This thesis concerns experimental and theoretical work regarding perpendicular to grain fracture in wooden structural elements. The experimental part concerns strength tests of glulam beams with a hole. The theoretical parts concern development of two models for strength and fracture analysis, both based on fracture mechanics approaches, and their application to analysis of beams with a hole and d

Today’s trends are the ever growing competition with increased globalization and sustainability. Together with ongoing technological developments and the demand for right quality of products and services, this has also resulted in increased demands for legislation and traceability. This development has also had an impact on packaging and Packaging Logistics. This thesis deals with packaging, logis

NADH:quinone oxidoreductase, or complex I, is a large, complex and poorly understood bioenergetic enzyme in the respiratory chain of living organisms. The enzyme has a conserved core structure, comprising fourteen protein subunits: Seven subunits protrude from the membrane and contain a flavin prosthetic group and eight iron-sulfur clusters that guide electrons from the oxidation of NADH towards t

Internal combustion engines have been an important technological field for more than a century. It has had an important impact on society through improved transportation and industrial applications. However, concerns about environmental effects of exhaust gases and utilization of oil resources have pushed development of combustion engines towards cleaner combustion and higher efficiencies. The d

Many scientists believe that the oil production will peak in the near future, if the peak has not already occurred. Peak oil theories and uncertain future oil deliveries have stimulated interest in alternative sources of fuel and chemicals. This interest has been enhanced by concerns about energy security and about the climate change caused by emissions of carbon dioxide. The result has been incre

The industrial use of biocatalysts is increasingly important in the production of e.g. pharmaceuticals, chemicals, fuels and foodstuffs. A successful biocatalytic process is dependent on many factors, such as the biocatalyst properties, the nature of the reaction, reactor type and downstream processing. This work is focused on two important issues: Immobilization of the biocatalyst and in situ pro

Continuum based elasto-plastic-damage models for paperboard have been established in this work. The thesis begins with an introductory section that describes the mechanical properties of paperboard and some of the converting processes during forming of a package. A short review of modeling concepts that have been applied to paperboard is presented and then some key aspects and assumptions develope

This thesis presents the utilization of two different decomposition techniques, proper orthogonal decomposition (POD) and dynamic mode decomposition (DMD), for enhanced understanding of flow structures and their stability. The advantages of these techniques are shown for a range of flow situations, most of which are turbulent. It is shown that by these methods additional insight into complex flow

Infectious pancreatic necrosis virus (IPNV) is a Birnavirus that infects salmonid fish. The infection is usually mortal for fish under six months of age, while older fish become carriers, usually without any signs of infection, and will spread the virus to other susceptible fish and to their offspring. IPNV is an icosahedral, naked virion and the genome consists of two segments of double-stranded

This thesis has two main objectives related to trading foreign currencies. First, it is investigated how the customer order ow of Nordea is related to currency price changes. Second, the goal is to nd a new way of grouping customers that can give additional insights in the trading behaviour of dierent customers. The study uses order ow data which consists of spot and forward transactions made in

It is a widely recognised problem that witnesses are silenced by threat or violence. A number of Nordic countries have therefore chosen to allow anonymous testimony under certain circumstances. The question is if permitting anonymous witnesses are compatible with the principle of the defence, which is governed by the Code of Judicial Procedure and article 6 ECHR that provides right to fair trial.

he hematopoietic development is a highly dynamic but tightly regulated process. The flexibility to produce blood cells through more than one route will allow the blood system to respond rapidly in stress situations such as infections. On the other hand, regulation of the blood system is required to prevent blood cells from uncontrolled proliferation that could result in leukemia or bone marrow fai

Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. Variation in CAG repeat length had been associated with a number of andrological disorders, where

Morphogens such as Hedghog, Wnt, FGF, and retinoic acid are important signals whose concentrations need to be tightly regulated in the vertebrate embryo to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xen

Prostate cancer is one of the most common malignancies. Its treatment is highly dependent on the presence or absence of metastases. The available invasive and non-invasive modalities for detecting metastases are imperfect. Positron-emission tomography fused with computed tomography (PET/CT) is a non-invasive method for detecting metastases that is presently evaluated for prostate cancer. Fluoride