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Evaluation of inter-departmental variability of ejection fraction and cardiac volumes in myocardial perfusion scintigraphy using simulated data.

Myocardial perfusion scintigraphy (MPS) is a clinically useful noninvasive imaging modality for diagnosing patients with suspected coronary artery disease. By utilizing gated MPS, the end diastolic volume (EDV) and end systolic volume (ESV) can be measured and the ejection fraction (EF) calculated, which gives incremental prognostic value compared with assessment of perfusion only. The aim of this

Categorization and analysis of academic patents: Developing a framework to examine differences in technology, opportunity and commercializaton characteristics

There has been a significant rise in the number of patents originating from academic environments. However, current conceptualizations of academic patents provide a largely homogenous approach to define this entrepreneurial form of technology transfer. In this study we develop a novel categorization framework that identifies three subsets of academic patents which are conceptually distinct from ea

Derivative Usage, Risk Disclosure, and Firm Value

Risk disclosure is generally regarded as crucial in order for investors to make informed decisions in the resource allocation process. Our study is the first to empirically investigate the value-relevance of corporate risk disclosure. We focus on the disclosure of foreign exchange (FX) risk, which is an activity notorious for its lack of transparency. Our empirical analysis involves a FX risk disc

A reference panel of 64,976 haplotypes for genotype imputation

We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies, and it can help to discover and refine causal loci.

Democratic Innovations: Reinforcing or Changing Perceptions of Trust?

Declining trust in representative institutions is considered one of the most significant political problems of our time. It is often suggested that democratic innovations—or mechanisms which aim to increase and deepen citizen participation in the political decision-making process—can help reverse this trend. However, empirical research about actual effects of participation on trust is scarce, and

Firm Size Distribution and Employment Fluctuations : Theory and Evidence

We show that the firm-size distribution is an important determinant of the relationship between an industry's employment and output. A theoretical model predicts that changes in demand for an industry's output have larger effects on employment, resulting from adjustments at both the intensive and extensive margin, in industries characterised by a distribution that has a lower density of large firm

When and how does commuting to cities influence rural employment growth?

This paper estimates the influence that rural-to-urban commuting has on rural employment growth, and whether the strength and spatial reach of this effect depend on commuters' levels of education. A main finding is that rural-to-urban commuting has a robust positive impact on rural employment growth in services and retail. There is no significant difference in how far these effects reach into rura

Progesterone metabolite influence feeding behaviour.

Obesity is increasing worldwide and is associated with increased risk of developing metabolic diseases. One of the factors that have been demonstrated to influence the regulation of appetite and food intake is the different sex hormones, one of these being progesterone that in humans increase food intake (Hirschberg, 2012). In this issue of Acta Physiologica, Holmberg and colleagues present their

Reproductive factors and epithelial ovarian cancer survival in the EPIC cohort study.

Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025 invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included 521 330 total participants (ap

'Ei helvetes dame’ : on Scandinavian pseudopossessors

In Scandinavian, nominal phrases can contain constituents that look like possessors without having a possessor theta role. These constituents, which I call pseudopossessors, come in three types: swearword pseudopossessors, measure pseudopossessors, and characterising pseudopossessors. I argue in this paper that pseudopossessors are -s-marked constituents that are located in the adjectival field in