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Sociala hänsyn vid offentlig upphandling är ett komplicerat rättsområde. Konceptet har huvudsakligen utvecklats i EU-domstolens praxis men har också kommit att integreras direkt i direktivs- och lagtext. Via implementeringen av 2014 års upphandlingsdirektiv i form av den nya Lagen om offentlig upphandling har den svenska nationella rätten kommit att förändras. Syftet med det här dokumentet är att

Den svenska sexualbrottslagstiftningen har genomgått stora förändringar över åren. Våldtäktsbestämmelsen har på olika sätt utvidgats och tvångskravet har sänkts med tiden. Syftet har delvis varit att förstärka och tydliggöra rätten till sexuellt självbestämmande och sexuell integritet. Detta är två begrepp som har varit återkommande i sexualbrottslagstiftningen under senare år. Trots detta har två

Till följd av den digitala ekonomins framfart de senaste decennierna står det internationella skattesystemet inför flertalet stora utmaningar. De gällande principerna inom den internationella skatterätten har ställts på sin spets då nutidens företag i allt större utsträckning är digitala. Enligt principer inom den internationella skatterätten måste ett företag i dagsläget ha en grad av fysisk närvDue to the progress of the digital economy over the last decades, the international tax system is now facing several substantial challenges. The current principles within international taxation law have consequently been pushed to their edge as a result of the digitalization of present-day companies. According to current principles within international tax law, enterprises must have a degree of ph

The field of genetics has come to rely heavily on commercial genotyping arrays and accompanying annotations for insights into genotype-phenotype associations. However, in order to avoid errors and false leads, it is imperative that the annotation of SNP chromosomal positions is accurate and unambiguous. We report on genomic positional discrepancies of various SNP chips for human, cattle and mouse

Community screening to guide preventive interventions for acute aortic disease has been recommended in high-risk individuals. We sought to prospectively assess risk factors in the general population for aortic dissection (AD) and severe aneurysmal disease in the thoracic and abdominal aorta.

Skiljeförfarande som tvistlösningsform har blivit allt vanligare mellan kommersiella parter, till stor del på grund av dess effektivitet och slutgiltighet. Skiljedomar kan enbart upphävas enligt ett begränsat antal grunder i 34 § 1 st. lag (1999:166) om skiljeförfarande (LSF). En av dessa klandergrunder kan åberopas om skiljenämnden begått ett handläggningsfel utan parts vållande som sannolikt påv

The purpose of the thesis is to explore customer expectations and experiences towards in-store applications and compare those in order to see if there are any gaps. The study is based on qualitative methodology and abductive research approach, enhancing the in-depth understanding of the phenomenon of the in-store applications. 14 semi-structured video interviews of 26-50 min duration were conducte

Trots att forskningen kring transpersoner har ökat exponentiellt de senaste decennierna så vet vi fortfarande lite om den könsbekräftande vården utanför samhällets dominerande institutioner. Utifrån gruppintervjuer och självbiografiska inslag möjliggör denna uppsats en ökad förståelse för de som utför hormonbehandlingar utanför det officiella vårdsystemet. Uppsatsen fokuserar främst på hur den sve

To examine whether undetectable high sensitivity troponin T (hsTnT) can be used to safely rule out non-ST-elevation acute coronary syndrome (NSTE-ACS) (using the limit of detection (LOD) as the cut-off) and to compare this strategy to serial hsTnT and the use of combined hsTnT and copeptin.

The Lifestyle Interventions for Expectant Moms (LIFE-Moms) Consortium is designed to determine, in pregnant women with overweight or obesity, whether various behavioral and lifestyle interventions reduce excessive gestational weight gain (GWG) and subsequent adverse maternal and neonatal outcomes and obesity in offspring. The design and planning process of the LIFE-Moms Consortium is described.

Supplemental Instruction (SI) is an academic support model with large international prevalence with the purpose of preventing dropouts and strengthen students’ study abilities and results. SI is a collaborative form of learning in groups of about 5-15 students who meet on a weekly basis under the facilitation of an SI-leader, an older student with good insight in the course. The SI-leader helps th

Insulin secretion is enhanced upon the binding of Glucagon-like peptide-1 (GLP-1) to its receptor (GLP1R) in pancreatic β cells. Although a reduced expression of GLP1R in pancreatic islets from type 2 diabetic patients and hyperglycaemic rats has been established, it is still unknown if this is caused by differential DNA methylation of GLP1R in pancreatic islets of type 2 diabetic patients.

IL-25 has been implicated in the initiation of type 2 immunity and in the protection against autoimmune inflammatory diseases. Recent studies have identified the novel innate lymphoid type 2 cells (ILC2s) as an IL-25 target cell population. The purpose of this study was to evaluate if IL-25 has any influence on atherosclerosis development in mice.

Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.