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Geometry, Reduction Potential, and Reorganization Energy of the Binuclear CuA Site, Studied by Density Functional Theory

Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin EP4-R essential for agonist-induced beta-arrestin1 recruitment that differs from the apparent principal phosphorylation site.

hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a Gs-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend on the presence of its C-terminal domain. Desensitization and internalization of GPCRs are often linked to agonist-induced b-arrestin complex formation, which is stabilized by phosphorylation. Subsequentl

Prospects for a regional assessment of forest soil chemistry dynamics in Croatia: Application of the SAFE model to a forested site in the region of Mt. Medvednica

Unusual CO adsorption sites on vanadium oxide-Pd(111) "inverse model catalyst" surfaces

The morphology, structure, and reactivity of vanadium oxide-decorated Pd(111) surfaces, which have been subjected to oxidation and reduction treatments, have been investigated by scanning tunneling microscopy (STM), high-resolution electron energy loss spectroscopy (HREELS), and high-resolution X-ray photoelectron spectroscopy (HR-XPS) with synchrotron radiation combined with ab initio density fun

Persistent organochlorine pollutants in children working at a waste-disposal site and in young females with high fish consumption in Managua, Nicaragua

No difference between daily and weekly pin site care: a randomized study of 50 patients with external fixation.

The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function

Accurate Predictions of Nonpolar Solvation Free Energies Require Explicit Consideration of Binding-Site Hydration

Continuum solvation methods are frequently used to increase the efficiency of computational methods to estimate free energies. In this paper, we have evaluated how well such methods estimate the nonpolar solvation free-energy change when a ligand binds to a protein. Three different continuum methods at various levels of approximation were considered, viz., the polarized continuum model (PCM), a me

Available energy and energy balance closure at four coniferous forest sites across Europe

The proper way of dwelling at the Early Neolithic gathering site of Almhov in Scania, Sweden

Effects on rural House Sparrow and Tree Sparrow populations by experimental nest-site addition

Do quantum mechanical energies calculated for small models of protein-active sites converge?

Short- and midterm results of the fascia suture technique for closure of femoral artery access sites after endovascular aneurysm repair.

Postoperative gastrostomy site leakage correlated to the dimension of the gastrostomy button in children

Age estimation of wild boar (Sus scrofa) based on molariform mandibular tooth development and its application to seasonality at the Mesolithic site of Ringkloster

Localization of functional sites in the viral complement inhibitor KCP

Kaposi's sarcoma-associated herpes virus (KSHV) encodes a complement inhibitor named KSHV complement control protein (KCP). We have previously shown that KCP inhibits the human complement system by disrupting the C3 convertase of complement. KCP can accelerate the decay of the classical C3 convertase and it can act as a cofactor for factor I (R), which then cleaves and inactivates C4b or C3b (in t

Tracking taphonomy. Analysis of skeletal remains from wild boar (Sus scrofa) and red deer (Cervus elaphus) from Mesolithic sites in Scania, Southern Sweden

Determination of NO adsorption sites on Pd(100) using core level photoemission and low energy electron diffraction

Carbon storage in the organic layers of boreal forest soils under various moisture conditions: A model study for Northern Sweden sites

Sst II polymorphic sites in the promoter region of the human cystatin C gene