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The possibility that nitric oxide synthase (NOS) inhibitors influence dynorphin immunoreactivity following hyperthermia was examined in a rat model using a pharmacological approach. Previous reports from our laboratory show that hyperthermia induces an upregulation of NOS in several brain regions that seems to be instrumental in causing cell injury. Recent reports suggest that nitric oxide (NO) ca
Severe cerebral intraventricular hemorrhage (IVH) in preterm infants continues to be a major clinical problem, occurring in about 15-20% of very preterm infants. In contrast to other brain lesions the incidence of IVH has not been reduced over the last decade, but actually slightly increased. Currently over 50% of surviving infants develop post-hemorrhagic ventricular dilatation and about 35% deve
Objectives: The progression and pathophysiology of neuropathy in impaired glucose tolerance (IGT) and type 2 diabetes (T2DM) is poorly understood, especially in relation to autophagy. This study was designed to assess whether the presence of autophagy-related structures was associated with sural nerve fiber pathology, and to investigate if endoneurial capillary pathology could predict the developm
Background. Proton therapy of lung cancer holds the potential for a reduction of the volume of irradiated normal lung tissue. In this work we investigate the robustness of intensity modulated proton therapy (IMPT) plans to motion, and evaluate a geometrical tumour tracking method to compensate for tumour motion. Material and methods. Seven patients with a nine targets with 4DCT scans were selected
Characterising the stop/start walking process of individuals in a crowded and congested space is an important consideration in modelling pedestrian movement. However, the reaction of pedestrians to speed changes, especially to the person in front, has not been fully characterised nor quantified for full adoption in computer models. This study, therefore, explored the different phases of the stop/s
Chromosomal aneuploidy, that is, numerical chromosome aberrations, is one of the molecular hallmarks of cancer. However, when neoplasms are studied with sequencing- and array-based approaches, chromosome numbers and ploidy states are typically inferred from bulk DNA data. Furthermore, published molecular estimates of neoplasia-associated aneuploidy often also include genomic imbalances resulting f
Plasmodium berghei is the causative agent of rodent malaria and is widely used as a model system to study the liver stage of Plasmodium parasites. The entry of P. berghei sporozoites into hepatocytes has extensively been studied, but little is known about parasite-host interaction during later developmental stages of the intracellular parasite. Growth of the parasite far beyond the normal size of
Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5+ B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG rearrangements are present in normal B cells as a part of the public IG repertoire. In this study, we collected details on the representation an
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry Exp Brain Res (1988) 73:115-126 E ,x _'mental Bran Research 9 Springer-Verlag 1988 Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxyla
https://www.wnc.lu.se/sites/wnc.lu.se/files/clarke_et_al_exp_brain_res_1988.pdf - 2026-09-19
Popular Abstract in Swedish Datorgrafik handlar om att övertyga betraktaren. En huvuduppgift är att generera verklighetstrogna bilder utifrån tredimensionella modeller. Med hjälp av datorer simuleras hur dessa modeller interagerar med ljus. Betraktaren skall helst inte reflektera över om bilden han ser är ett fotografi eller en helt och hållet genererad bild. I denna avhandling presenteras algoritModern graphics hardware pipelines create photorealistic images with high geometric complexity in real time. The quality is constantly improving and advanced techniques from feature film visual effects, such as high dynamic range images and support for higher-order surface primitives, have recently been adopted. Visual effect techniques have large computational costs and significant memory bandwid
AbstractThe overall aims of this thesis were to use echocardiography to non-invasively, delineate early structural andfunctional changes following orthotopic heart transplantation (OHT), and to define reference values in the contextof gender and bridging with mechanical circulatory support.Several factors might affect myocardial function in OHT patients rendering the use of normal values fortranst
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING (Popularized summary in Swedish) Monoaminer Monoaminer såsom serotonin, dopamin, noradrenalin, adrenalin och histamin är alla signalsubstanser syntetiserade från enkla aminosyror. Nervceller som innehåller monoaminer är anatomiskt lokaliserade till hjärnstammen och förlängda märgen. Härifrån försörjer de resten av storhjärnan samt ryIn the present study, the mRNA encoding the serotonin transporter (5-HTT) and two isoforms of the vesicular monoamine transporters (VMAT1 and VMAT2) have been mapped in the rat throughout gestation and early postnatal development using in situ hybridization, RT PCR and immunohistochemistry. 5-HTT mRNA was found in serotonergic neurons and VMAT2 mRNA in all monoaminergic neurons from early gestatio
Popular Abstract in Swedish Inom sjukvården används strålning för att behandla cancer. Vid strålbehandling är det viktigt att man i förväg vet precis hur strålningen ska ges till patienten för att resultatet av behandlingen skall bli bra. Ett hjälpmedel som används för detta är ett datorprogram (dosplaneringssystem) som, med utgångspunkt från patientens anatomi, beräknar hur varje enskild patient Gel dosimetry is a new dosimetry method applied in radiation therapy. Gel dosimeters consist of a radiation sensitive gel, which can integrate absorbed doses from several radiation sources or beams. The dose to the gel can be evaluated by magnetic resonance imaging (MRI), a procedure that is the focus of the present thesis. A robust tool for the evaluation of the nonuniformity in MRI has been dev
Microsoft Word - STATISTICAL MECHANICS2.doc 31 4. Two-level systems 4.1 Introduction Two-level systems, that is systems with essentially only two energy levels are important kind of systems, as at low enough temperatures, only the two lowest energy levels will be involved. Especially important are solids where each atom has two levels with different energies depending on whether the electron of th
https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2025-01/statistical-mechanics-2.pdf - 2026-09-19
The contribution of this licentiate thesis lies in the modelling of a multi-echelon inventory system with more general backorder cost structures. Backorder costs are traditionally assumed to be linear, whereas we consider structures that are more general functions of the customers’ time in backorder. The system studied is a two-echelon system with one central warehouse and a number of local sites,The contribution of this licentiate thesis lies in the modelling of a multi-echelon inventory system with more general backorder cost structures. Backorder costs are traditionally assumed to be linear, whereas we consider structures that are more general functions of the customers’ time in backorder. The system studied is a two-echelon system with one central warehouse and a number of local sites,
Popular Abstract in Swedish Idag använder många offentliga beslutsfattare en stor andel av sin tid åt att söka introducera nya policies, program och tekniker. Medborgerligt missnöje med offentlig service och offentliga sparbeting gör att många beslutsfattare verkar i en turbulent omvärld, där förändringstrycket är stort. Impulser till policyförändring kan komma från många olika håll. I min studie This thesis discusses an alternative to the conventional policy diffusion approach, i.e. the social constructivist translation perspective. Within the translation perspective, policy diffusion is defined as a process where meaning is constructed by temporally and spatially disembedding policy ideas from their previous context and using them as models for policy change in a new context. This brings
Brevmall Postadress Box 7080 220 07 Lund Besöksadress Tycho Brahes väg 1 Telefon 046-222 09 54 Fax 046-222 34 06 E-post Alf.Rosenback@ehl.lu.se Webbadress http://www.ehl.lu.se Fakul te tss tyre lsen Föreskrifter för utbildning på forskarnivå vid Ekonomihögskolan Detta beslut upphäver tidigare beslut om föreskrifter för forskarutbildningen vid Ekonomihögskolan daterat 2018-04-24, diarienummer STYR
https://www.ehl.lu.se/sites/ehl.lu.se/files/2024-01/ehl-foreskrifter-forskarutbildning-sv.pdf - 2026-09-19
Course Summary for NGEN08 Satellite Remote Sensing Course Summary for NGEN08 Satellite Remote Sensing vt 2020 Course coordinator: Lars Eklundh Teachers in the course: Jonas Ardö, professor (JA) Lars Eklundh, professor (LE) Sofia Junttila, PhD candidate (SJ) Per-Ola Olsson, postdoctoral researcher, (PO) Vaughan Phillips, senior lecturer (VP) Tetiana Svystun (doktorand) (TS) Torbern Ta
https://www.nateko.lu.se/sites/nateko.lu.se/files/2023-02/NGEN08%20Course%20evaluation%20summary%202020.pdf - 2026-09-19
Soil mineral weathering is one of the major sources of base cations (BC), which play a dual role in forest ecosystems: they function as plant nutrients and buffer against the acidification of catchment runoff. On a long-term basis, soil weathering rates determine the highest sustainable forest productivity that does not cause acidification. It is believed that the hydrologic residence time plays a
