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For a CD8 epitope-based vaccine to match different geographic locations, the targeted epitopes for cytotoxic T-lymphocytes (CTLs) must be present in the local circulating HIV-1 strains. Secondly, the vaccine epitopes should match the host population HLA types. We characterized two new HIV-1 isolates from Guinea-Bissau. Also, we have identified 15 subdominant CD8 epitopes representing common HLA su

Central nervous system (CNS) involvement is rare in patients with Hodgkin lymphoma (HL). Thus, the clinical features and outcomes are not well described. Cases of histologically confirmed CNS HL diagnosed between 1995 and 2015 were retrospectively identified in institutional (n = 7), national (n = 2), and cooperative group (n = 1) databases. We screened 30,781 patients with HL in our combined data

BackgroundShock is a condition with high mortality even with early intervention and treatment. Usual care for shock and hypotension in the Emergency Department (ED) is intravenous fluid resuscitation which can lead to fluid overload and other complications. When fluid therapy fails or risk of complications are high, the next treatment step is the use of vasopressors for stabilisation. Noradrenalin

Early life air pollution exposure may play a role in development of respiratory infections, but underlying mechanisms are still not understood. We utilized data from two independent prospective birth cohorts to investigate the influence of prenatal and postnatal ambient air pollution exposure of PM2.5, PM10 and NO2 on maternal and child proteomic profiles and the risk of daily diary-registered com

Heat-shock protein 90 (HSP90) is a molecular chaperone that activates oncogenic transformation in several solid tumors, including lung and breast cancers. Ganetespib, a most promising candidate among several HSP90 inhibitors under clinical trials, has entered Phase III clinical trials for cancer therapy. Despite numerous evidences validating HSP90 as a target of anticancer, there are few studies o

PURPOSE: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients.METHODS: International 1-day point-prevalence study; follow-up for outcome assessment unti

Changes in gene regulation and expression govern orderly transitions from hematopoietic stem cells to terminally differentiated blood cell types. These transitions are disrupted during leukemic transformation, but knowledge of the gene regulatory changes underpinning this process is elusive. We hypothesized that identifying core gene regulatory networks in healthy hematopoietic and leukemic cells

Introduction: Survival in patients with cyanotic congenital heart disease (CCHD) has improved dramatically. The result is an ageing population with risk of acquired heart disease. Previous small uncontrolled studies suggested that these patients are protected against the development of atherosclerosis. To test this hypothesis, we sought to determine the prevalence of subclinical atherosclerosis in

Språk- och litteraturcentrum Författarskolan Kurslitteratur för FSPA01 Skrivandets pedagogik: praktiska och teoretiska förhållningssätt, 3 hp, ht 2025 (Fastställd i Sektionsstyrelse 2, SOL-Centrum, 2 juni 2025) Hoel, Torlaug Løkensgard (2001), Skriva och samtala: lärande genom responsgrupper, Lund: Studentlitteratur (278 s.) Nyberg, Fredrik (2016), Den mjuka texten, Göteborg: Göteborgs universite

https://www.sol.lu.se/media/utbildning/dokument/kurser/FSPA01/20252/Litteratur_FSPA01_HT25_1.pdf - 2025-11-01

If a residence permit cannot be awarded on other grounds, a permit may, according to chapter 5.6 in the Aliens Act, be granted to an alien if there are exceptionally distressing circumstances. Since July 2014, children may be granted permits if the circumstances are particularly distressing. Prior to July 2014, both children and adults needed to meet the criteria exceptionally distressing circumst

The Swedish rape law was changed on July 1st, 2013, through the introduction of the concept ”particularly vulnerable situation” that replaced the former wording ”helpless state”. The reason behind this change was that the courts had applied the concept helpless state narrowly. The demands were too high for someone to be in a helpless state. These deficiencies occurred particularly when applying th

Varumärkesförfalskning är idag ett allmänt förekommande problem. Utbredningen av förfalskade varor riskerar att minska incitamenten att investera och bygga upp varumärken, på samma sätt som incitamenten att investera i och utveckla läkemedel skulle minska om möjligheten till patent försvagades. Varumärkesförfalskning är ett problem för både konsumenter och näringsidkare. Konsumenterna riskerar attCounterfeiting in gods is a fast growing issue affecting both consumers and businesses worldwide. Consumers might mistake a fake with the original product and traders threaten to weaken their brands and the sale is lost in favour of the counterfeit gods. In the long run the expansion of counterfeiting gods might lead to less incentives for businesses to invest and develop trademarks. From the firs

Metan (CH₄) är en av de viktigaste växthusgaserna i atmosfären och dess kraftiga ökning har bidragit till den uppvärmning som vi har upplevt fram till idag. Sedan mitten av 1980-talet påvisar mätningar att metantillväxten i atmosfären har börjat fluktuera från år till år. Orsakerna till detta är omstridda och ännu inte klargjorda. Under 2007 uppmättes en kraftig ökning i tillväxt som vaThe increasing atmospheric concentration of the greenhouse gas methane (CH₄) is highly relevant for current and future global warming. Since the mid-1980s atmospheric measurements have revealed large interannual fluctuations in methane growth rate. However, the causes of this feature are still not well understood. In 2007, a peak in growth rate appears to have been particularly strong a

I de flesta av EU:s medlemsstater kan bolag inom samma koncern resultatutjämna mellan sig. Förutsatt att bolagen har hemvist i samma medlemsstat kan ett bolag som går med vinst utjämna denna mot ett annat koncernbolags förluster. På så vis blir koncernen beskattad för sitt nettoresultat och skattebelastningen blir varken högre eller lägre än om verksamheten hade bedrivits inom ett enda bolag istälMost EU Member States have tax systems allowing domestic groups of companies to offset their losses both horizontally and vertically within the group. Since the groups will be taxed on their net result, the overall tax burden is neither higher nor lower than if carried out within a single company. If, however, the group chooses to establish a company in another Member State, it looses the right t

Abstract Författare: Patric Andersson Titel: Nya tider, nya skatter – en studie om efterfrågans priskänslighet på flygmarknaden i regionen kring Malmö-Sturup Handledare: Krister Hjalte Uppsats NEK 691 Nationalekonomiska institutionen Ekonomihögskolan Lunds universitet Höstterminen 2005 I uppsatsen behandlades nuvarande situation och de senaste årens utveckling på flygmarknaden med tyngdpunkt på de

1 IAC ANNUAL REPORT 2022 _____________________________________________________________________________________________________ 1 | welcome 2 | about 3 | brief facts 4 | artistic research fields at iac 5 | collaborations with the academies 6 | collaborations with lund university 7 | co-localisation: new artistic campus 8 | external collaborations 9 | residencies 10 | long-term collaborations 11 | f

https://www.iac.lu.se/sites/iac.lu.se/files/2023-10/IAC%20ANNUAL%20REPORT_2022_FINAL_VERSION_SMALL.pdf - 2025-11-03

Since July 1, 2013, there is no longer a sterilization requirement for transgender persons who want to transition. This paper critically examines the new legislation in the Parental Code, which entered into force on January 1, 2019 as a result of the abolished sterilization requirement. The new legislation applies to parenthood when one or both parents have changed their legal gender. Before the n

Abstract Title: IFRS 15 - Full or Modified Retrospective Application? A study of the standard’s effects and the factors behind companies’ choice of transition method. Seminar date: June 2nd, 2021 Course: FEKH69, Degree Project Undergraduate level, Business Administration, 15 University Credits Points (ECTS) Authors: Julia Baeza, Vendela Barth and Felicia Sonesson Advisor: Kristina Artsberg Key wor

On the first of July, 2021, it became a crime in Sweden to allow children to witness crimes between relatives. The crime is called ”barnfridsbrott” and exists in Chapter 4, Section 3 in the Swedish Criminal Code. The criminalization of allowing children to witness crimes between relatives was met with a positive response from most of the consultation bodies. Although it was welcomed with open arms

As a result of the increased gang violence in Sweden, a crown witness system was introduced on July 22, 2022, which has been widely criticized. However, the legislator considered such regulation to be predominantly necessary. By introducing a new paragraph, ch. 29 § 5 a in the Swedish Criminal Code, the legislation can be described as an attempt to escape the culture of silence and initiate an eff