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Bleomycin has, in the years of developing electrochemotherapy (ECT), proven to be an extremely potent drug for this cancer treatment modality and is also the most frequently applied chemical agent. It is of importance to investigate the pharmacokinetics of bleomycin under normal conditions and particularly in combination with ECT.

Rats were exposed to insulin-induced hypoglycemia resulting in periods of cerebral isoelectricity ranging from 10 to 60 min. After recovery with glucose, they were allowed to wake up and survive for 1 week. Control rats were recovered at the stage of EEG slowing. After sub-serial sectioning, the number and distribution of dying neurons was assessed in each brain region. Acid fuchsin was found to s

Objectives/Hypothesis: The upper respiratory tract is involved in many acute and chronic respiratory tract diseases that present with the symptom of mucus hypersecretion. Mucin genes that encode for the backbone of glycoproteins contribute to the viscoelastic property of airway mucus. We examined the cellular expression and distribution of two major respiratory mucus-forming glycoproteins, MUC5AC

A two-echelon distribution inventory system with a central warehouse and a number of retailers is considered. The retailers face stochastic demand. The system is controlled by continuous review installation stock (R,Q) policies with given batch quantities. There are linear holding costs at all locations and linear backorder costs at the retailers. We present a simple technique for approximate opti

Background: Heart function following heart transplantation (HTx) is influenced by numerous factors. It is typically evaluated using transthoracic echocardiography, but reference values are currently unavailable for this context. The primary aim of the present study was to derive echocardiographic reference values for chamber size and function, including cardiac mechanics, in clinically stable HTx

We study large n expansions for the partition function of a Coulomb gas (Formula presented.) where Q is a radially symmetric confining potential on the complex plane C. The droplet is not assumed to be connected, but may consist of a number of disjoint annuli and possibly a central disk. The boundary condition is “soft edge”, i.e., Q is smooth in a C-neighbourhood of the droplet. We include the fo

Doctoral Thesis Structural Mechanics Report TV SM -1032 D A V ID K IN SELLA A N N EA LED G LA SS FA ILU R E M O D ELLIN G - A W eakest-Lin k A p p ro ach w ith Statistical A n alysis DAVID KINSELLA ANNEALED GLASS FAILURE MODELLING A Weakest-Link Approach with Statistical Analysis DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS Copyright © David Kinsella 2021. Printed by V-huse

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm1000/web1032.pdf - 2026-09-22

In the recent years, cryptocurrencies have gained popularity and have experienced high price volatility. This essay pretends to examine how the multivariate GARCH models predict the volatility of these digital currencies and what implications exist if we consider the correlations among them to forecast their volatility. Using a bivariate Diagonal VECH and bivariate Diagonal BEKK this thesis checks

Department of Mechanical Engineering Solid Mechanics ISRN LUTFD2/TFHF–06/5118-SE(1-105) ROBUSTNESS ANALYSIS OF FE-MODELS Master’s Dissertation by LINDA NILSSON Supervisors Jan Reger, P+Z Engineering GmbH, Germany Mathias Wallin, Div. of Solid Mechanics, Lund University, Sweden Ulf Nyman, Div. of Solid Mechanics, Lund University, Sweden Copyright c© 2006 by Div. of Solid Mechanics, P+Z Engineering

https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5118.pdf - 2026-09-21

The coupled structure-acoustic problem is studied using the finite element method. An efficient strategy for solving the coupled eigenvalue problem is proposed. The strategy uses a limited number of the uncoupled structural normal modes and acoustic fluid normal modes together with a set of interface-dependant Lanczos vectors for each domain to reduce the coupled problem. The Lanczos vectors are c

This thesis aims at reconstructing events in the solar system, mainly collisional events in the asteroid belt, by searches for extraterrestrial minerals in Paleogene and Middle Ordovician marine sediments on Earth. Recent empirical evidence show that Earth has experienced a few brief periods during the Phanerozoic when the flux of extraterrestrial matter significantly increased. The most prominent

An experimental and numerical study on mechanical properties, such as strength, elastic modulus, creep and shrinkage, of Self-Compacting Concrete, SCC, and the corresponding properties of Normal Compacting concrete, NC, is outlined in this article. The study included eight mix proportions of sealed or air-cured specimens with water-binder ratio, w/b, varying between 0.24 and 0.80. Half of the mixe

ArtOfAstrometryHobbs ART OF ASTROMETRY AND COMPUTATION David Hobbs Lund Observatory 1. Introduction Dynamical astronomy: deals with the determination of the kinematical and dynamical properties of stellar systems (mainly the MW) based on astrometric observations. • Kinematics describes the motion of bodies and systems of bodies without consideration of the forces that cause the motion. It refers t

https://www.astro.lu.se/sites/astro.lu.se/files/2024-06/ArtOfAstrometryHobbs.pdf - 2026-09-30

Popular Abstract in Swedish Bakgrunnen for den foreliggende avhandling er et ønske om å utnytte moderne tredimensjonell bildeanalyse for å forbedre undersøkelse og tolkning av synsnervehodets (papillens) form og størrelse (topografi). Synsnervehodet representerer den delen av synsnerven som trer inn i bakre del av øyet gjennom senehinnen (sklera). Den normale synsnerve har ca 1.2 millioner nervetrEvaluation of the optic nerve head topography is one of the most important methods to diagnose and monitor patients with glaucoma. Until recently, optic nerve head topography has most often been judged by either ophthalmoscopy or from optic disc photographs. These methods are subjective and examiners do not have access to absolute measurements of the optic disc size and cup depth. The result of su

Licentiate Dissertation Structural Mechanics DAVID KINSELLA Report TV SM -3079 D A V ID K IN SELLA M O D ELLIN G O F A N N EA LED G LA SS FR A C TU R E MODELLING OF ANNEALED GLASS FRACTURE DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--18/3079--SE (1-227) | ISSN 0281-6679 ISBN 978-91-7753-760-1 (Print) | 978-91-7753-761-8 (Pdf) LICENTIATE DISSERTATION Copyri

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm3000/web3079.pdf - 2026-09-22

The presence of immunoreactive pancreatic secretory trypsin inhibitor (irPSTI) was studied using an immunohistochemical method in normal and diseased gall bladder and normal and neoplastic colonic mucosa. Normal and inflammatory gall bladder mucosa did not stain for irPSTI. Neoplastic gall bldder mucosa showed positive staining for irPSTI, with a more pronounced staining in well rather than in poo

Ischaemic retinal cell degeneration seems to involve both NMDA and non-NMDA receptor over-stimulation. However, different retinal cell types differ largely in their susceptibility to excitatory amino acid-induced neurotoxicity. We have investigated the vulnerability of GABAergic cells in the rabbit retina to the non-NMDA receptor agonist kainic acid (KA). The distribution of GABA immunoreactivity