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Extracorporeal immunoadsorption

Antibodies are important protein structures in the immunological defence. Occasionally the regulation of the production of these antibodies fails and antibodies directed against self structures are produced in large scale. Antibody production can also complicate or make transfusions and transplantations impossible. Purified protein A from Staphylococcus aureus immobilised to beaded agarose can ads

Microfluidic biosensing systems based on enzymes, antibodies and cells

The rapid developments within the life science and biotechnology areas put up ever-new demands on more sophisticated techniques and methods for chemical and biological analysis to reach deeper insight into the events at molecular level. Miniaturisation of assays and systems on microchips is one way to increase throughput and advance through parallel analysis lines, multiplexing and integration. Th

Konsten att hylla en polyglott. Mångspråkighet och språkpatriotism i ljuset av ett brev.

"In what language would one polyglot praise another? Multilingualism and linguistic patriotism in the light of a letter and a poem from Magnus Gabriel Block to Sophia Elisabeth Brenner." In the late 17th and the early 18th centuries, there was a dialectic relation between the increasing national concern for the native language on one hand, and the international multilingual culture where Latin was

Information management in industrial housing design and manufacture

Industrialized production of building components, or entire houses, reduces activities at the construction site to the assembly of parts and has the potential to increase productivity and reduce the design effort invested in every project. However, in order to realize all of the potential efficiency gains that use of predefined components could deliver effective, interoperable information manageme

'Arzteführerschule Alt-Rehse'--the main educational centre for promotion of Nazi medicine ideology in Germany during 1935 - 1943.

In Nazi Germany 1933-1945 the medical profession played an important role, not only within the health sector but also for ideological purposes. Some physicians committed criminal acts during the war, for example in concentration camps, and where later put on trial at the Nuremberg Trials in 1946-1947, some of them also sentenced to death. What is little known outside Germany is the existence of a

Plus(s) at(t) i skandinaviska — en minimal matris.

The word plus(s) can function as a conjunction in Scandinavian, and as such coordinate for example embedded clauses introduced by the subjunction at(t). However, one can also find examples of clauses introduced by plus(s) at(t) although not preceded by another at(t)-clause. These constructions, which represent a relatively new development in Scandinavian, are semantically similar to coordinations

Moss-nitrogen input to boreal forest soils: Tracking N-15 in a field experiment

Cyanobacteria living epiphytically on mosses in pristine, unpolluted areas fix substantial amounts of atmospheric nitrogen (N) and therefore represent a primary source of N in N-limited boreal forests. However, the fate of this N is unclear, in particular, how the fixed N-2 enters the soil and becomes available to the ecosystem. In this study, we applied N-15-ammonium chloride (N-15-NH4Cl) onto ca

Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction

Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflam

Modelling of Climatic Thermal Actions in Hollow Concrete Box Cross-Sections

The temperature distribution in concrete structures varies as a result of fluctuations in solar radiation, air temperature, wind speed and long-wave radiation. Variations in temperature may cause longitudinal and transverse movements. If these movements are restrained, stresses and strains can be induced, which may contribute to cracking in the structure. To predict such thermal actions in a hollo

Quality of life in patients with cronical lower limb ischaemia: Before and after revascularisation.

The aim of this thesis was to assess quality of life in patients with varying degrees of lower limb ischaemia before and after revascularisation, to assess quality of life in relation to the degree of ischaemia and the respondents’ sense of coherence (SOC) and in comparison with a healthy control group, and to compare two different quality of life instruments regarding their usefulness as outcome

Can pay-for-performance to primary care providers stimulate appropriate use of antibiotics?

Resistance to antibiotics is a major threat to the effectiveness of modern health care. This study examines if pay-for-performance (P4P) to care providers stimulates the appropriate use of antibiotics; in particular, if P4P can induce a substitution away from broad-spectrum antibiotics, which contribute more to the development of resistance, to less resistance-driving types. In the context of Swed

Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects

Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. the hydrolysis of triglycerides to diglycerides, and the subsequent hydrolysis of diglycerides and monoglycerides. However, MGL is needed to assure comple

EGF-like modules in blood coagulation proteins : Ca²+ binding, module interactions, structure and dynamics as studied by NMR spectroscopy

Modules are independently folding protein domains defined on the gene level. The epidermal growth factor-like (EGF) modules are involved in protein-protein interactions and are found in numerous membrane proteins and extracellular proteins, including many proteins of the blood coagulation system. A subset of the EGF modules binds one Ca2+ with an affinity that is often influenced by the

Knowledge as a source of power in real estate organisations

Purpose: The purpose of the paper is to explore how knowledge contributes to value adding activities within real estate organisations. More specifically, the study aims to investigate; (1) how knowledge sharing activities are perceived in real estate organisations, (2) what motivates individuals to share knowledge and what incentives are used to support them, and (3) if employees in these organisa