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Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question

Background: Oral antigoagulation treatment (OAT) with warfarin have a narrow therapeutic window and patients exhibit a highly variable doseresponse that is attributable to genetic, disease-related,and environmental factors as well as prescription and nonprescription drugs, dietary vitamin K and alcohol. The effect of warfarin treatement on blood coagulation is measured using international normaliz

A matter of life and health : Life satisfaction, personality and mortality in two populations of elders

The aims of the present thesis were to explore and describe elderly people’s morbidity and experience of symptoms in relation to life satisfaction, personality and mortality. (I, II and III) To learn from the individuals who have high life satisfaction in spite of the fact that they have concurrent medical diagnoses and conditions. (I and III) To reason how positive factors and strengths might hel

Genetic factors in primary hypertension- with emphasis on renal sodium reabsorption

Genetic factors are of importance for the development of primary hypertension (HT). Intrauterine growth retardation, salt sensitivity and insulin resistance are all characteristic features of individuals prone to develop HT. Monogenic forms of hypertension such as Liddle´s syndrome (LS) and Apparent Mineralocorticoid Excess (AME), and hypotension such as Gitelman´s syndrome (GIT) have recently bee

CHRONIC MUSCULOSKELETAL PAIN. Population studies of pain-experience with special focus on the Total Body Pain and aspects of adaptation in a cognitive-behavior psychological frame of reference

Musculoskeletal pain-related vocational dysfunction is a major public health problem. The solution is beyond the scope of biomedicine, but the problem could well be analyzed in the complementary, cognitive-behavior psychological frame of reference. In order to better prevent the development of pain-related dysfunction: The sociodemographic milieu of dysfunctional chronic pain patients was examined

Ecology of zooplankton communities: climate, dormancy, and benthic-pelagic coupling

This thesis describes how influences, such as top down and bottom up forces, shape zooplankton communities in shallow lakes. I have also extended the traditional food-web theory by investigating the effects of climate on total biomass, taxonomic composition, and temporal properties of zooplankton communities. A field experiment showed that the total biomass of both phytoplankton and zooplankton in

Word

The paper is an investigation of the concept "word".