Effects of ethanol on muscarinic acetylcholine receptors in nerve cells
This thesis focused on the mechanisms involved in the effects of long-term ethanol treatment on mAChRs and their coupled-signal transduction pathway in human neuroblastoma SH-SY5Y cells. All 5 subtypes of mAChRs were expressed in these cells. Acute ethanol exposure induced a minor and transient decrease in the number of cell surface mAChRs, which could not account for the previously described pron
