Paleolithic Diet, Abdominal Adiposity, and Systemic Low-grade Chronic Inflammation. Associations in Observational Studies and a Randomized Controlled Trial
Background: Systemic low-grade chronic inflammation (SLGCI), commonly assessed by biomarkers such as total leukocyte count, neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein (CRP), is associated with cardiometabolic disease, and both are associated with diet and abdominal adiposity. The Paleolithic diet may reduce SLGCI by reducing abdominal adiposity and through direct effects on the i
