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This paper is a discussion of theory and methods used in intrasite spatial analysis - the analysis of "living floors". Processes in the formation of the archaeological record such as abandonment, discard, loss, and caching, are discussed. There is also some investigation into factors which may disturb or obscure patterning on an occupation site. Examples to illustrate the discussion are taken from
-Carotid intima-media thickness (cIMT) is a marker of subclinical atherosclerosis that can predict cardiovascular disease (CVD) events over traditional risk factors. This study examined the BCAR1-CFDP1-TMEM170A locus on chromosome 16, associated with cIMT and coronary artery disease in the IMPROVE cohort, to identify the functional variant.
Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable. Understanding the genetic contribution to metformin response might increase the possibility of personalising metformin treatment. We aimed to establish the heritability of glycaemic response to metformin using the genome-wide complex trait analysis (GCTA) method.
Airway challenge with dsRNA is of interest since this agent acts on TLR3 and mimics rhinoviral (RV) infection-induced interferons/cytokines. Contrasting frequent employment of dsRNA in epithelial cell cultures there is no information on effects of dsRNA administered to human airways in vivo. Here we explore effects of nasal dsRNA challenges in subjects with seasonal allergic rhinitis inside and ou
Immigrant populations from the Middle East develop diabetes earlier than indigenous European populations; however, the underlying etiology is poorly understood. This study looked at the risk factors associated with early diabetes onset and, in non-diabetics, glycaemic control in immigrants from Iraq compared with native Swedes.
Red cell distribution width (RDW) has been associated with venous thromboembolism (VTE), but whether RDW is a predictor of first event of VTE is unknown. We investigated the association between RDW and incidence of first event of VTE in a population-based cohort.
-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.
World Health Organization (WHO) has in 2013 changed the diagnostic criteria for gestational diabetes mellitus (GDM) to acknowledge the putative importance of mildly elevated fasting plasma glucose (FPG) levels on pregnancy outcomes. We aimed to determine the prevalence and risk factors of GDM using the previous WHO 1999 versus WHO 2013 criteria in North India.
The article treats the problem why a descriptive grammar cannot avoid from being normative in some ways. some uses of language are always excluded. on the other hand a descriptive grammar should account for competing variants where there might be disagreement among the language users which expression is correct, i.e. should be accepted as norm. The descriptive grammar does not tell which variant i
Atlantic salmon (Salmo salar) from the Baltic Sea suffer from a reproduction disease known as the M74-syndrome. Newly hatched fry develop nerve disorders and die between 3-5 days after the first symptoms are seen. This is a maternally transmitted disease that is casued by a thiamine (vitamin B1) deficiency. The factor(s) that casue(s) this thiamine deficiency are largely unknown. However, several
