily habits. For 60-78 % of tappings, the total

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Since year 2000 a number of national energy management systems (EnMS) standards and specifications have been developed. To support EnMS implementation in industry some governments have launched agreements centered around energy management practices. National experiences show that such policy programs can achieve significant energy efficiency improvements. Implementation of industrial EnMSs has gra