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The gp130 receptor and its binding partners play a central role in cytokine signalling. Ciliary neurotrophic factor (CNTF) is one of the cytokines that signals through the gp130 receptor complex. CNTF has previously been shown to be a negative regulator of trabecular bone remodelling and important for motor neuron development. Since haematopoietic cell maintenance and differentiation is dependent

Vi lärare på Litteraturvetenskapliga institutionen vid Lunds universitet har länge saknat ett arbetsmaterial när vi undervisat i hur man utför epikanalyser. Det har visat sig att Claes-Göran Holmbergs och Anders Ohlssons Epikanalys. En introduktion har fungerat utmärkt som lärobok och på ett enkelt sätt utrett de många teorier och metoder som kan utnyttjas i en analys. Men våra erfarenheter av epi

The interplay between diet and immune-parameters which could affect type 1 diabetes (T1D) pathogenesis is not sufficiently clarified. Intestinal upregulation of the activating receptor NKG2D(CD314) and its ligands is a hallmark of celiac disease (CD). However, the direct effect of gluten on NKG2D expression is not known. We studied, by FACS (lymphoid tissues) and RT-qPCR (intestine and pancreatic

Background and purpose — High alcohol intake is associated with increased risk of postoperative complications. Alcohol cessation intervention is recommended prior to elective surgery. We investigated short- and long-term effects of perioperative intensive alcohol intervention in relation to acute ankle fracture surgery.Patients and methods — 70 patients requiring ankle fracture surgery and consumi

BRCA1-associated protein 1 (BAP1) is a nuclear deubiquitinating enzyme that is associated with multiprotein complexes that regulate key cellular pathways, including cell cycle, cellular differentiation, cell death, and the DNA damage response. In this study, we found that the reduced expression of BAP1 pro6motes the survival of neuroblastoma cells, and restoring the levels of BAP1 in these cells f

Digital media have provided new avenues of distribution for serial fiction and created new narrative possibilities for the form, including the widespread use of what Margolin labels "concurrent narration" and Page terms "real-time narration." This form of serial publication, where a story is distributed in installments coterminously with the events being reported, is enabled by the Internet's poss

The structural addictive characteristics of gambling products are important targets for prevention, but can be unintuitive to laypeople. In the PictoGRRed (Pictograms for Gambling Risk Reduction) study, we aimed to develop pictograms that illustrate the main addictive characteristics of gambling products and to assess their impact on identifying the addictiveness of gambling products by laypeople.

INTRODUCTION: Type 1 diabetes (T1D) is caused by the destruction of pancreatic islet beta cells resulting in total loss of insulin production. Recent studies have suggested that the destruction may be interrelated to plasma lipids.OBJECTIVES: Specific lipids have previously been shown to be decreased in children who develop T1D before four years of age. Disturbances of plasma lipids prior to clini

sfla !-ozt |l ftO ft LUNDS UNIVERSITET Sociologiska Institutionen Protokoll institutionsstyrelsen Sammansträdesdatum 2024-03-07 Närvarande i mötesrum: Allhelgonaskolan, 118 Magnus Karlsson, ordf. Lisa Flower, lärarrep./SOC Erik Hannerz, lärarrep./SOC Fredrik Sandberg, lärarep.(SOC Johan Sandberg, 1ärarrep./SOC, fr.o.m. $5 Nina Gren, lärarrep./SAN Caroline Spannel Brnelic, rep. TA Anton Petersson,

https://www.soc.lu.se/internt/sites/soc.lu.se.internt/files/2024-03/Styrelseprotokoll%202024-03-07.pdf - 2025-10-20

Alfabetisk förteckning över tidningslägg i stort format som är i så dåligt skick att de inte kan plockas fram Rödmarkerade tidningar finns dock på mikrofilm Aftonbladet 1866-1868, 1870-1877, 1879-1880, 1882-1909 Aftonbladet 1891-1896 Vecko uppl Annonsblad till tidskrift för lantmän 1884-1925 Arvika Tidning 1900-1903 Avesta Tidning 1912-1919,1921-1923 Barometern 1891-1908 mars. Bergslagernas Tidnin

https://www.ub.lu.se/sites/ub.lu.se/files/forteckning-tidningar-oplockbara-2017-03-21.pdf - 2025-10-20

Vår undersökning har kommit fram till att det existerar vissa anomalimönster på Stockholms fondbörs under åren 1980-2002. Vi har kunnat konstatera att aktieavkastningarna i regel har varit högre i början av året jämfört med sista delen av året. Vi har även observerat en förändring samt mer tydliga anomalimönster under 1990-talet. Detta påvisas både i vår studie av 15-15 månadsavkastningar samt i v

Aquaporins (AQPs) are water channels embedded in the cell membrane that are critical in maintaining water homeostasis. We describe a protocol for determining the water permeation capacity of AQPs reconstituted into proteoliposomes. Using a stopped-flow setup, AQP embedded in proteoliposomes are exposed to an osmogenic gradient that triggers water flux. The consequent effects on proteoliposome size

Aquaporin water channels (AQPs) are membrane proteins that maintain cellular water homeostasis. The interactions between human AQPs and other proteins play crucial roles in AQP regulation by both gating and trafficking. Here, we describe a protocol for characterizing the interaction between a human AQP and a soluble interaction partner using microscale thermophoresis (MST). MST has the advantage o

Identification of determinants of fate choices in hematopoietic stem cells (HSCs) is essential to improve the clinical use of HSCs and to enhance our understanding of the biology of normal and malignant hematopoiesis. Here, we show that high-mobility group AT hook 2 (HMGA2), a nonhistone chromosomal-binding protein, is highly and preferentially expressed in HSCs and in the most immature progenitor

We consider Bayesian inference for stochastic differential equation mixed effectsmodels (SDEMEMs) exemplifying tumour response to treatment and regrowth in mice. We produce an extensive study on how an SDEMEM can be fitted by using both exact inference based on pseudo-marginal Markov chain Monte Carlo sampling and approximate inference via Bayesian synthetic likelihood (BSL). We investigate a two-

1 Utbildningsplan 1. IDENTIFIKATION • Programmets namn och inriktning: musikerutbildning, symfoniorkesterinstrument. • Omfattning i högskolepoäng: 180. • Nivå: G. • Programkod: KGMUS. Inriktning: SYMF. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 11 augusti 2008. Utbild­ ningsplanen träder i kraft den 11 augusti 2008. 2. PROGRAMBESKRIVNING Musikerutbildning, symfoniorkeste

https://www.mhm.lu.se/en/sites/mhm.lu.se.en/files/kgmus_symf_sve_uppdaterad.pdf - 2025-10-20