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Smooth muscle is characterised by high tension economy, low shortening velocity and regulation mainly by myosin light chain (MLC) phosphorylation. The aim of this study was to investigate regulation of force and maximal shortening velocity (Vmax) in smooth muscle. In intact muscle, activated with depolarisation, inhibition of force and rise in intracellular [Ca2+] ([Ca2+]i) by 2,3-butanedione mono
An enhanced dual-layer wide area wireless sensor network (WSN) system was developed and applied in fresh food tracking application. The sensor nodes of WSN provide a set of useful measurements about the environmental conditions during the fresh food transportation. Since the 3-axis acceleration data in such application account for more than 99% out of all collected source data, we propose a novel
In a recently conducted interview study, some survivors of traffic victims rate their home as the most important place for remembrance, compared to both the accident site and the burial plot. The reason for this evaluation appears to be the place’s ability to bring about a positive presence of the deceased. Supported by photographs and personal objects, the home serves as a constant reminder, and
The Nordic countries have often been seen as “fore-runners” of energy efficiency in buildings – in both the implementation of policy instruments and the evaluation of effects. Since the 1970s, the Nordic countries have introduced a range of policy instruments for energy conservation in buildings. The choice of instruments and experiences, however differs between countries. The aim of this study is
Results from experimental studies, as well as clinical studies, are used to elucidate the effects of ambient pressure changes on cochlear hydrodynamics and function. The perilymph pressure changes and the pressure release effects of the cochlear aqueduct (CA) and Eustachian tube (ET) in cats exposed to hypobaric pressure are elucidated. The focus is on the emergence of the pressure gradients betwe
Vehicle-to-vehicle (VTV) communications are of interest for applications within traffic safety and congestion avoidance, but the development of suitable communications systems requires accurate models for the VTV propagation channel. This paper presents a new wideband MIMO (multipleinput- multiple-output) channel model for VTV channels based on extensive MIMO channel measurements performed at 5.2
Interleukin (IL)-1beta is one of the most pleiotropic and potent cytokines, produced predominantly by activated monocytes and macrophages. IL-1 plays an important role in normal immunoregulatory processes but also in pathophysiological inflammatory responses. In the present study, we developed a model for active IL-1beta secretion. A retroviral vector containing a cDNA construct encoding the matur
The aim of this study was to visualize design regulations of furniture by means of interactive multimedia technology based on cognitive theories and practical examples. Furthermore, the usage of the visualized regulations to support education, communication, learnability, relevance and attitudes was evaluated. The visualized regulations were the result of a design process involving experts and pot
Structured reflective writing during clinical placement has been shown to be valuable for students’ learning and for their personal and professional development. The aim of this study was to examine clinical supervisors’ experiences of midwifery students’ daily written reflections on their practice at birthing units. A qualitative study was performed, and data were analysed using content analysis.
The social network was evaluated by means of the self-rating scale 'Interview Schedule for Social Interaction' (ISSI) and semi-structured interviews in married patients with a DSM-III diagnosis of schizoaffective disorder (N = 17, partners, N = 16), married patients with diabetes (N = 10, partners, N = 10) and in married healthy individuals (N = 8, partners, N = 8). The two latter groups were comp
Forestry is raising concern about the outbreaks of European spruce bark beetle, Ips typographus, causing extensive damage to the spruce forest and timber values. Precise monitoring of these beetles is a necessary step towards preventing outbreaks. Current commercial monitoring methods are catch‐based and lack in both temporal and spatial resolution. In this work, light scattering from beetles is c
Adipose tissue plays a major role in regulating whole-body energy metabolism. While the biochemical processes regulating storage and release of excess energy are well known, the temporal organization of these events is much less defined. In this study, we have characterized the presence of small surface-associated lipid droplets, distinct from the central droplet, in primary human adipocytes. Base
The new estimates of the Maddison Project show that the p.p.p. GDP per capita ratio between Bolivia and Finland has changed from 0.68 ca. 1850 to 0.16 in 2015; similarly, that between Chile and Norway from 0.65 to 0.28. The aim of this article is to present a review of the literature and available quantitative evidence to understand how these extreme differences became possible between countries w
This paper examines the short-term effect between take-up of Social Assistance Benefit (SAB) and mental health. Using a panel dataset including rich yearly register data on e.g. income, income sources, unemployment and types of pharmaceutical consumption for over 140,000 Swedes 2006-2012, we quantify the importance of the psychosocial dimensions (e.g. shame and guilt) of the socioeconomic status –
Orthostatic hypertension, which appears to be mediated through excess neurohumoral activation while standing, is a common blood pressure trait among patients with and without arterial hypertension. However, lack of consensus regarding the definition of orthostatic hypertension makes it difficult to assess the true prevalence of this condition. Orthostatic hypertension appears to predict the risk f
