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Cost differences for COPD with and without physician-diagnosis

Previous studies have presented divergent estimates of the cost of illness of COPD due to differences in methodology. The objective of this study was to examine differences between register-based estimates versus population-based estimates on the burden of COPD. This study therefore examined differences in costs of COPD among physician-diagnosed and un-diagnosed subjects. During a one-year period,

Assessing the Nationwide Impact of a Registry-Based Randomized Clinical Trial on Cardiovascular Practice

BACKGROUND: Registry-based randomized clinical trials have emerged as useful tools to provide evidence on the comparative efficacy and safety of different therapeutic strategies. However, it remains unknown whether the results of registry-based randomized clinical trials have a sizable impact on daily clinical practice. We sought, therefore, to describe the temporal trends in thrombus aspiration (

Serum uric acid in traditional Pacific Islanders and in Swedes.

Background. In some western populations, increased serum uric acid has been positively associated with cardiovascular disease, possibly because hyperuricaemia could be an untoward part of the insulin-resistant metabolic syndrome. However, there is evidence that uric acid is a free radical scavenger capable of inhibiting LDL oxidation. Amongst the traditional horticulturalists of Kitava, Trobriand

Inter-population variations in concentrations, determinants of and correlations between 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE): a cross-sectional study of 3161 men and women from Inuit and European populations

BACKGROUND: The study is part of a collaborative project (Inuendo), aiming to assess the impact of dietary persistent organochlorine pollutants (POPs) on human fertility. The aims with the present study are to analyze inter-population variations in serum concentrations of 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE), to assess inter-popul

Djurens skepnader : Närhet och distans i diskurs och livsvärld

Popular AbstractI denna avhandling studeras förhållandet mellan människa och djur, i synnerhet människans relation till lantbrukets djur. Med teoretiska perspektiv från socialkonstruktivism och existentiell fenomenologi behandlas frågor om hur djur och nötkreatur (som utgör en fallstudie) framträder i diskurser och hur de ingår i bönders livsvärldar. Utifrån debatterna om belgisk blå, BSE (galna kThis dissertation is concerned with the relationship between humans and animals. In particular, it explores human relations to farm animals, and especially cattle. The empirical and theoretical work is concerned with how animals appear in discourses and how they form part of human life worlds. Three debates about recent animal-related issues are examined: the introduction of the cattle breed Belg

Large-scale association study between two coding LRP5 gene polymorphisms and bone phenotypes and fractures in men

Herein we investigated the association between polymorphisms in the LRP5 gene and bone phenotypes and fractures in three large male cohorts based on the rationale that mutations in LRP5 cause severe bone phenotypes. Results showed an association of the Val667Met SNP with spine BMD in 3,800 young and elderly men. INTRODUCTION: The low-density lipoprotein receptor-related protein 5 (LRP5)-Wnt signal