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Accelerator mass spectrometry (AMS) is a highly sensitive technique to count atoms. The method has a high efficiency, which makes it possible to measure small samples in a relatively short time, usually less than an hour. During the work for this thesis, methods have been developed to detect Al-26 at the Lund AMS facility. This includes the design, installation and testing of a new injector that i

Hereditary cystatin C amyloid angiopathy (HCCAA) is a disorder characterised by multiple strokes in young adults, resulting in paralysis and dementia. The disease is caused by a mutation in the gene coding for the peptidase inhibitor cystatin C. The mutation causes an amino acid substitution Leu68 -> Gln in cystatin C (L68Q cystatin C) which results in deposition of the protein in the blood vessel

An influential interpretation of the strong growth performance in Western Europe in the 1950s and 1960s stresses the importance of wage restraint, trade unions holding back wages to increase investments. This article questions that interpretation, using a wage regression approach with eighty-five to ninety-six years of data on wages, inflation, unemployment, productivity, and other variables in De

Abstract in Uncoded languages Praegune kaitsejalatsite testimise standard (EN 344) kontrollib soojapidavuslikke omadusi vaid jalatsi ühes punktis, mõõtes temperatuuri muutust. Meetod, mis kasutab termilist jala mudelit, võimaldab mõõta jalatsi soojaisolatsiooni üheaegselt erinevates piirkondades ning ühtlasi ka jalatsi kui terviku soojaisolatsiooni. Selle uurimuse käigus arendati termilise jala mePresent standard on safety footwear (EN 344) checks the insulation only at one point in the shoes by means of measuring the temperature change. A method that uses thermal foot model allows to measure footwear insulation simultaneously at various locations and for whole footwear as well. In the present work the method of heated foot model was developed further. It is possible to simulate sweating a

Previous studies have shown increased cardiovascular mortality as late side effects in Hodgkin lymphoma (HL) patients. This study identifies stratifying risk factors for surveillance and defines concepts for a clinical feasible and noninvasive prospective protocol for intervention of cardiovascular side effects. HL patients diagnosed between 1965 and 1995 (n = 6.946) and their first-degree relativ

The aim of this study was to examine how professionals working in residential care units for unaccompanied children, construct and understand integration and culture. The study was built on empirics which was the result of five semi-structured interviews held with professionals working in this field. The interviews included both professionals working in the public sector and professionals working

Till skillnad från effekter förknippat med övergödning och marin plast, är få medvetna om den negativa miljöpåverkan sandmuddring kan ha på de marina ekosystemen. Sandmuddring ger stora förluster i livsmiljö, förändringar i salthalt och ökad grumlighet vilket utgör ett potentiellt hot mot ett stort antal marina och bräckvatten arter. Ännu värre är det faktum att få människor vet att sandutvinning Unlike effects associated with eutrophication and marine plastics, few are aware of the negative environmental impacts sand dredging can have on marine ecosystems. Major habitat losses, changes in salinity and increased turbidity impose a potential threat to a large variety of marine and brackish species. Even worse is the fact that few people know that sand extraction currently is taking place wi

Autoimmunity, such as type 1 diabetes (T1D), arises as a result of tolerance breakdown against host tissues, i.e. the β-cells. Central tolerance is established during thymic T cell development and defects in key events during this process could contribute to the pathogenesis of autoimmune diseases. The work presented in this thesis was aiming at unravelling some of those aspects. We have investi

The calcium ion (Ca2+) is essential for all plant and animal life. One important function of Ca2+ is as a second messenger in the responses of the cell to environmental and hormonal signals as well as in some intrinsic developmental processes. The intracellular concentration of Ca2+ must be strictly regulated, since a high concentration of free cytosolic Ca2+ is toxic. All eukaryotic cells carry c

In this thesis, I have investigated factors (cues, benefits, and costs) affecting the evolution of an inducible morphological defence in crucian carp (Carassius carassius). Inducible defences are favoured over permanent defences when prey have reliable cues to detect predators, when defences are effective but costly, and when predation pressure is variable and unpredictable, but sometimes s