Search results

P>A recent genome wide association study of chronic lymphocytic leukaemia (CLL) provided evidence that common variation at 2q13 (rs17483466), 2q37.1 (rs13397985), 6p25.3 (rs872071), 11q24.1 (rs735665), 15q23 (rs7176508) and 19q13.32 (rs11083846) affects CLL risk. To verify and further explore the relationship between these variants and CLL risk we genotyped case-control datasets from Spain and Swe

Using a genome-wide screen of 9.6 million genetic variants achieved through 1000 Genomes Project imputation in 62,166 samples, we identify association to lipid traits in 93 loci, including 79 previously identified loci with new lead SNPs and 10 new loci, 15 loci with a low-frequency lead SNP and 10 loci with a missense lead SNP, and 2 loci with an accumulation of rare variants. In six loci, SNPs w

Objective: To compare telephone interview screening for child psychiatric/neuropsychiatric disorders using the inventory of Autism-Tics, Attention deficit/hyperactivity disorder (AD/HD) and other Comorbidities (A-TAC) with results from the Child Behavior Checklist (CBCL). Background: The A-TAC is a parent telephone interview focusing on autism spectrum disorders (ASDs) and co-existing problems, de

Alternative splicing (AS) is a fundamental mechanism for the regulation of gene expression. It affects more than 90% of human genes but its role in the regulation of pancreatic beta cells, the producers of insulin, remains unknown. Our recently published data indicated that the 'neuron-specific' Nova1 splicing factor is expressed in pancreatic beta cells. We have presently coupled specific knockdo

Creative functioning,as shown in the Creative Functioning Technique (CFT) of Smith and Carlsson, fits well with what one of us (Andersson)in his model of the mind refers to as dialectical construction, a mode of functioning associated with (pre)adolescence, with Freud's topographic model, and with the creativity principle. It is possible by use of two percept-genetic techniques, the Defense Mechan

How have the dramatic events of the Second World War been viewed in the Nordic countries? In Nordic Narratives of the Second World War, leading Nordic historians analyse post-war memory and historiography. They explore the relationship between scholarly and public understandings of the war. How have national interpretations been shaped by official security-policy doctrines? And in what way has the

The European Spallation Source (ESS) will be the world's most powerful spallation neutron source when it comes in operation at the end of this decade. The ESS linac will accelerate 50mA of protons to 2 GeV in 2.86 ms long pulses at a repetition rate of 14 Hz on a tungsten target for neutron spallation. The linac contains 26 superconducting spoke cavities, which are being developed by IPN Orsay, Fr