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The effect of smoking on response and drug survival in rheumatoid arthritis patients treated with their first anti-TNF drug.

Objectives: Smoking has been associated with higher disease activity and poor response to anti-tumour necrosis factor (anti-TNF) therapy in patients with rheumatoid arthritis (RA). We wanted to study the effect of smoking on response to therapy, disease activity measures, and drug survival in RA patients starting their first anti-TNF drug. Methods: In 2005, RA patients in a voluntary rheumatology

High-quality annotations for deep learning enabled plaque analysis in SCAPIS cardiac computed tomography angiography

Background: Plaque analysis with coronary computed tomography angiography (CCTA) is a promising tool to identify high risk of future coronary events. The analysis process is time-consuming, and requires highly trained readers. Deep learning models have proved to excel at similar tasks, however, training these models requires large sets of expert-annotated training data. The aims of this study were

Strategic communication practices on local level in public sector organizations - Micro-strategies and other social innovations in the empowerment process of building civic relations and trust

Sweden has during the past decades experienced increasing challenges in suburban, segregated areas: the inhabitants have different cultural and socio-economic backgrounds but despite that, face similar problems. Many inhabitants lack relevant networks as well as other opportunities to become a part of the society. These inhabitants claim they don´t have the “keys” to understand their society and i

Övervakning av fåglarnas populationsutveckling: : Årsrapport för 2022

I denna rapport redovisas populationstrender för 224 svenska fågelarter för olika långa tidsperioder, samt korttidstrender för 12 arter av större däggdjur. Fåglarna har räknats höst, vinter, vår och sommar enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996)men täcker h

On User Involvement in Research on Ageing and Health

The aim of this thesis was to explore the perceptions of, prerequisites for and benefits of user involvement among older people, persons with functional impairments and other user groups important to the research area. By using an adapted conceptual tool to categorize the various user involvement studies comprising the thesis, the aim wasalso to reflect on the importance of study design for the ou

Establishing a City Scan Procedure for Sustainable Virtual Tourism, in order to Save Built Cultural Heritage Based on case studies in Dubrovnik, Pärnu and Helsingborg

This paper investigates whether a City Scan Procedure (CSP) can be developed into a value enhancing and economically acceptable solution to make cultural tourismsustainable. The purpose of developing CSP into an established method is both to relieve stressed tourist destinations with strong anti-tourist reactions via site relocations and that its revenues primarily accrues to the host country, thu

Study protocol for a phase 1, randomised, double-blind, placebo-controlled study to investigate the safety, tolerability and pharmacokinetics of ascending topical doses of TCP-25 applied to epidermal suction blister wounds in healthy male and female volunteers

Introduction TCP-25 gel is intended for use in treatment of wound infection and inflammation. Current local therapies for wounds have limited efficacy to prevent infections and there are no wound treatments available today that target the excessive inflammation that often hampers wound healing in both acute and chronic wounds. There is therefore a high medical need for new therapeutic alternatives

Frequent body position changes and physical activity as effective as standard care for infants hospitalised with acute respiratory infections - a randomised controlled trial

Background: No definite consensus has been reached yet on the best treatment strategy for the large group of infants hospitalised with bronchiolitis or pneumonia. Minimal handling is often recommended, although not evaluated scientifically. There is a need to evaluate the management, as the infants often are critically affected, and the costs for society are high. The aim of this RCT was to evalua

"En helt annan upplevelse" : Ljudbokens band till sina läsare

Audiobooks have in recent years become widely popular. The format accordingly impacts how many contemporary readers use and experience literature. The article examines this tendency, departing from Rita Felski’s theoretical conceptualizations of uses of literature (Felski 2008). Felski represents a new attention within literary studies toward the ways in which so-called lay readers use, experience