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The overall aim of the thesis was to investigate the effects of psychodynamically oriented psychotherapy and gain an increased understanding of the curative factors in psychotherapy by thorough examination of the therapeutic alliance and of client change. The core of the thesis is a naturalistic study of 22 short-term dynamic psychotherapies and a follow-up 6-12 months later. Individual outcome me
The pathophysiologic mechanisms in type 1 diabetes (T1DM) involve loss of islet β-cell secretory function caused by selective killing of these cells primarily by aggressive autoimmune responses involving both cellular and humoral immune pathways. Inflammatory cells heavily infiltrate pancreatic islets leading to insulitis where CD8+ T lymphocytes are thought to be responsible for selective and spec
A method for detection and genotyping of genital Chlamydia trachomatis infections based on omp1 gene amplification and sequencing was developed. DNA was extracted from urogenital or urine samples using a Chelex-based method, and an approximately 1,100-bp-long fragment from the omp1 gene was directly amplified and sequenced. Genotyping was performed by BLAST similarity search, and phylogenetic tree
According to the traditional view, the relation between morphology and syntax is the following: while morphology builds up word forms—typically by combining roots with other roots and with affixes, but also by applying other operations to them, syntax takes fully inflected words as input and combines them into phrases and sentences. The division of labour between morphology and syntax is thus perf
The Kidd (JK) blood group system is clinically important in transfusion medicine. Alloantibodies to antigens in this system may be produced following blood transfusion or during pregnancy and can result in serious haemolytic transfusion reactions and haemolytic disease of the newborn (HDN). JK antigens on erythrocytes are carried by glycoproteins with the capacity to transport urea through cell me
Purpose Human papillomavirus (HPV) has been linked to oropharyngeal carcinomas, but its role in laryngeal squamous cell carcinoma (LSCC) is not clear. A prospective multicenter study based on known tumor-cell percentage of fresh frozen carcinoma biopsies was established to determine the HPV prevalence. Moreover risk factors such as smoking, alcohol abuse, chronic laryngitis and gastroesophageal re
