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Governing interdisciplinary cooperation in Centers of Excellence

In the past years Centers of Excellence (CoE) has risen to prominence as a funding instrument in science. The idea is that by focusing resources, people and attention within a center environment, and over a substantial time span, excellence in science can be promoted. Similarly, interdisciplinarity is often seen as an enabling condition or even necessary for frontier research. This article builds

Housing in the RiverCity : Rethinking Place and Process

On the banks of the Göta River, the city of Gothenburg is undergoing a transformation that characterizes many urban waterfronts today, as shipping, fishing, and naval uses are replaced by a high demand for new housing. What is unique to Gothenburg is its vision of a RiverCity that is diverse, environmentally sound, and vibrant. It is imperative, however, to take stock of the successes and failures

Educational Assortative Mating and Household Division of Labor : A pan-European Perspective

Educational homogamy has been increasing for a long time in the Western world but there has been much more research on describing and explaining this trend than actually looking at its consequences. Economic theory predicts that educational heterogamy is related to division of labor in accordance with comparative advantages in household and market production, but there has been few tests of this h

DAVID : An open-source platform for real-time transformation of infra-segmental emotional cues in running speech

We present an open-source software platform that transforms emotional cues expressed by speech signals using audio effects like pitch shifting, inflection, vibrato, and filtering. The emotional transformations can be applied to any audio file, but can also run in real time, using live input from a microphone, with less than 20-ms latency. We anticipate that this tool will be useful for the study o

Genetic Risk Prediction of Atrial Fibrillation

BACKGROUND—: Atrial fibrillation (AF) has a substantial genetic basis. Identification of individuals at greatest AF risk could minimize the incidence of cardioembolic stroke. METHODS—: To determine whether genetic data can stratify risk for development of AF, we examined associations between AF genetic risk scores and incident AF in five prospective studies comprising 18,919 individuals of Europea

KOSHIK: A large-scale distributed computing framework for NLP

In this paper, we describe KOSHIK, an end-to-end framework to process the unstructured natural language content of multilingual documents. We used the Hadoop distributed computing infrastructure to build this framework as it enables KOSHIK to easily scale by adding inexpensive commodity hardware. We designed an annotation model that allows the processing algorithms to incrementally add layers of a

Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes

Aim: To define the genomic distribution and function of DNA methylation changes during human adipogenesis. Methods: We isolated adipocyte-derived stem cells from 13 individuals and analyzed genome-wide DNA methylation and gene expression in cultured adipocyte-derived stem cells and mature adipocytes. Results: We observed altered DNA methylation of 11,947 CpG sites and altered expression of 11,830

Entangled media histories : The value of Transnational and Transmedial Approaches in Media Historiography

The transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employThe transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employ

Glycogen metabolism in the glucose-sensing and supply-driven β-cell

Glycogen metabolism in β-cells may affect downstream metabolic pathways controlling insulin release. We examined glycogen metabolism in human islets and in the rodent-derived INS-1 832/13 β-cells and found them to express the same isoforms of key enzymes required for glycogen metabolism. Our findings indicate that glycogenesis is insulin-independent but influenced by extracellular glucose concentr