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One of the major issues in the pharmaceutical industry today is the cost of development and validation of the production of the active pharmaceutical ingredients. The development, optimization and validation of a production plant have been dominated by an extensive experimental approach. The large amount of experimental work and reluctance for changing existing processes has caused the pharmaceut
Mass corrections and decay constants for light mesons have been calculated in Partially Quenched Chiral Perturbation Theory. The calculations of the charged meson masses have been performed to third order, first for degenerate quark masses, and then, in a second project, for the general case. Another calculation also shows that a resummation of unphysical double poles in the neutral propagators o
Risk analysis and intervention planning are important in fire prevention and risk management strategies. This study has shown that it is possible to use fire safety engineering models to estimate the development of fires on a realistic scale, and the corresponding requirement for extinguishing media. Data from the London Fire Brigade (UK) were used to investigate a possible correlation between the
Although there is a fairly large number of books and articles concerning the validation of technical measurement systems, there are only a few which take into account the whole measurement system consisting of both technical and non-technical aspects. A measurement system comprises both the measurement process and the human being who conducts the measurement. In this way, the human being may be a
The purpose of this thesis is to describe, analyse, and compare the recontextualisation of social pedagogy in three different curricula; in Nijmegen (NL), Lillehammer (N), and Sligo (IRL). The curricula represent different academic orientations and are located in different social-political contexts. The recontextualisation of social pedagogy, the concept derived from the works of Basil Bernstein,
This thesis deals with the recent discourse about Hittite ritual and religion and assumes an alternative approach. It analyses how the most important researchers in the fields of Hittitology and History of Religions, who have been working with Hittite rituals and religion, describe and explain the rituals. Their implicit or explicit theories underlying the discourse are explored. The restraining e
Water column and sediment profiles of plutonium, americium, thorium and uranium have been obtained in the superanoxic Framvaren fjord, southern Norway. The concentrations of bomb test fallout Pu, Am as well as 'dissolved' Th in the bottom water are the highest recorded in the marine environment. The behaviour of the actinides in the anoxic water mass is to a large extent governed by the behaviour
The spectrum and energy levels C IV and the 3l4l' system of the Mg-like ions in the iron group elements has been investigated. This has led to several hundred identified transitions, many of them previously unknown. Using the Charge Exchange diagnostic system at JET, ion temperatures, rotation velocities and densities have been derived from visible spectroscopic measurements on fully ionised light
The principles of sanctity of life and quality of life are often appealed to in medical decisions at the "edges of life." Notwithstanding their importance in bioethics, these principles are still badly understood. This study is an attempt to clarify their normative significance and content. Because these principles pertain to the more general question of the value of life, the study begins by exp
A theoretical and experimental study of rack storage fires and responsiveness of sprinklers is presented. Free-burn tests with non-combustible and combustible material were carried out in reduced scale with verification in large scale. Formulas for in-rack flame height, excess gas temperature, gas velocity and heat flux to storage walls are provided. The formulas include overall heat release rate,
Friction-related problems are frequently encountered in control systems. This thesis treats three aspects of such problems: modeling, analysis, and friction compensation. A new dynamic friction model is presented and investigated. The model is described by a first order nonlinear differential equation with a reasonable number of parameters, yet it captures most of the experimentally observed frict
The aim of this dissertation is to study some of the forces behind the transformation of the 20th century industrialised countryside. The emphasis is on changes in everyday life for women and men, and the role of organisations therein. Two main questions are outlined: Which forces were central to the development of the industrial society?, and, how did the relationship between individual and socie
The work examines developments in the novel and the short story of writers who grew up during the New Order era (1966-1998) in the period of reform post 1998. It is assumed and subsequently affirmed that the genres are developing, modern genres in dialogue with the past and present. The work's main use of theory is that of M. M. Bakhtin's ideas of dialogism. The assumption of 'novelization' is fra
This paper examines the impact of formal and informal institutions on the Chinese music industry. Standard utilitarian theory states that property rights are essential for innovation and this research tests the effects that intellectual property rights has on the Chinese music industry by using panel data on the provincial level for the years 1997 to 2011. In order to further investigate the Chine
