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Protein Complexity via Non-Native States: Binding, Stability, and Structural Studies of Calbindin D9k and HAMLET (Human alpha-lactalbumin Made LEthal to Tumor cells).

Using optical spectroscopy, nuclear magnetic resonance (NMR), and differential scanning Calorimetry (DSC), I have studied two different calcium binding proteins that can form kinetically trapped altered states. Calcium is very important in numerous biological processes such as blood coagulation, signal transduction, muscle contraction and bone formation. Calcium binding to proteins regulates these

Numerical Studies of Mixing in Pipes and Static Mixers

The objective of the present work was to investigate the mixing process in static mixers under laminar flow conditions, and in pipes during the displacement of dissimilar liquids. A numerical scheme and a method of characterizing static mixers were developed. The effects of changes in geometry, flow rate, viscosity ratio and volumetric flow rate ratio on the mixing process were investigated using

Tarot : New age i bild och berättelse

In the course of my dissertation work, I have sought knowledge about what New Age is, contains, and conveys by looking at practice and rhetoric, how the participants act and reason regarding their commitment, as well as how the contents of the field is discussed. I have put an emphasis on the small details: the objects, the rituals, and the narrating. Using the tarot cards as a starting point, the

Gestaltningar av offererfarenheter : Samtal med unga män som utsatts för brott

In this dissertation, young men's experiences of being victims of crime are analysed. Several kinds of material are considered in this study, but the primary data consist of informal, tape-recorded interviews with ten young men (17 to 21 year's old) who had been assaulted or mugged. Their accounts of their experiences are analysed using a number of constructionist, interactionist, and narrative pe

Variationer av predikouppfattningar i Svenska kyrkan. En fenomenografisk undersökning om predikanter och åhörare.

This study describes, systematizes and analyses the variations of preachers' conceptions of their mission to preach and their listeners' conceptions of the sermon. It does so in a phenomenographic and theological perspective. The conceptions of preachers and their listeners of the mission to preach and the sermon respectively are investigated by way of interviews. The basic issues are what differe

Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

Critically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma

A mandibular advancement device reduces sleep disordered breathing in patients with congestive heart failure

Sleep disordered breathing (SDB) including obstructive and central sleep apnoea/ hypopnoea as well as periodic breathing (PB) is common and is believed to increase risk for mortality in patients with congestive heart failure (CHF). Mandibular advancement device (MAD) has widely been recommended for treatment of obstructive sleep apnoea but the method has never been investigated for treatment of SD

Kantor Triple Systems

The main purpose of this thesis is to study real exceptional Kantor triple systems. In the first paper we first prove the known results in both the real and complex classical cases of K-simple Kantor triple systems. In the real classical case our approach gives somewhat simpler formulas. Special attention is given to all real classical cases of K-simple Kantor triple systems that can be presented

Facilitating Transitions to Sustainable Tourism - The role of the tour operator

Tourism has become a leading industry in the world and continues to grow rapidly, contributing essentially to economic growth and employment in many countries. Tourism as it looks today poses serious threats to the environment and considerable social and cultural challenges. The problem addressed by this research lies in the weakness of current concepts and practices in pursuit of sustainable tour

Robin Wood - brittisk filmkritiker

British film critic Robin Wood began to publish on film in 1960. Since then, he has written or co-written 13 books, and also published hundreds of essays and articles in books, in journals, and in different encyclopedias. At the same time, Wood has been a key figure in the development of what has become academic film studies. Wood was educated at Cambridge University, where he studied English lite

Genome Divergence in Progress - a population genetic analysis of the allopolyploid Arabidopsis suecica and its maternal parent A. thaliana

The evolutionary history of the allotetraploid Arabidopsis suecica and its maternal parent Arabidopsis thaliana is analyzed in the thesis in terms of genetic variation in the natural populations of the two species. The earliest phase of the speciation event in which the genomes of A. thaliana and A. suecica are in the process of diverging was investigated using population genetic methods. Evolutio

The Ecophysiology of Arbuscular Mycorrhizal Fungi: Phosphatase Activity Associated with Extraradical and Intraradical Mycelium

Arbuscular mycorrhizal (AM) fungi colonise a wide range of plant species and are especially common in soils with a relatively high pH, where phosphorus availability is a limiting factor for primary production. The aim of this thesis was to study the ecophysiology of arbuscular mycorrhizal (AM) fungi when exposed to different environments. Development of AM fungi and their host plants were investig

Inget landskap är en ö : dialektik och praktik i öländska landskap

The complex character of rural landscapes implies a constant interaction between mind and matter as well as between nature and society. In landscapes, the established division of reality into nature and culture appears all but natural. This book points to the possibilities of regarding landscape as a dialectical process. Landscape is here used as an analytical device to examine nature-culture rela

Quantifying the quality of medical x-ray images. An evaluation based on normal anatomy for lumbar spine and chest radiography.

Optimisation in diagnostic radiology requires accurate methods for determination of patient absorbed dose and clinical image quality. Simple methods for evaluation of clinical image quality are at present scarce and this project aims at developing such methods. Two methods are used and further developed; fulfilment of image criteria (IC) and visual grading analysis (VGA). Clinical image quality de

Potential impact of climate change on European agriculture: a case study of potato and Colorado potato beetle

European agriculture is facing the challenge of managing the impact of climate change on food security. Agriculture in a northern temperate climate is likely to benefit from higher temperature and longer growing season while, in the south, crop productivity is likely to decline. Such changes in climate could also affect the population dynamics of insect pests. The Colorado potato beetle (CPB) is o