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The role of N-cadherin and S1P/S1P1 in pancreas development

Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. For instance, notochord, endothelial cells, and pancreatic mesenchyme are essential for the development of the pancreas. N-cadherin deficient-embryos suffer fro

Chloride profiling in marine concrete - methods and tools for sampling

This project focuses on how to determine the chloride content in concrete structures exposed to marine environment in an accurate way. When analyzing dust from dry drilling in concrete, it is very often a fact that the chloride profiles show extensive variations even if the sampling has been performed within a very concentrated area with the sampling points close to each other. Several authors hav

Collective Autonomy in the European Union : Theoretical, Comparative and Cross-border perspectives on the Legal Regulation of Collective Bargaining

‘Collective Autonomy in the European Union’ explores the question of collective autonomy by investigating the relationship between collective bargaining and legal regulation and its current evolution in the national contexts and in the EU internal market. The thesis aims at achieving a comprehensive understanding of the notion, function and exercise of collective autonomy and collective bargaining‘Collective Autonomy in the European Union’ explores the question of collective autonomy by investigating the relationship between collective bargaining and legal regulation and its current evolution in the national contexts and in the EU internal market. The thesis aims at achieving a comprehensive understanding of the notion, function and exercise of collective autonomy and collective bargaining

Coordinated Voltage Control in Electric Power Systems

This thesis deals with various aspects of coordinated voltage control in electric power systems. It consists of an introduction and six papers. The introduction contains a summary of the thesis and tutorials on voltage control and the search methods that have been applied. The first part deals with the coordination of cascaded tap changers in radial distribution feeders. A tuning rule for the con

Chronic Obstructive Pulmonary Disease (COPD) Epidemiological and Pan-airway Aspects

Background – Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. However, there is little information on the prevalence and particularly on the incidence of COPD. Also, apart from the importance of tobacco smoking and a1-antitrypsin deficiency, information on contributing risk factors for the development of COPD is limited. Hypotheses – 1. Spirometry

Monitoring insect defoliation in forests with time-series of satellite based remote sensing data - near real-time methods and impact on the carbon balance

Forests are of major importance to climate change mitigation due to their strong capacity to sequester carbon. Nearly half of the terrestrial carbon is stored in forests, and forests contribute to half of the terrestrial primary productivity, with forests in the mid- and high latitude ecosystems as major contributors. These high latitude forests are, however, projected to be strongly influenced by

Radioiodine Therapy of Hyperthyroidism - Simplified patient-specific absorbed dose planning

Radioiodine therapy of hyperthyroidism is the most frequently performed radiopharmaceutical therapy. To calculate the activity of 131-I to be administered for giving a certain absorbed dose to the thyroid, the mass of the thyroid and the individual biokinetic data, normally in the form of uptake and biologic half-time, have to be determined. The biologic half-time is estimated from several uptake